| The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway X Varelas, P Samavarchi-Tehrani, M Narimatsu, A Weiss, K Cockburn, ... Developmental cell 19 (6), 831-844, 2010 | 826 | 2010 |
| Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis F Liu, D Lagares, KM Choi, L Stopfer, A Marinković, V Vrbanac, CK Probst, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 308 (4 …, 2015 | 821 | 2015 |
| TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal X Varelas, R Sakuma, P Samavarchi-Tehrani, R Peerani, BM Rao, ... Nature cell biology 10 (7), 837-848, 2008 | 791 | 2008 |
| The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease X Varelas Development 141 (8), 1614-1626, 2014 | 752 | 2014 |
| The Hippo pathway regulates Wnt/β-catenin signaling X Varelas, BW Miller, R Sopko, S Song, A Gregorieff, FA Fellouse, ... Developmental cell 18 (4), 579-591, 2010 | 666 | 2010 |
| Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine A Dey, X Varelas, KL Guan Nature reviews Drug discovery 19 (7), 480-494, 2020 | 608 | 2020 |
| Switch enhancers interpret TGF-β and Hippo signaling to control cell fate in human embryonic stem cells TA Beyer, A Weiss, Y Khomchuk, K Huang, AA Ogunjimi, X Varelas, ... Cell reports 5 (6), 1611-1624, 2013 | 326 | 2013 |
| The transcriptional regulators TAZ and YAP direct transforming growth factor β-induced tumorigenic phenotypes in breast cancer cells*♦ SE Hiemer, AD Szymaniak, X Varelas Journal of Biological Chemistry 289 (19), 13461-13474, 2014 | 283 | 2014 |
| An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme DF Ceccarelli, X Tang, B Pelletier, S Orlicky, W Xie, V Plantevin, ... Cell 145 (7), 1075-1087, 2011 | 270 | 2011 |
| The hippo pathway effector Yap controls patterning and differentiation of airway epithelial progenitors JE Mahoney, M Mori, AD Szymaniak, X Varelas, WV Cardoso Developmental cell 30 (2), 137-150, 2014 | 256 | 2014 |
| Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis D Lagares, A Santos, PE Grasberger, F Liu, CK Probst, RA Rahimi, ... Science translational medicine 9 (420), eaal3765, 2017 | 218 | 2017 |
| Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis AJ Haak, E Kostallari, D Sicard, G Ligresti, KM Choi, N Caporarello, ... Science translational medicine 11 (516), eaau6296, 2019 | 191 | 2019 |
| Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors M Mori, JE Mahoney, MR Stupnikov, JR Paez-Cortez, AD Szymaniak, ... Development 142 (2), 258-267, 2015 | 172 | 2015 |
| Crumbs3-mediated polarity directs airway epithelial cell fate through the Hippo pathway effector Yap AD Szymaniak, JE Mahoney, WV Cardoso, X Varelas Developmental cell 34 (3), 283-296, 2015 | 163 | 2015 |
| Integrating developmental signals: a Hippo in the (path) way A Mauviel, F Nallet-Staub, X Varelas Oncogene 31 (14), 1743-1756, 2012 | 160 | 2012 |
| Systematic morphological profiling of human gene and allele function via Cell Painting MH Rohban, S Singh, X Wu, JB Berthet, MA Bray, Y Shrestha, X Varelas, ... Elife 6, e24060, 2017 | 151 | 2017 |
| A YAP/TAZ-regulated molecular signature is associated with oral squamous cell carcinoma SE Hiemer, L Zhang, VK Kartha, TS Packer, M Almershed, V Noonan, ... Molecular Cancer Research 13 (6), 957-968, 2015 | 131 | 2015 |
| The Hippo pathway effectors TAZ/YAP regulate dicer expression and microRNA biogenesis through Let-7 SG Chaulk, VJ Lattanzi, SE Hiemer, RP Fahlman, X Varelas Journal of Biological Chemistry 289 (4), 1886-1891, 2014 | 127 | 2014 |
| Stem cell regulation by the Hippo pathway SE Hiemer, X Varelas Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (2), 2323-2334, 2013 | 121 | 2013 |
| Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase discs overgrown R Sopko, E Silva, L Clayton, L Gardano, M Barrios-Rodiles, J Wrana, ... Current Biology 19 (13), 1112-1117, 2009 | 119 | 2009 |
