| De novo design of a fluorescence-activating β-barrel J Dou, AA Vorobieva, W Sheffler, LA Doyle, H Park, MJ Bick, B Mao, ... Nature 561 (7724), 485-491, 2018 | 364 | 2018 |
| De novo design of transmembrane β barrels AA Vorobieva, P White, B Liang, JE Horne, AK Bera, CM Chow, S Gerben, ... Science 371 (6531), eabc8182, 2021 | 121 | 2021 |
| Incorporation of sensing modalities into de novo designed fluorescence-activating proteins JC Klima, LA Doyle, JD Lee, M Rappleye, LA Gagnon, MY Lee, EP Barros, ... Nature communications 12 (1), 856, 2021 | 47 | 2021 |
| Balancing specificity and promiscuity in enzyme evolution: multidimensional activity transitions in the alkaline phosphatase superfamily B Van Loo, CD Bayer, G Fischer, S Jonas, E Valkov, MF Mohamed, ... Journal of the American Chemical Society 141 (1), 370-387, 2018 | 44 | 2018 |
| Improving the efficiency of ligand-binding protein design with molecular dynamics simulations EP Barros, JM Schiffer, A Vorobieva, J Dou, D Baker, RE Amaro Journal of chemical theory and computation 15 (10), 5703-5715, 2019 | 31 | 2019 |
| Escherichia coli D-malate dehydrogenase, a generalist enzyme active in the leucine biosynthesis pathway AA Vorobieva, MS Khan, P Soumillion Journal of Biological Chemistry 289 (42), 29086-29096, 2014 | 23 | 2014 |
| Sculpting conducting nanopore size and shape through de novo protein design S Berhanu, S Majumder, T Müntener, J Whitehouse, C Berner, AK Bera, ... Science 385 (6706), 282-288, 2024 | 18 | 2024 |
| Design and optimization of enzymatic activity in a de novo β‐barrel scaffold Y Kipnis, AO Chaib, AA Vorobieva, G Cai, G Reggiano, B Basanta, ... Protein Science 31 (11), e4405, 2022 | 17 | 2022 |
| B-Cell Epitope Mapping of TprC and TprD Variants of Treponema pallidum Subspecies Informs Vaccine Development for Human Treponematoses B Molini, MC Fernandez, C Godornes, A Vorobieva, SA Lukehart, ... Frontiers in Immunology 13, 862491, 2022 | 17 | 2022 |
| Principles and methods in computational membrane protein design AA Vorobieva Journal of Molecular Biology 433 (20), 167154, 2021 | 15 | 2021 |
| Binding and sensing diverse small molecules using shape-complementary pseudocycles L An, M Said, L Tran, S Majumder, I Goreshnik, GR Lee, D Juergens, ... Science 385 (6706), 276-282, 2024 | 14* | 2024 |
| Treponema pallidum subsp. pallidum with an Artificially impaired TprK antigenic variation system is attenuated in the Rabbit model of syphilis E Romeis, NAP Lieberman, B Molini, LC Tantalo, B Chung, Q Phung, ... PLoS Pathogens 19 (3), e1011259, 2023 | 14 | 2023 |
| Evolutionary adaptation of the protein folding pathway for secretability D Smets, A Tsirigotaki, JH Smit, S Krishnamurthy, AG Portaliou, ... The EMBO Journal 41 (23), e111344, 2022 | 7 | 2022 |
| An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway D Chen, X Zhang, AA Vorobieva, R Tachibana, A Stein, RP Jakob, Z Zou, ... Nature chemistry 16 (10), 1656-1664, 2024 | 5 | 2024 |
| Validation of de novo designed water-soluble and transmembrane proteins by in silico folding and melting A Martin, C Berner, S Ovchinnikov, AA Vorobieva bioRxiv, 2023.06. 06.543955, 2023 | 5 | 2023 |
| Bacterial expression and protein purification of mini-fluorescence-activating proteins JC Klima, CM Chow, J Dou, AA Vorobieva, L Carter, D Baker | 5 | 2021 |
| Validation of de novo designed water‐soluble and transmembrane β‐barrels by in silico folding and melting AM Hermosilla, C Berner, S Ovchinnikov, AA Vorobieva Protein Science 33 (7), e5033, 2024 | 2 | 2024 |
| Evolutionary adaptation of the folding pathway for secretability D Smets, A Tsirigotaki, JH Smit, S Krishnamurthy, AG Portaliou, ... bioRxiv, 2022.04. 03.486881, 2022 | 2 | 2022 |
| How do you anticipate computational protein design will change biotechnology and therapeutic development? DN Woolfson, LJ Colwell, Z Chen, AA Vorobieva, NF Polizzi, A Stein, ... Cell Systems 15 (11), 994-999, 2024 | 1 | 2024 |
| Rationale in Custom Design of Transmembrane β-Barrel Pores AA Vorobieva Transmembrane β-Barrel Proteins: Methods and Protocols, 345-366, 2024 | 1 | 2024 |
