An immunogenic personal neoantigen vaccine for patients with melanoma PA Ott, Z Hu, DB Keskin, SA Shukla, J Sun, DJ Bozym, W Zhang, A Luoma, ... Nature 547 (7662), 217-221, 2017 | 2846 | 2017 |
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ... Cell 175 (4), 984-997. e24, 2018 | 1185 | 2018 |
A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing D Pan, A Kobayashi, P Jiang, L Ferrari de Andrade, RE Tay, AM Luoma, ... Science 359 (6377), 770-775, 2018 | 785 | 2018 |
MHC-II neoantigens shape tumour immunity and response to immunotherapy E Alspach, DM Lussier, AP Miceli, I Kizhvatov, M DuPage, AM Luoma, ... Nature 574 (7780), 696-701, 2019 | 765 | 2019 |
A molecular single-cell lung atlas of lethal COVID-19 JC Melms, J Biermann, H Huang, Y Wang, A Nair, S Tagore, I Katsyv, ... Nature 595 (7865), 114-119, 2021 | 598 | 2021 |
Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity L Ferrari de Andrade, RE Tay, D Pan, AM Luoma, Y Ito, S Badrinath, ... Science 359 (6383), 1537-1542, 2018 | 440 | 2018 |
Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma Z Hu, DE Leet, RL Allesøe, G Oliveira, S Li, AM Luoma, J Liu, J Forman, ... Nature medicine 27 (3), 515-525, 2021 | 412 | 2021 |
Molecular pathways of colon inflammation induced by cancer immunotherapy AM Luoma, S Suo, HL Williams, T Sharova, K Sullivan, M Manos, ... Cell 182 (3), 655-671. e22, 2020 | 389 | 2020 |
Distinct mesenchymal cell populations generate the essential intestinal BMP signaling gradient N McCarthy, E Manieri, EE Storm, A Saadatpour, AM Luoma, VN Kapoor, ... Cell stem cell 26 (3), 391-402. e5, 2020 | 306 | 2020 |
Neoadjuvant nivolumab or nivolumab plus ipilimumab in untreated oral cavity squamous cell carcinoma: a phase 2 open-label randomized clinical trial JD Schoenfeld, GJ Hanna, VY Jo, B Rawal, YH Chen, PS Catalano, ... JAMA oncology 6 (10), 1563-1570, 2020 | 283 | 2020 |
Crystal structure of Vδ1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human γδ T cells AM Luoma, CD Castro, T Mayassi, LA Bembinster, L Bai, D Picard, ... Immunity 39 (6), 1032-1042, 2013 | 264 | 2013 |
Human gamma delta T cells: evolution and ligand recognition EJ Adams, S Gu, AM Luoma Cellular immunology 296 (1), 31-40, 2015 | 245 | 2015 |
The adaptable major histocompatibility complex (MHC) fold: structure and function of nonclassical and MHC class I–like molecules EJ Adams, AM Luoma Annual review of immunology 31 (1), 529-561, 2013 | 233 | 2013 |
Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy AM Luoma, S Suo, Y Wang, L Gunasti, CBM Porter, N Nabilsi, J Tadros, ... Cell 185 (16), 2918-2935. e29, 2022 | 225 | 2022 |
Understanding and treating the inflammatory adverse events of cancer immunotherapy M Dougan, AM Luoma, SK Dougan, KW Wucherpfennig Cell 184 (6), 1575-1588, 2021 | 209 | 2021 |
The majority of CD1d‐sulfatide‐specific T cells in human blood use a semiinvariant Vδ1 TCR L Bai, D Picard, B Anderson, V Chaudhary, A Luoma, B Jabri, EJ Adams, ... European journal of immunology 42 (9), 2505-2510, 2012 | 208 | 2012 |
Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion CJ Frangieh, JC Melms, PI Thakore, KR Geiger-Schuller, P Ho, ... Nature genetics 53 (3), 332-341, 2021 | 197 | 2021 |
Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer S Shu, HJ Wu, YG Jennifer, R Zeid, IS Harris, B Jovanović, K Murphy, ... Molecular cell 78 (6), 1096-1113. e8, 2020 | 158 | 2020 |
Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments M Janiszewska, DP Tabassum, Z Castaño, S Cristea, KN Yamamoto, ... Nature cell biology 21 (7), 879-888, 2019 | 145 | 2019 |
SCAP is required for timely and proper myelin membrane synthesis MHG Verheijen, N Camargo, V Verdier, K Nadra, AS de Preux Charles, ... Proceedings of the National Academy of Sciences 106 (50), 21383-21388, 2009 | 135 | 2009 |