CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities K Han, SE Pierce, A Li, K Spees, GR Anderson, JA Seoane, YH Lo, ... Nature 580 (7801), 136-141, 2020 | 270 | 2020 |
The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery M Toriyama, C Lee, SP Taylor, I Duran, DH Cohn, AL Bruel, JM Tabler, ... Nature genetics 48 (6), 648-656, 2016 | 162 | 2016 |
Drebrin restricts rotavirus entry by inhibiting dynamin-mediated endocytosis B Li, S Ding, N Feng, N Mooney, YS Ooi, L Ren, J Diep, MR Kelly, ... Proceedings of the National Academy of Sciences 114 (18), E3642-E3651, 2017 | 70 | 2017 |
Comparative proteomics reveals strain-specific β-TrCP degradation via rotavirus NSP1 hijacking a host Cullin-3-Rbx1 complex S Ding, N Mooney, B Li, MR Kelly, N Feng, AV Loktev, A Sen, JT Patton, ... PLoS pathogens 12 (10), e1005929, 2016 | 70 | 2016 |
A multi-scale map of cell structure fusing protein images and interactions Y Qin, EL Huttlin, CF Winsnes, ML Gosztyla, L Wacheul, MR Kelly, ... Nature 600 (7889), 536-542, 2021 | 69 | 2021 |
Interpretation of cancer mutations using a multiscale map of protein systems F Zheng, MR Kelly, DJ Ramms, ML Heintschel, K Tao, B Tutuncuoglu, ... Science 374 (6563), eabf3067, 2021 | 61 | 2021 |
Combined proteomic and genetic interaction mapping reveals new RAS effector pathways and susceptibilities MR Kelly, K Kostyrko, K Han, NA Mooney, EE Jeng, K Spees, PT Dinh, ... Cancer discovery 10 (12), 1950-1967, 2020 | 37 | 2020 |
Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth R Tang, EG Shuldiner, M Kelly, CW Murray, JD Hebert, L Andrejka, ... Nature cell biology 25 (1), 159-169, 2023 | 21 | 2023 |
A deep learning model of tumor cell architecture elucidates response and resistance to CDK4/6 inhibitors S Park, E Silva, A Singhal, MR Kelly, K Licon, I Panagiotou, C Fogg, ... Nature cancer 5 (7), 996-1009, 2024 | 20 | 2024 |
A multi-scale map of protein assemblies in the DNA damage response A Kratz, M Kim, MR Kelly, F Zheng, CA Koczor, J Li, K Ono, Y Qin, ... Cell systems 14 (6), 447-463. e8, 2023 | 20 | 2023 |
UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma K Kostyrko, M Román, AG Lee, DR Simpson, PT Dinh, SG Leung, ... Nature communications 14 (1), 3966, 2023 | 14 | 2023 |
University of Washington Center for Mendelian Genomics The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery M Toriyama, C Lee, SP Taylor, I Duran, DH Cohn, AL Bruel, JM Tabler, ... Nat. Genet 48, 648-656, 2016 | 8 | 2016 |
Duffourd Y, Faivre L, Rivière JB, Chen J, Liu KJ, Marcotte EM, Hildebrandt F, Thauvin-Robinet C, Krakow D, Jackson PK, Wallingford JB. The ciliopathy-associated CPLANE proteins … M Toriyama, C Lee, SP Taylor, I Duran, DH Cohn, AL Bruel, JM Tabler, ... Nat Genet 48, 648-56, 2016 | 7 | 2016 |
WRN inhibition leads to its chromatin-associated degradation via the PIAS4-RNF4-p97/VCP axis F Rodríguez Pérez, D Natwick, L Schiff, D McSwiggen, A Heckert, M Huey, ... Nature Communications 15 (1), 6059, 2024 | 2 | 2024 |
Multiplexed identification of RAS paralog imbalance as a driver of lung cancer growth R Tang, EG Shuldiner, M Kelly, CW Murray, JD Hebert, L Andrejka, ... bioRxiv, 2021.07. 08.451571, 2021 | 2 | 2021 |
Abstract B25: Combined proteomic and genetic interaction mapping reveals new Ras pathway effectors and regulators M Kelly, K Han, K Kostyrko, N Mooney, E Jeng, J Demeter, ... Molecular Cancer Research 18 (5_Supplement), B25-B25, 2020 | | 2020 |
Combinatorial knockout of Rap1GDS1 and RhoA leads to lethality in KRAS-driven non-small cell lung cancer. K Kostyrko, M Kelly, K Han, E Jeng, D Morgens, M Bassik, P Jackson, ... MOLECULAR CANCER RESEARCH 18 (5), 33-33, 2020 | | 2020 |
Abstract PR07: Combinatorial knockout of Rap1GDS1 and RhoA leads to lethality in KRAS-driven non-small cell lung cancer K Kostyrko, M Kelly, K Han, E Jeng, D Morgens, M Bassik, P Jackson, ... Molecular Cancer Research 18 (5_Supplement), PR07-PR07, 2020 | | 2020 |
Proteomic and Genomic Mapping of the RAS Pathway in Lung Adenocarcinoma MR Kelly Stanford University, 2020 | | 2020 |
A Physical and Genetic Interaction Map of the Ras Pathway in Lung Adenocarcinoma MR Kelly Stanford University, 2020 | | 2020 |