Ikuti
Robert Harkness
Robert Harkness
Email yang diverifikasi di utoronto.ca
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Dikutip oleh
Dikutip oleh
Tahun
Stabilization of i-motif structures by 2′-β-fluorination of DNA
HA Assi, RW Harkness, N Martin-Pintado, CJ Wilds, R Campos-Olivas, ...
Nucleic acids research 44 (11), 4998-5009, 2016
682016
G-quadruplex dynamics.
RW Harkness, AK Mittermaier
Biochimica et Biophysica acta. Proteins and Proteomics 1865 (11 Pt B), 1544-1554, 2017
622017
G-register exchange dynamics in guanine quadruplexes
RW Harkness, AK Mittermaier
Nucleic acids research 44 (8), 3481-3494, 2016
432016
Oligomeric assembly regulating mitochondrial HtrA2 function as examined by methyl-TROSY NMR
Y Toyama, RW Harkness, TYT Lee, JT Maynes, LE Kay
Proceedings of the National Academy of Sciences 118 (11), e2025022118, 2021
352021
Conformational dynamics of strand register shifts in DNA G-quadruplexes
JT Grün, C Hennecker, DP Klötzner, RW Harkness, I Bessi, A Heckel, ...
Journal of the American Chemical Society 142 (1), 264-273, 2019
342019
Mapping the energy landscapes of supramolecular assembly by thermal hysteresis
RW Harkness, N Avakyan, HF Sleiman, AK Mittermaier
Nature communications 9 (1), 3152, 2018
332018
Correlating histone acetylation with nucleosome core particle dynamics and function
TH Kim, ML Nosella, N Bolik-Coulon, RW Harkness, SK Huang, LE Kay
Proceedings of the National Academy of Sciences 120 (15), e2301063120, 2023
272023
Rapid characterization of folding and binding interactions with thermolabile ligands by DSC
RW Harkness, S Slavkovic, PE Johnson, AK Mittermaier
Chemical Communications 52 (92), 13471-13474, 2016
232016
Competing stress-dependent oligomerization pathways regulate self-assembly of the periplasmic protease-chaperone DegP
RW Harkness, Y Toyama, ZA Ripstein, H Zhao, AIM Sever, Q Luan, ...
Proceedings of the National Academy of Sciences 118 (32), e2109732118, 2021
192021
Poly (ADP-ribosyl) ation enhances nucleosome dynamics and organizes DNA damage repair components within biomolecular condensates
ML Nosella, TH Kim, SK Huang, RW Harkness, M Goncalves, A Pan, ...
Molecular Cell 84 (3), 429-446. e17, 2024
162024
Parallel reaction pathways accelerate folding of a guanine quadruplex
RW Harkness, C Hennecker, JT Grün, A Blümler, A Heckel, H Schwalbe, ...
Nucleic acids research 49 (3), 1247-1262, 2021
162021
Less is more: A simple methyl-TROSY based pulse scheme offers improved sensitivity in applications to high molecular weight complexes
N Bolik-Coulon, AIM Sever, RW Harkness, JM Aramini, Y Toyama, ...
Journal of Magnetic Resonance 346, 107326, 2023
152023
Structural basis of protein substrate processing by human mitochondrial high-temperature requirement A2 protease
Y Toyama, RW Harkness, LE Kay
Proceedings of the National Academy of Sciences 119 (17), e2203172119, 2022
152022
Dissecting the role of interprotomer cooperativity in the activation of oligomeric high-temperature requirement A2 protein
Y Toyama, RW Harkness, LE Kay
Proceedings of the National Academy of Sciences 118 (35), e2111257118, 2021
132021
Activation of caspase-9 on the apoptosome as studied by methyl-TROSY NMR
AIM Sever, TR Alderson, E Rennella, JM Aramini, ZH Liu, RW Harkness, ...
Proceedings of the National Academy of Sciences 120 (51), e2310944120, 2023
122023
Flexible client-dependent cages in the assembly landscape of the periplasmic protease-chaperone DegP
RW Harkness, ZA Ripstein, JM Di Trani, LE Kay
Journal of the American Chemical Society 145 (24), 13015-13026, 2023
82023
Global multi-method analysis of interaction parameters for reversibly self-associating macromolecules at high concentrations
A Parupudi, SK Chaturvedi, R Adão, RW Harkness, S Dragulin-Otto, ...
Scientific Reports 11 (1), 5741, 2021
72021
Analyzing multi-step ligand binding reactions for oligomeric proteins by NMR: Theoretical and computational considerations
RW Harkness, Y Toyama, LE Kay
Journal of Magnetic Resonance 318, 106802, 2020
72020
Experimental and computational determination of Brønsted coefficients for equilibrium transfer of the O,O‐dimethyl phosphorothioyl group between oxyanion …
DR Edwards, CI Maxwell, RW Harkness, AA Neverov, NJ Mosey, ...
Journal of Physical Organic Chemistry 25 (3), 258-266, 2012
52012
Exploring Host–Guest Interactions within a 600 kDa DegP Protease Cage Complex Using Hydrodynamics Measurements and Methyl-TROSY NMR
RW Harkness, H Zhao, Y Toyama, P Schuck, LE Kay
Journal of the American Chemical Society 146 (12), 8242-8259, 2024
22024
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