Versatility of aminoglycosides and prospects for their future SB Vakulenko, S Mobashery Clinical microbiology reviews 16 (3), 430-450, 2003 | 941 | 2003 |
The basis for resistance to β-lactam antibiotics by penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus C Fuda, M Suvorov, SB Vakulenko, S Mobashery Journal of Biological Chemistry 279 (39), 40802-40806, 2004 | 387 | 2004 |
Multiplex PCR for detection of aminoglycoside resistance genes in enterococci SB Vakulenko, SM Donabedian, AM Voskresenskiy, MJ Zervos, ... Antimicrobial agents and chemotherapy 47 (4), 1423-1426, 2003 | 322 | 2003 |
Critical involvement of a carbamylated lysine in catalytic function of class D β-lactamases D Golemi, L Maveyraud, S Vakulenko, JP Samama, S Mobashery Proceedings of the National Academy of Sciences 98 (25), 14280-14285, 2001 | 306 | 2001 |
Design of novel antibiotics that bind to the ribosomal acyltransfer site J Haddad, LP Kotra, B Llano-Sotelo, C Kim, EF Azucena, M Liu, ... Journal of the American Chemical Society 124 (13), 3229-3237, 2002 | 207 | 2002 |
Class D β-lactamases: are they all carbapenemases? NT Antunes, TL Lamoureaux, M Toth, NK Stewart, H Frase, SB Vakulenko Antimicrobial agents and chemotherapy 58 (4), 2119-2125, 2014 | 181 | 2014 |
Insights into class D β-lactamases are revealed by the crystal structure of the OXA10 enzyme from Pseudomonas aeruginosa L Maveyraud, D Golemi, LP Kotra, S Tranier, S Vakulenko, S Mobashery, ... Structure 8 (12), 1289-1298, 2000 | 177 | 2000 |
Discovery of a new class of non-β-lactam inhibitors of penicillin-binding proteins with gram-positive antibacterial activity PI O’Daniel, Z Peng, H Pi, SA Testero, D Ding, E Spink, E Leemans, ... Journal of the American Chemical Society 136 (9), 3664-3672, 2014 | 159 | 2014 |
Characterization of fluoroquinolone-resistant mutant strains of Mycobacterium tuberculosis selected in the laboratory and isolated from patients GJ Alangaden, EK Manavathu, SB Vakulenko, NM Zvonok, SA Lerner Antimicrobial agents and chemotherapy 39 (8), 1700-1703, 1995 | 153 | 1995 |
Discovery of Antibiotic (E)-3-(3-Carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one R Bouley, M Kumarasiri, Z Peng, LH Otero, W Song, MA Suckow, ... Journal of the American Chemical Society 137 (5), 1738-1741, 2015 | 152 | 2015 |
Co-opting the Cell Wall in Fighting Methicillin-Resistant Staphylococcus aureus: Potent Inhibition of PBP 2a by Two Anti-MRSA β-Lactam Antibiotics A Villegas-Estrada, M Lee, D Hesek, SB Vakulenko, S Mobashery Journal of the American Chemical Society 130 (29), 9212-9213, 2008 | 142 | 2008 |
A synthetic dual drug sideromycin induces Gram-negative bacteria to commit suicide with a Gram-positive antibiotic R Liu, PA Miller, SB Vakulenko, NK Stewart, WC Boggess, MJ Miller Journal of medicinal chemistry 61 (9), 3845-3854, 2018 | 141 | 2018 |
Short alkylated peptoid mimics of antimicrobial lipopeptides NP Chongsiriwatana, TM Miller, M Wetzler, S Vakulenko, AJ Karlsson, ... Antimicrobial agents and chemotherapy 55 (1), 417-420, 2011 | 140 | 2011 |
Structural basis for carbapenemase activity of the OXA-23 β-lactamase from Acinetobacter baumannii CA Smith, NT Antunes, NK Stewart, M Toth, M Kumarasiri, M Chang, ... Chemistry & biology 20 (9), 1107-1115, 2013 | 129 | 2013 |
Resistance to β-Lactam Antibiotics and Its Mediation by the Sensor Domain of the Transmembrane BlaR Signaling Pathway in Staphylococcus aureus* 210 D Golemi-Kotra, JY Cha, SO Meroueh, SB Vakulenko, S Mobashery Journal of Biological Chemistry 278 (20), 18419-18425, 2003 | 108 | 2003 |
Structure–activity relationship for the oxadiazole class of antibiotics E Spink, D Ding, Z Peng, MA Boudreau, E Leemans, E Lastochkin, ... Journal of medicinal chemistry 58 (3), 1380-1389, 2015 | 102 | 2015 |
An antibiotic cloaked by its own resistance enzyme J Haddad, S Vakulenko, S Mobashery Journal of the American Chemical Society 121 (50), 11922-11923, 1999 | 100 | 1999 |
Structural Consequences of the Inhibitor-Resistant Ser130Gly Substitution in TEM β-Lactamase, VL Thomas, D Golemi-Kotra, C Kim, SB Vakulenko, S Mobashery, ... Biochemistry 44 (26), 9330-9338, 2005 | 97 | 2005 |
The importance of a critical protonation state and the fate of the catalytic steps in class A β-lactamases and penicillin-binding proteins D Golemi-Kotra, SO Meroueh, C Kim, SB Vakulenko, A Bulychev, ... Journal of Biological Chemistry 279 (33), 34665-34673, 2004 | 94 | 2004 |
Selection and characterization of β-lactam–β-lactamase inactivator-resistant mutants following PCR mutagenesis of the TEM-1 β-lactamase gene SB Vakulenko, B Geryk, LP Kotra, S Mobashery, SA Lerner Antimicrobial agents and chemotherapy 42 (7), 1542-1548, 1998 | 94 | 1998 |