HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways F Guo, Q Zhao, M Sheraz, J Cheng, Y Qi, Q Su, A Cuconati, L Wei, Y Du, ... PLoS pathogens 13 (9), e1006658, 2017 | 132 | 2017 |
Activation of stimulator of interferon genes in hepatocytes suppresses the replication of hepatitis B virus F Guo, L Tang, S Shu, M Sehgal, M Sheraz, B Liu, Q Zhao, J Cheng, ... Antimicrobial agents and chemotherapy 61 (10), 10.1128/aac. 00771-17, 2017 | 78 | 2017 |
Hepatitis B virus core protein dephosphorylation occurs during pregenomic RNA encapsidation Q Zhao, Z Hu, J Cheng, S Wu, Y Luo, J Chang, J Hu, JT Guo Journal of virology 92 (13), 10.1128/jvi. 02139-17, 2018 | 71 | 2018 |
The current status and future directions of hepatitis B antiviral drug discovery L Tang, Q Zhao, S Wu, J Cheng, J Chang, JT Guo Expert opinion on drug discovery 12 (1), 5-15, 2017 | 71 | 2017 |
Preclinical profile of AB-423, an inhibitor of hepatitis B virus pregenomic RNA encapsidation N Mani, AG Cole, JR Phelps, A Ardzinski, KD Cobarrubias, A Cuconati, ... Antimicrobial agents and chemotherapy 62 (6), 10.1128/aac. 00082-18, 2018 | 62 | 2018 |
Discovery and mechanistic study of benzamide derivatives that modulate hepatitis B virus capsid assembly S Wu, Q Zhao, P Zhang, J Kulp, L Hu, N Hwang, J Zhang, TM Block, X Xu, ... Journal of virology 91 (16), 10.1128/jvi. 00519-17, 2017 | 53 | 2017 |
Interferon alpha induces multiple cellular proteins that coordinately suppress hepadnaviral covalently closed circular DNA transcription J Cheng, Q Zhao, Y Zhou, L Tang, M Sheraz, J Chang, JT Guo Journal of virology 94 (17), 10.1128/jvi. 00442-20, 2020 | 31 | 2020 |
Hepatitis B virus nucleocapsid uncoating: biological consequences and regulation by cellular nucleases J Hu, L Tang, J Cheng, T Zhou, Y Li, J Chang, Q Zhao, JT Guo Emerging microbes & infections 10 (1), 852-864, 2021 | 27 | 2021 |
Dual Roles of Two Isoforms of Autophagy-related Gene ATG10 in HCV-Subgenomic replicon Mediated Autophagy Flux and Innate Immunity Q Zhao, ZY Hu, JP Zhang, JD Jiang, Y Ma, J Li, Z Peng, J Chen Scientific reports 7 (1), 11250, 2017 | 27 | 2017 |
Characterization of novel hepadnaviral RNA species accumulated in hepatoma cells treated with viral DNA polymerase inhibitors P Zhang, F Liu, F Guo, Q Zhao, J Chang, JT Guo Antiviral research 131, 40-48, 2016 | 27 | 2016 |
Hedgehog signaling regulates osteoblast differentiation in zebrafish larvae through modulation of autophagy Z Hu, B Chen, Q Zhao Biology open 8 (5), bio040840, 2019 | 25 | 2019 |
Mechanism of interferon alpha therapy for chronic hepatitis B and potential approaches to improve its therapeutic efficacy Q Zhao, H Liu, L Tang, F Wang, G Tolufashe, J Chang, JT Guo Antiviral research 221, 105782, 2024 | 22 | 2024 |
Gene miles-apart is required for formation of otic vesicle and hair cells in zebrafish ZY Hu, QY Zhang, W Qin, JW Tong, Q Zhao, Y Han, J Meng, JP Zhang Cell death & disease 4 (10), e900-e900, 2013 | 17 | 2013 |
Have the Starting Lineup of Five for Hepatitis B Virus Covalently Closed Circular DNA Synthesis Been Identified? Q Zhao, JT Guo Hepatology 72 (3), 1142-1144, 2020 | 13 | 2020 |
The HBV capsid inhibitor AB-423 exhibits a dual mode of action and displays additive/synergistic effects in in vitro combination studies N Mani, AG Cole, A Ardzinski, D Cai, A Cuconati, BD Dorsey, F Guo, ... Hepatology 63 (1 SUPP), 123A-124A, 2016 | 13 | 2016 |
Pregenomic RNA Launch Hepatitis B virus replication system facilitates the mechanistic study of antiviral agents and drug-resistant variants on covalently closed circular DNA … Q Zhao, J Chang, R Rijnbrand, AM Lam, MJ Sofia, A Cuconati, JT Guo Journal of virology 96 (24), e01150-22, 2022 | 7 | 2022 |
补体旁路过度激活影响体内凝血功能 李敏, 孙黔云, 赵琼, 蒿雨露, 季仁升, 沈良贤 中国药理学通报 30 (1), 39-44, 2014 | 7 | 2014 |
香椿果抗补体活性多酚对补体损伤神经细胞的保护作用研究 赵琼, 孙黔云, 杨庆雄 中国药理学通报 27 (8), 1086-1090, 2011 | 6 | 2011 |
Heat shock protein family a member 1 promotes intracellular amplification of hepatitis B virus covalently closed circular DNA L Tang, P An, Q Zhao, CA Winkler, J Chang, JT Guo Journal of virology 97 (1), e01261-22, 2023 | 5 | 2023 |
4-Oxooctahydroquinoline-1 (2H)-carboxamides as hepatitis B virus (HBV) capsid core protein assembly modulators N Hwang, H Ban, S Wu, K McGuire, E Hernandez, J Chen, Q Zhao, ... Bioorganic & medicinal chemistry letters 58, 128518, 2022 | 5 | 2022 |