| ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways Y Zhang, Y Xiong, WG Yarbrough Cell 92 (6), 725-734, 1998 | 2178 | 1998 |
| Signaling to p53: ribosomal proteins find their way Y Zhang, H Lu Cancer cell 16 (5), 369-377, 2009 | 681 | 2009 |
| Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway Y Zhang, GW Wolf, K Bhat, A Jin, T Allio, WA Burkhart, Y Xiong Molecular and cellular biology 23 (23), 8902-8912, 2003 | 662 | 2003 |
| Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation K Itahana, KP Bhat, A Jin, Y Itahana, D Hawke, R Kobayashi, Y Zhang Molecular cell 12 (5), 1151-1164, 2003 | 548 | 2003 |
| A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation Y Zhang, Y Xiong Science 292 (5523), 1910-1915, 2001 | 521 | 2001 |
| Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53 Y Zhang, Y Xiong Molecular cell 3 (5), 579-591, 1999 | 494 | 1999 |
| Inhibition of HDM2 and activation of p53 by ribosomal protein L23 A Jin, K Itahana, K O'Keefe, Y Zhang Molecular and cellular biology 24 (17), 7669-7680, 2004 | 416 | 2004 |
| Ribosome biogenesis surveillance: probing the ribosomal protein-Mdm2-p53 pathway C Deisenroth, Y Zhang Oncogene 29 (30), 4253-4260, 2010 | 364 | 2010 |
| Essential role of ribosomal protein L11 in mediating growth inhibition‐induced p53 activation KP Bhat, K Itahana, A Jin, Y Zhang The EMBO journal 23 (12), 2402-2412, 2004 | 315 | 2004 |
| Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation K Itahana, H Mao, A Jin, Y Itahana, HV Clegg, MS Lindström, KP Bhat, ... Cancer cell 12 (4), 355-366, 2007 | 304 | 2007 |
| Optical induction of synaptic plasticity using a light-sensitive channel YP Zhang, TG Oertner Nature Methods 4 (2), 139-141, 2007 | 293 | 2007 |
| Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization S Stewart, M Sundaram, Y Zhang, J Lee, M Han, KL Guan Molecular and cellular biology 19 (8), 5523-5534, 1999 | 282 | 1999 |
| Control of p53 ubiquitination and nuclear export by MDM2 and ARF. Y Zhang, Y Xiong Cell growth & differentiation: the molecular biology journal of the American …, 2001 | 248 | 2001 |
| An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction E Macias, A Jin, C Deisenroth, K Bhat, H Mao, MS Lindström, Y Zhang Cancer cell 18 (3), 231-243, 2010 | 231 | 2010 |
| MDM2–p53 Pathway in Hepatocellular Carcinoma X Meng, DA Franklin, J Dong, Y Zhang Cancer research 74 (24), 7161-7167, 2014 | 229 | 2014 |
| Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11 M Sasaki, K Kawahara, M Nishio, K Mimori, R Kogo, K Hamada, B Itoh, ... Nature medicine 17 (8), 944-951, 2011 | 208 | 2011 |
| The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1 M Furukawa, Y Zhang, J McCarville, T Ohta, Y Xiong Molecular and cellular biology 20 (21), 8185-8197, 2000 | 183 | 2000 |
| Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination K O'Keefe, H Li, Y Zhang Molecular and cellular biology 23 (18), 6396-6405, 2003 | 180 | 2003 |
| Regulation of p53: a collaboration between Mdm2 and Mdmx D Pei, Y Zhang, J Zheng Oncotarget 3 (3), 228, 2012 | 179 | 2012 |
| Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation MS Lindström, A Jin, C Deisenroth, GW Wolf, Y Zhang Molecular and cellular biology 27 (3), 1056-1068, 2007 | 175 | 2007 |
