| Morphological and molecular defects in human three-dimensional retinal organoid model of X-linked juvenile retinoschisis KC Huang, ML Wang, SJ Chen, JC Kuo, WJ Wang, PNN Nguyen, ... Stem Cell Reports 13 (5), 906-923, 2019 | 90 | 2019 |
| Extension of retinofugal projections in an assembled model of human pluripotent stem cell-derived organoids CM Fligor, SS Lavekar, J Harkin, PK Shields, KB VanderWall, KC Huang, ... Stem Cell Reports 16 (9), 2228-2241, 2021 | 87 | 2021 |
| Retinal ganglion cells with a glaucoma OPTN (E50K) mutation exhibit neurodegenerative phenotypes when derived from three-dimensional retinal organoids KB VanderWall, KC Huang, Y Pan, SS Lavekar, CM Fligor, AR Allsop, ... Stem Cell Reports 15 (1), 52-66, 2020 | 74 | 2020 |
| Differentiation of retinal organoids from human pluripotent stem cells CM Fligor, KC Huang, SS Lavekar, KB VanderWall, JS Meyer Methods in Cell Biology 159, 279-302, 2020 | 56 | 2020 |
| Astrocytes modulate neurodegenerative phenotypes associated with glaucoma in OPTN (E50K) human stem cell-derived retinal ganglion cells C Gomes, KB VanderWall, Y Pan, X Lu, SS Lavekar, KC Huang, ... Stem Cell Reports 17 (7), 1636-1649, 2022 | 29 | 2022 |
| Development of a three-dimensional organoid model to explore early retinal phenotypes associated with Alzheimer’s disease SS Lavekar, J Harkin, M Hernandez, C Gomes, S Patil, KC Huang, ... Scientific Reports 13 (1), 13827, 2023 | 12 | 2023 |
| Enhanced mitochondrial biogenesis promotes neuroprotection in human pluripotent stem cell derived retinal ganglion cells M Surma, K Anbarasu, S Dutta, LJ Olivera Perez, KC Huang, JS Meyer, ... Communications Biology 6 (1), 218, 2023 | 12 | 2023 |
| A highly reproducible and efficient method for retinal organoid differentiation from human pluripotent stem cells J Harkin, KH Peña, C Gomes, M Hernandez, SS Lavekar, K So, K Lentsch, ... Proceedings of the National Academy of Sciences 121 (25), e2317285121, 2024 | 11 | 2024 |
| Generation of induced pluripotent stem cells from a patient with X-linked juvenile retinoschisis CH Peng, KC Huang, HE Lu, SH Syu, AA Yarmishyn, JF Lu, ... Stem Cell Research 29, 152-156, 2018 | 8 | 2018 |
| Induction of astrocyte reactivity promotes neurodegeneration in human pluripotent stem cell models C Gomes, KC Huang, J Harkin, A Baker, JM Hughes, Y Pan, K Tutrow, ... Stem Cell Reports 19 (8), 1122-1136, 2024 | 3 | 2024 |
| Autophagy disruption reduces mTORC1 activation leading to retinal ganglion cell neurodegeneration associated with glaucoma KC Huang, C Gomes, Y Shiga, N Belforte, KB VanderWall, SS Lavekar, ... bioRxiv, 2023 | 2 | 2023 |
| Micro-PET imaging of hepatitis C virus NS3/4A protease activity using a protease-activatable retention probe CH Chuang, TL Cheng, WC Chen, YJ Huang, HE Wang, YC Lo, YC Hsieh, ... Frontiers in Microbiology 13, 896588, 2022 | 2 | 2022 |
| Acquisition of neurodegenerative features in isogenic OPTN (E50K) human stem cell-derived retinal ganglion cells associated with autophagy disruption and mTORC1 signaling reduction KC Huang, C Gomes, Y Shiga, N Belforte, KB VanderWall, SS Lavekar, ... Acta Neuropathologica Communications 12 (1), 164, 2024 | 1 | 2024 |
| Towards the optimization of human stem cell-derived RGC integration in glaucomatous non-human primate retina J Leffler, M Hernandez, KC Huang, C Gomes, A Thanos, G Cull, M Dunn, ... Investigative Ophthalmology & Visual Science 64 (8), 4696-4696, 2023 | 1 | 2023 |
| Retinal ganglion cells in a dish: current strategies and recommended best practices for effective in vitro modeling of development and disease KC Huang, C Gomes, JS Meyer Human iPSC-derived Disease Models for Drug Discovery, 83-102, 2023 | 1 | 2023 |
| Retinal ganglion cell circuits and glial interactions in humans and mice KC Huang, M Tawfik, MA Samuel Trends in Neurosciences, 2024 | | 2024 |
| A human induced pluripotent stem cell model of Alzheimer’s Disease‐associated fractalkine receptor polymorphism to assess AD‐related microglial dysfunction K Tutrow, J Harkin, M Hernandez, KCS Huang, SJ Bissel, ... Alzheimer's & Dementia 20, e089429, 2024 | | 2024 |
| Exploring dysfunctional barrier phenotypes associated with glaucoma using a human pluripotent stem cell-based model of the neurovascular unit SS Lavekar, JM Hughes, C Gomes, KC Huang, J Harkin, SG Canfield, ... Fluids and Barriers of the CNS 21 (1), 90, 2024 | | 2024 |
| Reconstructing eye-to-brain contact and modulate synapse re-connection in hiPSC-retinal ganglion cells and brain targets KC Huang, A Ho, M Samuel Investigative Ophthalmology & Visual Science 65 (7), 6146-6146, 2024 | | 2024 |
| Induction of astrocyte reactivity promotes retinal ganglion cell degeneration in human pluripotent stem cell models through complement C3 activation C Gomes, KC Huang, J Harkin, AT Baker, J Hughes, Y Pan, S Lavekar, ... Investigative Ophthalmology & Visual Science 65 (7), 4513-4513, 2024 | | 2024 |