Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations AE Arrant, JR Roth, NR Boyle, SN Kashyap, MQ Hoffmann, CF Murchison, ... Acta neuropathologica communications 7, 1-17, 2019 | 64 | 2019 |
Alzheimer’s disease risk gene BIN1 induces Tau-dependent network hyperexcitability Y Voskobiynyk, JR Roth, JN Cochran, T Rush, NVN Carullo, JS Mesina, ... Elife 9, e57354, 2020 | 57 | 2020 |
A peptide inhibitor of Tau-SH3 interactions ameliorates amyloid-β toxicity T Rush, JR Roth, SJ Thompson, AR Aldaher, JN Cochran, ED Roberson Neurobiology of disease 134, 104668, 2020 | 32 | 2020 |
Delivering progranulin to neuronal lysosomes protects against excitotoxicity SE Davis, JR Roth, Q Aljabi, AR Hakim, KE Savell, JJ Day, AE Arrant Journal of Biological Chemistry 297 (3), 2021 | 19 | 2021 |
Circadian‐mediated regulation of cardiometabolic disorders and aging with time‐restricted feeding JR Roth, S Varshney, RCM de Moraes, GC Melkani Obesity 31, 40-49, 2023 | 16 | 2023 |
Rapamycin reduces neuronal mutant huntingtin aggregation and ameliorates locomotor performance in Drosophila JR Roth, RCM Moraes, BP Xu, SR Crawley, MA Khan, GC Melkani Frontiers in Aging Neuroscience 15, 1223911, 2023 | 10 | 2023 |
Development of small-molecule Tau-SH3 interaction inhibitors that prevent amyloid-β toxicity and network hyperexcitability JR Roth, T Rush, SJ Thompson, AR Aldaher, TB Dunn, JS Mesina, ... Neurotherapeutics 21 (1), e00291, 2024 | 6 | 2024 |
Race and the Ivory Tower: An Antiracism Exercise for an Undergraduate Neuroscience Classroom JR Roth, CF Gavin Journal of Undergraduate Neuroscience Education 20 (1), A40, 2021 | 3 | 2021 |
Apolipoprotein E Induces Lipid Accumulation Through Dgat2 That Is Prevented with Time-Restricted Feeding in Drosophila RCM Moraes, JR Roth, H Mao, SR Crawley, BP Xu, JC Watson, ... Genes 15 (11), 1376, 2024 | 2 | 2024 |
Development of small-molecule Tau-SH3 interaction inhibitors that prevent amyloid-β toxicity JR Roth, T Rush, DA Pugh, HB Dean, JN Cochran, SJ Thompson, ... 2021 Alzheimer's Association International Conference, 2021 | 1 | 2021 |
Progranulin acts in lysosomes to promote neuronal survival and growth AK Kaplelach, JA Hall, SE Davis, JR Roth, Q Aljabi, AR Hakim, K Savell, ... Alzheimer's Association International Conference, 2024 | | 2024 |
Tau-SH3 Interactions and Alzheimer's Disease J Roth The University of Alabama at Birmingham, 2021 | | 2021 |
Tau‐dependent regulation of neuronal activity by the Alzheimer’s disease risk gene BIN1 Molecular and cell biology/tau Y Voskobiynyk, JR Roth, JN Cochran, T Rush, NVN Carullo, M Waqas, ... Alzheimer's & Dementia 16, e045382, 2020 | | 2020 |
A peptide inhibitor of Tau-SH3 interactions ameliorates Aβ-induced dysfunction and network hyperexcitability JR Roth, T Rush, NVN Carullo, SJ Thompson, AR Aldaher, JS Mesina, ... AAIC Neuroscience Next, 2020 | | 2020 |
Tau-dependent regulation of neuronal activity by the Alzheimer’s disease risk gene BIN1 Y Voskobiynyk, JR Roth, JN Cochran, T Rush, NVN Carullo, M Waqas, ... 2020 Alzheimer's Association International Conference, 2020 | | 2020 |
P1‐186: IMPAIRED β‐GLUCOCEREBROSIDASE ACTIVITY AND PROCESSING IN FRONTOTEMPORAL DEMENTIA DUE TO PROGRANULIN MUTATIONS AE Arrant, NR Boyle, JR Roth, AN Li, S Spina, LT Grinberg, BL Miller, ... Alzheimer's & Dementia 15, P308-P308, 2019 | | 2019 |
P3‐106: THE ALZHEIMER'S DISEASE RISK GENE BIN1 REGULATES NETWORK HYPEREXCITABILITY Y Voskobiynyk, JN Cochran, T Rush, JR Roth, ED Roberson Alzheimer's & Dementia 14 (7S_Part_20), P1108-P1108, 2018 | | 2018 |