| Oral druggable space beyond the rule of 5: insights from drugs and clinical candidates BC Doak, B Over, F Giordanetto, J Kihlberg Chemistry & biology 21 (9), 1115-1142, 2014 | 784 | 2014 |
| Natural-product-derived fragments for fragment-based ligand discovery B Over, S Wetzel, C Grütter, Y Nakai, S Renner, D Rauh, H Waldmann Nature chemistry 5 (1), 21-28, 2013 | 341 | 2013 |
| Cell permeability beyond the rule of 5 P Matsson, BC Doak, B Over, J Kihlberg Advanced drug delivery reviews 101, 42-61, 2016 | 290 | 2016 |
| Impact of dynamically exposed polarity on permeability and solubility of chameleonic drugs beyond the rule of 5 M Rossi Sebastiano, BC Doak, M Backlund, V Poongavanam, B Over, ... Journal of medicinal chemistry 61 (9), 4189-4202, 2018 | 206 | 2018 |
| Structural and conformational determinants of macrocycle cell permeability B Over, P Matsson, C Tyrchan, P Artursson, BC Doak, MA Foley, ... Nature Chemical Biology 12 (12), 1065-1074, 2016 | 195 | 2016 |
| Impact of stereospecific intramolecular hydrogen bonding on cell permeability and physicochemical properties B Over, P McCarren, P Artursson, M Foley, F Giordanetto, G Grönberg, ... Journal of medicinal chemistry 57 (6), 2746-2754, 2014 | 92 | 2014 |
| Identification and further development of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis protein tyrosine … VV Vintonyak, K Warburg, B Over, K Hübel, D Rauh, H Waldmann Tetrahedron 67 (35), 6713-6729, 2011 | 70 | 2011 |
| Mining natural products for macrocycles to drug difficult targets F Begnini, V Poongavanam, B Over, M Castaldo, S Geschwindner, ... Journal of Medicinal Chemistry 64 (2), 1054-1072, 2020 | 41 | 2020 |
| Fragment‐Based Lead Discovery: Screening and Optimizing Fragments for Thermolysin Inhibition L Englert, K Silber, H Steuber, S Brass, B Over, HD Gerber, A Heine, ... ChemMedChem: Chemistry Enabling Drug Discovery 5 (6), 930-940, 2010 | 32 | 2010 |
| Formation of bicyclic cyclopentenone derivatives by Robinson-type annulation of cyclic β-oxoesters containing a 1, 4-diketone moiety I Geibel, C Kahrs, J Christoffers Synthesis 49 (17), 3874-3884, 2017 | 6 | 2017 |
| Erratum: Structural and conformational determinants of macrocycle cell permeability B Over, P Matsson, C Tyrchan, P Artursson, BC Doak, MA Foley, ... Nature chemical biology 13 (8), 922, 2017 | | 2017 |
| How to design cell permeable non-peptidic macrocycles B Over, P Matsson, C Tyrchan, P Artursson, B Doak, M Foley, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
| Macrocyclic drugs and clinical candidates-what are the limits of oral bioavailability? B Doak, B Over, F Giordanetto, J Kihlberg Abstracts of Papers of the American Chemical Society 248, 2014 | | 2014 |
| Chemoinformatische Entwicklung von Naturstofffragmenten, sowie deren strukturbiologische und biochemische Evaluierung zur fragmentbasierten Inhibitorentwicklung B Over Dortmund, Technische Universität, Diss., 2013, 2013 | | 2013 |
| Synthese von Thermolysininhibitoren unter Verwendung eines fragmentbasierten Ansatzes zur Wirkstoffentwicklung B Over | | 2008 |
| Extent of oral druggable space beyond the rule of 5: Learnings from drugs and clinical candidates BC Doak, B Over, F Giordanetto, J Kihlberg Chemistry & Biology, 0 | | |
Bradley DoakMonash UniversityEmail yang diverifikasi di monash.edu