| Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease M Thambisetty, A Simmons, L Velayudhan, A Hye, J Campbell, Y Zhang, ... Archives of general psychiatry 67 (7), 739-748, 2010 | 503 | 2010 |
| Serum CA19-9 is significantly upregulated up to 2 years before diagnosis with pancreatic cancer: implications for early disease detection DP O'Brien, NS Sandanayake, C Jenkinson, A Gentry-Maharaj, ... Clinical Cancer Research 21 (3), 622-631, 2015 | 211 | 2015 |
| A blood atlas of COVID-19 defines hallmarks of disease severity and specificity DJ Ahern, Z Ai, M Ainsworth, C Allan, A Allcock, B Angus, MA Ansari, ... Cell 185 (5), 916-938. e58, 2022 | 210 | 2022 |
| Decreased serum thrombospondin-1 levels in pancreatic cancer patients up to 24 months prior to clinical diagnosis: association with diabetes mellitus C Jenkinson, VL Elliott, A Evans, L Oldfield, RE Jenkins, DP O'Brien, ... Clinical Cancer Research 22 (7), 1734-1743, 2016 | 95 | 2016 |
| Plasma gelsolin is decreased and correlates with rate of decline in Alzheimer's disease A Güntert, J Campbell, M Saleem, DP O'Brien, AJ Thompson, HL Byers, ... Journal of Alzheimer's Disease 21 (2), 585-596, 2010 | 91 | 2010 |
| MEMHDX: an interactive tool to expedite the statistical validation and visualization of large HDX-MS datasets V Hourdel, S Volant, DP O’Brien, A Chenal, J Chamot-Rooke, MA Dillies, ... Bioinformatics 32 (22), 3413-3419, 2016 | 73 | 2016 |
| Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion DP O’brien, B Hernandez, D Durand, V Hourdel, AC Sotomayor-Pérez, ... Scientific reports 5 (1), 14223, 2015 | 59 | 2015 |
| Structural disorder and induced folding within two cereal, ABA stress and ripening (ASR) proteins K Hamdi, E Salladini, DP O’Brien, S Brier, A Chenal, I Yacoubi, S Longhi Scientific reports 7 (1), 15544, 2017 | 56 | 2017 |
| Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis DP O’Brien, D Durand, A Voegele, V Hourdel, M Davi, J Chamot-Rooke, ... PLoS biology 15 (12), e2004486, 2017 | 40 | 2017 |
| Post‐translational acylation controls the folding and functions of the CyaA RTX toxin DP O'Brien, SE Cannella, A Voegele, D Raoux‐Barbot, M Davi, T Douche, ... The FASEB Journal 33 (9), 10065-10076, 2019 | 32 | 2019 |
| Identification of novel candidate biomarkers of epithelial ovarian cancer by profiling the secretomes of three‐dimensional genetic models of ovarian carcinogenesis K Lawrenson, P Mhawech‐Fauceglia, J Worthington, TJ Spindler, ... International journal of cancer 137 (8), 1806-1817, 2015 | 32 | 2015 |
| A High‐Affinity Calmodulin‐Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells A Voegele, M Sadi, DP O'Brien, P Gehan, D Raoux‐Barbot, M Davi, ... Advanced science 8 (9), 2003630, 2021 | 23 | 2021 |
| Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough DP O'Brien, ACS Perez, J Karst, SE Cannella, VYN Enguéné, A Hessel, ... Toxicon 149, 37-44, 2018 | 22 | 2018 |
| SEC‐SAXS and HDX‐MS: a powerful combination. The case of the calcium‐binding domain of a bacterial toxin DP O'Brien, S Brier, D Ladant, D Durand, A Chenal, P Vachette Biotechnology and applied biochemistry 65 (1), 62-68, 2018 | 22 | 2018 |
| Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19 CP Kotanidis, C Xie, D Alexander, JCL Rodrigues, K Burnham, A Mentzer, ... The Lancet Digital Health 4 (10), e705-e716, 2022 | 21 | 2022 |
| Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease SL Fowler, TS Behr, E Turkes, DP O’Brien, PM Cauhy, I Rawlinson, ... Nature Neuroscience, 1-9, 2024 | 19 | 2024 |
| Kidney and urinary tract GM Lum, JK Todd, D O’Brien Current Diagnosis & Treatment Paediatrics. 19th edition. New York: McGraw Hill, 2009 | 17 | 2009 |
| Employing TMT quantification in a shotgun-MS platform DP O’Brien, JF Timms Shotgun Proteomics: Methods and Protocols, 187-199, 2014 | 15 | 2014 |
| Structural premise of selective deubiquitinase USP30 inhibition by small-molecule benzosulfonamides DP O'Brien, HBL Jones, F Guenther, EJ Murphy, KS England, I Vendrell, ... Molecular & Cellular Proteomics 22 (8), 2023 | 14 | 2023 |
| Translocation and calmodulin-activation of the adenylate cyclase toxin (CyaA) of Bordetella pertussis A Voegele, DP O’Brien, O Subrini, N Sapay, SE Cannella, VYN Enguéné, ... Pathogens and disease 76 (8), fty085, 2018 | 14 | 2018 |