Uncovering the mode of action of engineered T cells in patient cancer organoids JF Dekkers, M Alieva, A Cleven, F Keramati, AKL Wezenaar, EJ van Vliet, ... Nature Biotechnology 41 (1), 60-69, 2023 | 119 | 2023 |
Patient-derived micro-organospheres enable clinical precision oncology S Ding, C Hsu, Z Wang, NR Natesh, R Millen, M Negrete, N Giroux, ... Cell Stem Cell 29 (6), 905-917. e6, 2022 | 110 | 2022 |
Tumor-infiltrating lymphocyte function predicts response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer JCH Kong, GR Guerra, RM Millen, S Roth, H Xu, PJ Neeson, PK Darcy, ... JCO Precision oncology 2, 1-15, 2018 | 76 | 2018 |
MAIT cells regulate NK cell-mediated tumor immunity EV Petley, HF Koay, MA Henderson, K Sek, KL Todd, SP Keam, J Lai, ... Nature communications 12 (1), 4746, 2021 | 69 | 2021 |
Patient-derived head and neck cancer organoids allow treatment stratification and serve as a tool for biomarker validation and identification R Millen, WWB De Kort, M Koomen, GJF van Son, R Gobits, BP de Vries, ... Med 4 (5), 290-310. e12, 2023 | 42 | 2023 |
Intestinal-specific activatable Myb initiates colon tumorigenesis in mice J Malaterre, L Pereira, T Putoczki, R Millen, S Paquet-Fifield, M Germann, ... Oncogene 35 (19), 2475-2484, 2016 | 27 | 2016 |
Rapid tissue prototyping with micro-organospheres Z Wang, M Boretto, R Millen, N Natesh, ES Reckzeh, C Hsu, M Negrete, ... Stem cell reports 17 (9), 1959-1975, 2022 | 21 | 2022 |
Immunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer R Millen, J Malaterre, RS Cross, S Carpinteri, J Desai, B Tran, P Darcy, ... Oncoimmunology 5 (7), e1149667, 2016 | 20 | 2016 |
CD8+ tumor‐infiltrating lymphocytes within the primary tumor of patients with synchronous de novo metastatic colorectal carcinoma do not track with survival R Millen, S Hendry, V Narasimhan, R Abbott, M Croxford, P Gibbs, J Tie, HL ... Clinical & Translational Immunology 9 (e115), 2020 | 19 | 2020 |
Toll-like Receptor Expression and Signaling in Peripheral Blood Mononuclear Cells Correlate With Clinical Outcomes in Acute Hepatitis C Virus Infection JS Swee Lin G. Chen Yi Mei, Jodie Burchell, Narelle Skinner, Rosie Millen ... The Journal of Infectious Diseases 214 (5), 739–747, 2016 | 19 | 2016 |
Impact of celecoxib on inflammation during cancer surgery: a randomized clinical trial Impact du célécoxib sur l’inflammation pendant les chirurgies du cancer: une étude … JG Hiller, S Sampurno, R Millen, BSN Kuruvilla, MKM Ho, R Ramsay, ... Can J Anesth/J Can Anesth 64, 497-505, 2017 | 17 | 2017 |
Experimental study of delivery of humidified-warm carbon dioxide during open abdominal surgery S Carpinteri, S Sampurno, J Malaterre, R Millen, M Dean, J Kong, ... Journal of British Surgery 105 (5), 597-605, 2018 | 16 | 2018 |
S201: Final 7-year follow up and retreatment substudy analysis of murano: venetoclax-rituximab (venr)-treated patients with relapsed/refractory chronic lymphocytic leukemia (R … A Kater, R Harrup, TJ Kipps, B Eichhorst, CJ Owen, S Assouline, ... HemaSphere 7, e492813f, 2023 | 15 | 2023 |
Medium-throughput drug-and radiotherapy screening assay using patient-derived organoids M Putker, R Millen, R Overmeer, E Driehuis, MMJM Zandvliet, H Clevers, ... JoVE (Journal of Visualized Experiments), e62495, 2021 | 15 | 2021 |
MURANO: Final 7 year follow up and retreatment analysis in venetoclax‐rituximab (VenR)‐treated patients with relapsed/refractory chronic lymphocytic leukemia (R/R CLL) AP Kater, R Harrup, TJ Kipps, B Eichhorst, CJ Owen, S Assouline, ... Hematological oncology 41 (S2), 239-242, 2023 | 11 | 2023 |
Levels of regulatory B cells do not predict serological responses to hepatitis B vaccine M Bolther, KLD Andersen, M Tolstrup, K Visvanathan, I Woolley, ... Human Vaccines & Immunotherapeutics 14 (6), 1483-1488, 2018 | 10 | 2018 |
Epidermal growth factor receptor (EGFR) is a target of the tumor-suppressor E3 ligase FBXW7 M Boretto, MH Geurts, S Gandhi, Z Ma, N Staliarova, M Celotti, S Lim, ... Proceedings of the National Academy of Sciences 121 (12), e2309902121, 2024 | 7 | 2024 |
Effect of surgical humidification on inflammation and peritoneal trauma in colorectal cancer surgery: a randomized controlled trial S Sampurno, T Chittleborough, M Dean, M Flood, S Carpinteri, S Roth, ... Annals of Surgical Oncology 29 (12), 7911-7920, 2022 | 7 | 2022 |
Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells P Hernández-López, E van Diest, P Brazda, S Heijhuurs, A Meringa, ... Nature Immunology 25 (1), 88-101, 2024 | 6 | 2024 |
Targeting of TP53-independent cell cycle checkpoints overcomes FOLFOX resistance in Metastatic Colorectal Cancer C Behrenbruch, M Foroutan, P Lind, J Smith, M Grandin, B Cooper, ... BioRxiv, 2021.02. 04.429849, 2021 | 6 | 2021 |