Ikuti
Nicholas K. Hurlburt
Nicholas K. Hurlburt
Staff Scientist
Email yang diverifikasi di fredhutch.org
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Tahun
Analysis of a SARS-CoV-2-infected individual reveals development of potent neutralizing antibodies with limited somatic mutation
E Seydoux, LJ Homad, AJ MacCamy, KR Parks, NK Hurlburt, ...
Immunity 53 (1), 98-105. e5, 2020
4042020
Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation
NK Hurlburt, E Seydoux, YH Wan, VV Edara, AB Stuart, J Feng, ...
Nature communications 11 (1), 5413, 2020
2022020
The receptor-like cytoplasmic kinase BIK1 localizes to the nucleus and regulates defense hormone expression during plant innate immunity
NK Lal, U Nagalakshmi, NK Hurlburt, R Flores, A Bak, P Sone, X Ma, ...
Cell host & microbe 23 (4), 485-497. e5, 2018
1392018
A potent anti-malarial human monoclonal antibody targets circumsporozoite protein minor repeats and neutralizes sporozoites in the liver
LT Wang, LS Pereira, Y Flores-Garcia, J O’Connor, BJ Flynn, A Schön, ...
Immunity 53 (4), 733-744. e8, 2020
1322020
Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects
MF Jennewein, AJ MacCamy, NR Akins, J Feng, LJ Homad, NK Hurlburt, ...
Cell reports 36 (2), 2021
1062021
Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit
NK Hurlburt, LJ Homad, I Sinha, MF Jennewein, AJ MacCamy, YH Wan, ...
Communications biology 5 (1), 342, 2022
612022
Characterization of neutralizing antibodies from a SARS-CoV-2 infected individual
E Seydoux, LJ Homad, AJ MacCamy, KR Parks, NK Hurlburt, ...
BioRxiv, 2020
612020
Structure of the Cladosporium fulvum Avr4 effector in complex with (GlcNAc)6 reveals the ligand-binding mechanism and uncouples its intrinsic function from …
NK Hurlburt, LH Chen, I Stergiopoulos, AJ Fisher
PLoS Pathogens 14 (8), e1007263, 2018
462018
Structural analysis of an Avr4 effector ortholog offers insight into chitin binding and recognition by the Cf-4 receptor
AC Kohler, LH Chen, N Hurlburt, A Salvucci, B Schwessinger, AJ Fisher, ...
The Plant Cell 28 (8), 1945-1965, 2016
412016
Highly protective antimalarial antibodies via precision library generation and yeast display screening
BB Banach, P Tripathi, L Da Silva Pereira, J Gorman, TD Nguyen, ...
Journal of Experimental Medicine 219 (8), e20220323, 2022
162022
Design of alphavirus virus-like particles presenting circumsporozoite junctional epitopes that elicit protection against malaria
JR Francica, W Shi, GY Chuang, SJ Chen, L Da Silva Pereira, SK Farney, ...
Vaccines 9 (3), 272, 2021
152021
The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria
LT Wang, NK Hurlburt, A Schön, BJ Flynn, Y Flores-Garcia, LS Pereira, ...
Cell reports 38 (7), 2022
132022
Broadly inhibitory antibodies against severe malaria virulence proteins
RA Reyes, SSR Raghavan, NK Hurlburt, V Introini, IH Kana, RW Jensen, ...
bioRxiv, 2024
42024
Structural characterization of a nonhydrolyzing UDP-GlcNAc 2-epimerase from Neisseria meningitidis serogroup A
NK Hurlburt, J Guan, H Ong, H Yu, X Chen, AJ Fisher
Acta Crystallographica Section F: Structural Biology Communications 76 (11 …, 2020
42020
Broadly inhibitory antibodies to severe malaria virulence proteins
RA Reyes, SSR Raghavan, NK Hurlburt, V Introini, S Bol, IH Kana, ...
Nature, 1-8, 2024
12024
Short CDRL1 in intermediate VRC01-like mAbs is not sufficient to overcome key glycan barriers on HIV-1 Env
P Agrawal, ML Knudsen, A MacCamy, NK Hurlburt, A Khechaduri, ...
Journal of Virology 98 (10), e00744-24, 2024
12024
Structural Determination and Analysis of Proteins Involved in the Plant Innate Immune System
NK Hurlburt
University of California, Davis, 2017
2017
Dna-conjugated antibodies for improved antibody affinity and reduced antibody cross reactivity
RW Davis, N Hurlburt, JM Zahn, M Javanmard, JA Mok
US Patent App. 14/899,472, 2016
2016
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