Antibody–Oligonucleotide Conjugates as Therapeutic, Imaging, and Detection Agents I Dovgan, O Koniev, S Kolodych, A Wagner Bioconjugate chemistry 30 (10), 2483-2501, 2019 | 144 | 2019 |
Discovery of Chemoselective and Biocompatible Reactions Using a High‐Throughput Immunoassay Screening S Kolodych, E Rasolofonjatovo, M Chaumontet, MC Nevers, C Créminon, ... Angewandte Chemie International Edition 52 (46), 12056-12060, 2013 | 140 | 2013 |
Targeting the tumour microenvironment with an enzyme-responsive drug delivery system for the efficient therapy of breast and pancreatic cancers B Renoux, F Raes, T Legigan, E Péraudeau, B Eddhif, P Poinot, ... Chemical Science 8 (5), 3427-3433, 2017 | 119 | 2017 |
Ultrafast Click Chemistry with Fluorosydnones H Liu, D Audisio, L Plougastel, E Decuypere, DA Buisson, O Koniev, ... Angewandte Chemie International Edition 55 (39), 12073-12077, 2016 | 119 | 2016 |
Iridium-Catalyzed Cycloaddition of Azides and 1-Bromoalkynes at Room Temperature E Rasolofonjatovo, S Theeramunkong, A Bouriaud, S Kolodych, ... Organic letters 15 (18), 4698-4701, 2013 | 116 | 2013 |
Bioorthogonal Click and Release Reaction of Iminosydnones with Cycloalkynes S Bernard, D Audisio, M Riomet, S Bregant, A Sallustrau, L Plougastel, ... Angewandte Chemie International Edition 56 (49), 15612-15616, 2017 | 114 | 2017 |
4-Halogeno-sydnones for fast strain promoted cycloaddition with bicyclo-[6.1. 0]-nonyne L Plougastel, O Koniev, S Specklin, E Decuypere, C Créminon, ... Chemical Communications 50 (66), 9376-9378, 2014 | 100 | 2014 |
CBTF: New amine-to-thiol coupling reagent for preparation of antibody conjugates with increased plasma stability S Kolodych, O Koniev, Z Baatarkhuu, JY Bonnefoy, F Debaene, ... Bioconjugate chemistry 26 (2), 197-200, 2015 | 86 | 2015 |
Development and evaluation of β-galactosidase-sensitive antibody-drug conjugates S Kolodych, C Michel, S Delacroix, O Koniev, A Ehkirch, J Eberova, ... European Journal of Medicinal Chemistry, 2017 | 72 | 2017 |
2-(Maleimidomethyl)-1, 3-Dioxanes (MD): a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation I Dovgan, S Kolodych, O Koniev, A Wagner Scientific Reports 6, 2016 | 64 | 2016 |
Palladium‐Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine‐Containing Molecules at Room Temperature RAA Al‐Shuaeeb, S Kolodych, O Koniev, S Delacroix, S Erb, S Nicolaÿ, ... Chemistry-A European Journal 22 (32), 11365-11370, 2016 | 60 | 2016 |
Copper (I)-Catalyzed Cycloaddition of 4-Bromosydnones and Alkynes for the Regioselective Synthesis of 1, 4, 5-Trisubstituted Pyrazoles E Decuypere, S Specklin, S Gabillet, D Audisio, H Liu, L Plougastel, ... Organic letters 17 (2), 362-365, 2015 | 56 | 2015 |
Acyl Fluorides: Fast, Efficient, and Versatile Lysine-Based Protein Conjugation via Plug-and-Play Strategy I Dovgan, S Ursuegui, S Erb, C Michel, S Kolodych, S Cianférani, ... Bioconjugate Chemistry 28 (5), 1452-1457, 2017 | 54 | 2017 |
Reaction Discovery by Using a Sandwich Immunoassay J Quinton, S Kolodych, M Chaumonet, V Bevilacqua, MC Nevers, ... Angewandte Chemie International Edition 51 (25), 6144-6148, 2012 | 47 | 2012 |
Design and Synthesis of Iminosydnones for Fast Click and Release Reactions with Cycloalkynes M Riomet, E Decuypere, K Porte, S Bernard, L Plougastel, S Kolodych, ... Chemistry–A European Journal 24 (34), 8535-8541, 2018 | 40 | 2018 |
Reduction–rebridging strategy for the preparation of ADPN-based antibody–drug conjugates O Koniev, I Dovgan, B Renoux, A Ehkirch, J Eberova, S Cianférani, ... MedChemComm 9 (5), 827-830, 2018 | 38 | 2018 |
On the use of DNA as a linker in antibody-drug conjugates: synthesis, stability and in vitro potency I Dovgan, A Ehkirch, V Lehot, I Kuhn, O Koniev, S Kolodych, A Hentz, ... Scientific Reports 10 (1), 1-9, 2020 | 28 | 2020 |
Automated linkage of proteins and payloads producing monodisperse conjugates I Dovgan, A Hentz, O Koniev, A Ehkirch, S Hessmann, S Ursuegui, ... Chemical Science 11 (5), 1210-1215, 2020 | 23 | 2020 |
MAPN: First-in-class reagent for kinetically resolved thiol-to-thiol conjugation O Koniev, S Kolodych, Z Baatarkhuu, J Stojko, J Eberova, JY Bonnefoy, ... Bioconjugate Chemistry 26 (9), 1863-1867, 2015 | 17 | 2015 |
Non-specific interactions of antibody-oligonucleotide conjugates with living cells V Lehot, I Kuhn, M Nothisen, S Erb, S Kolodych, S Cianférani, G Chaubet, ... Scientific Reports 11 (1), 5881, 2021 | 14 | 2021 |