| The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape DN Weinberg, S Papillon-Cavanagh, H Chen, Y Yue, X Chen, ... Nature 573 (7773), 281-286, 2019 | 486 | 2019 |
| Functional interrogation of DNA damage response variants with base editing screens R Cuella-Martin, SB Hayward, X Fan, X Chen, JW Huang, A Taglialatela, ... Cell 184 (4), 1081-1097. e19, 2021 | 205 | 2021 |
| The interplay between DNA and histone methylation: molecular mechanisms and disease implications Y Li, X Chen, C Lu EMBO reports 22 (5), e51803, 2021 | 163 | 2021 |
| N6-adenine DNA methylation is associated with the linker DNA of H2A.Z-containing well-positioned nucleosomes in Pol II-transcribed genes in Tetrahymena Y Wang, X Chen, Y Sheng, Y Liu, S Gao Nucleic Acids Research 45 (20), 11594–11606, 2017 | 117 | 2017 |
| Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands DN Weinberg, P Rosenbaum, X Chen, D Barrows, C Horth, MR Marunde, ... Nature Genetics 53 (6), 794-800, 2021 | 89 | 2021 |
| Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells C Liu, T Tate, E Batourina, ST Truschel, S Potter, M Adam, T Xiang, ... Nature Communications 10 (1), 4589, 2019 | 73 | 2019 |
| Genome analyses of the new model protist Euplotes vannus focusing on genome rearrangement and resistance to environmental stressors X Chen, Y Jiang, F Gao, W Zheng, TJ Krock, NA Stover, C Lu, LA Katz, ... Molecular Ecology Resources, 2019 | 69 | 2019 |
| Pparg signaling controls bladder cancer subtype and immune exclusion T Tate, T Xiang, SE Wobker, M Zhou, X Chen, H Kim, E Batourina, CS Lin, ... Nature Communications 12 (1), 6160, 2021 | 62 | 2021 |
| Chromatin dysregulation associated with NSD1 mutation in head and neck squamous cell carcinoma N Farhangdoost, C Horth, B Hu, E Bareke, X Chen, Y Li, M Coradin, ... Cell Reports 34 (8), 108769, 2021 | 59 | 2021 |
| A germline-limited piggyBac transposase gene is required for precise excision in Tetrahymena genome rearrangement L Feng, G Wang, EP Hamilton, J Xiong, G Yan, K Chen, X Chen, W Dui, ... Nucleic acids research 45 (16), 9481-9502, 2017 | 50 | 2017 |
| RNAi-dependent Polycomb repression controls transposable elements in Tetrahymena X Zhao, J Xiong, F Mao, Y Sheng, X Chen, L Feng, W Dui, W Yang, ... Genes & development 33 (5-6), 348-364, 2019 | 47 | 2019 |
| Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3. 3K36M oncohistone mutation KN Rajagopalan, X Chen, DN Weinberg, H Chen, J Majewski, CD Allis, ... Proceedings of the National Academy of Sciences 118 (9), e2021795118, 2021 | 44 | 2021 |
| Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas Y Li, EM Goldberg, X Chen, X Xu, JT McGuire, G Leuzzi, D Karagiannis, ... Molecular Cell 82 (20), 3901-3918. e7, 2022 | 38 | 2022 |
| Single substitution in H3. 3G34 alters DNMT3A recruitment to cause progressive neurodegeneration S Khazaei, CCL Chen, AF Andrade, N Kabir, P Azarafshar, SM Morcos, ... Cell 186 (6), 1162-1178. e20, 2023 | 37 | 2023 |
| Comparative genomics analysis of ciliates provides insights on the evolutionary history within" Nassophorea-Synhymenia-Phyllopharyngea" assemblage B Pan, X Chen, L Hou, Q Zhang, Z Qu, A Warren, M Miao Frontiers in Microbiology 10, 2819, 2019 | 36 | 2019 |
| GPSit: an automated method for evolutionary analysis of nonculturable ciliated microeukaryotes X Chen, Y Wang, Y Sheng, A Warren, S Gao Molecular Ecology Resources 18 (3), 700-713, 2018 | 36 | 2018 |
| A comparative study of genome organization and epigenetic mechanisms in model ciliates, with an emphasis on Tetrahymena, Paramecium and Oxytricha Y Wang, Y Wang, Y Sheng, J Huang, X Chen, KAS AL-Rasheid, S Gao European journal of protistology 61, 376-387, 2017 | 36 | 2017 |
| Phylogenomics of non-model ciliates based on transcriptomic analyses X Chen, X Zhao, X Liu, A Warren, F Zhao, M Miao Protein & cell 6 (5), 373-385, 2015 | 36 | 2015 |
| Enzymatic and chemical mapping of nucleosome distribution in purified micro- and macronuclei of the ciliated model organism, Tetrahymena thermophila X Chen, S Gao, Y Liu, Y Wang, Y Wang, W Song Science China Life Sciences 59, 909-919, 2016 | 34 | 2016 |
| Our recent progress in epigenetic research using the model ciliate, Tetrahymena thermophila T Cheng, Y Wang, J Huang, X Chen, X Zhao, S Gao, W Song Marine Life Science & Technology 1, 4-14, 2019 | 33 | 2019 |
Chao LuColumbia UniversityEmail yang diverifikasi di cumc.columbia.edu