| SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells L Li, T Osdal, Y Ho, S Chun, T McDonald, P Agarwal, A Lin, S Chu, J Qi, ... Cell stem cell 15 (4), 431-446, 2014 | 246 | 2014 |
| Mapping distinct bone marrow niche populations and their differentiation paths SL Wolock, I Krishnan, DE Tenen, V Matkins, V Camacho, S Patel, ... Cell reports 28 (2), 302-311. e5, 2019 | 225 | 2019 |
| Mesenchymal niche-specific expression of Cxcl12 controls quiescence of treatment-resistant leukemia stem cells P Agarwal, S Isringhausen, H Li, AJ Paterson, J He, Á Gomariz, ... Cell Stem Cell 24 (5), 769-784. e6, 2019 | 180 | 2019 |
| Osteoblast ablation reduces normal long-term hematopoietic stem cell self-renewal but accelerates leukemia development M Bowers, B Zhang, Y Ho, P Agarwal, CC Chen, R Bhatia Blood, The Journal of the American Society of Hematology 125 (17), 2678-2688, 2015 | 154 | 2015 |
| Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor–treated CML stem cells B Zhang, S Chu, P Agarwal, VL Campbell, L Hopcroft, HG Jørgensen, ... Blood, The Journal of the American Society of Hematology 128 (23), 2671-2682, 2016 | 125 | 2016 |
| Preferential killing of triple-negative breast cancer cells in vitro and in vivo when pharmacological aggravators of endoplasmic reticulum stress are combined with autophagy … S Thomas, N Sharma, EB Golden, H Cho, P Agarwal, KJ Gaffney, ... Cancer letters 325 (1), 63-71, 2012 | 88 | 2012 |
| SIRT1 regulates metabolism and leukemogenic potential in CML stem cells A Abraham, S Qiu, BK Chacko, H Li, A Paterson, J He, P Agarwal, M Shah, ... The Journal of clinical investigation 129 (7), 2685-2701, 2019 | 71 | 2019 |
| Enhanced targeting of CML stem and progenitor cells by inhibition of porcupine acyltransferase in combination with TKI A Puneet, B Zhang, H Yinwei, L Cook, Amy, Li, F Mikhail, Y Wang, ... Blood, 2016 | 69* | 2016 |
| Influence of Bone Marrow Microenvironment on Leukemic Stem Cells: Breaking Up an Intimate Relationship P Agarwal, R Bhatia Advances in Cancer Research, 2015 | 56 | 2015 |
| CXCR4 signaling has a CXCL12-independent essential role in murine MLL-AF9-driven acute myeloid leukemia R Ramakrishnan, P Peña-Martínez, P Agarwal, M Rodriguez-Zabala, ... Cell Reports 31 (8), 2020 | 44 | 2020 |
| TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling P Agarwal, H Li, K Choi, K Hueneman, J He, RS Welner, ... Cell reports 36 (2), 2021 | 24 | 2021 |
| TIFA and TIFAB: FHA-domain proteins involved in inflammation, hematopoiesis, and disease M Niederkorn, P Agarwal, DT Starczynowski Experimental Hematology 90, 18-29, 2020 | 24 | 2020 |
| Microenvironmental CXCL12 deletion enhances Flt3-ITD acute myeloid leukemia stem cell response to therapy by reducing p38 MAPK signaling NR Anderson, V Sheth, H Li, MW Harris, S Qiu, DK Crossman, H Kumar, ... Leukemia 37 (3), 560-570, 2023 | 17 | 2023 |
| Novel proteasome-inhibitory syrbactin analogs inducing endoplasmic reticulum stress and apoptosis in hematological tumor cell lines A Anshu, S Thomas, P Agarwal, TR Ibarra-Rivera, MC Pirrung, ... Biochemical pharmacology 82 (6), 600-609, 2011 | 16 | 2011 |
| Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML J Bennett, C Ishikawa, P Agarwal, J Yeung, A Sampson, E Uible, E Vick, ... Blood 142 (11), 989-1007, 2023 | 15 | 2023 |
| Mesenchymal niche-specific expression of Cxcl12 controls quiescence of treatment-resistant leukemia stem cells P Agarwal, S Isringhausen, H Li, AJ Paterson, J He, Á Gomariz, ... Cell Stem Cell 26 (1), 123, 2020 | 8 | 2020 |
| Role of CXCL12-expressing bone marrow populations in leukemic stem cell regulation P Agarwal, H Li, AJ Paterson, J He, T Nagasawa, R Bhatia Blood 128 (22), 26, 2016 | 8 | 2016 |
| Inactivation of p53 provides a competitive advantage to del (5q) myelodysplastic syndrome hematopoietic stem cells during inflammation T Muto, CS Walker, P Agarwal, E Vick, A Sampson, K Choi, M Niederkorn, ... Haematologica 108 (10), 2715, 2023 | 7 | 2023 |
| Role of enhanced autophagy in resistance of FLT3-ITD AML stem cells to FLT3 TKI treatment S Qiu, AJ Paterson, A Abraham, J He, M Shah, P Agarwal, AK Mullen, H Li, ... Blood 132, 1358, 2018 | 6 | 2018 |
| Inhibition of CML stem cell renewal by the porcupine inhibitor WNT974 P Agarwal, B Zhang, Y Ho, A Cook, L Li, Y Wang, ME Mclaughlin, ... Blood 126 (23), 54, 2015 | 5 | 2015 |