A network of chaperones prevents and detects failures in membrane protein lipid bilayer integration JPL Coelho, M Stahl, N Bloemeke, K Meighen-Berger, CP Alvira, ... Nature communications 10 (1), 672, 2019 | 45 | 2019 |
The human signal peptidase complex acts as a quality control enzyme for membrane proteins A Zanotti, JPL Coelho, D Kaylani, G Singh, M Tauber, M Hitzenberger, ... Science 378 (6623), 996-1000, 2022 | 23 | 2022 |
Quality control of mislocalized and orphan proteins KYE Kong, JPL Coelho, MJ Feige, A Khmelinskii Experimental Cell Research 403 (2), 112617, 2021 | 18 | 2021 |
Intramembrane client recognition potentiates the chaperone functions of calnexin N Bloemeke, K Meighen‐Berger, M Hitzenberger, NC Bach, M Parr, ... The EMBO Journal 41 (24), e110959, 2022 | 12 | 2022 |
The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center JPL Coelho, MCJ Yip, K Oltion, J Taunton, S Shao Nature Chemical Biology 20 (7), 877-884, 2024 | 8 | 2024 |
In case of stress, hold tight: phosphorylation switches PDI from an oxidoreductase to a holdase, tuning ER proteostasis JPL Coelho, MJ Feige The EMBO Journal 39 (10), e104880, 2020 | 3 | 2020 |
A molecular glue degrader of eRF1 on the ribosome S Shao, J Coelho Nature Chemical Biology, 2024 | 1 | 2024 |
A ‘NAC’for targeting proteins to the ER JPL Coelho, S Shao Trends in Biochemical Sciences 47 (9), 730-731, 2022 | 1 | 2022 |