WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer L Castagnoli, V Cancila, SL Cordoba-Romero, S Faraci, G Talarico, ... Oncogene 38 (21), 4047-4060, 2019 | 187 | 2019 |
The biguanides metformin and phenformin inhibit angiogenesis, local and metastatic growth of breast cancer by targeting both neoplastic and microenvironment cells S Orecchioni, F Reggiani, G Talarico, P Mancuso, A Calleri, G Gregato, ... International journal of cancer 136 (6), E534-E544, 2015 | 154 | 2015 |
Vinorelbine, cyclophosphamide and 5-FU effects on the circulating and intratumoural landscape of immune cells improve anti-PD-L1 efficacy in preclinical models of breast cancer … S Orecchioni, G Talarico, V Labanca, A Calleri, P Mancuso, F Bertolini British journal of cancer 118 (10), 1329-1336, 2018 | 95 | 2018 |
Blastic plasmacytoid dendritic cell neoplasm: genomics mark epigenetic dysregulation as a primary therapeutic target MR Sapienza, F Abate, F Melle, S Orecchioni, F Fuligni, M Etebari, ... haematologica 104 (4), 729, 2018 | 80 | 2018 |
Adipose progenitor cell secretion of GM-CSF and MMP9 promotes a stromal and immunological microenvironment that supports breast cancer progression F Reggiani, V Labanca, P Mancuso, C Rabascio, G Talarico, S Orecchioni, ... Cancer research 77 (18), 5169-5182, 2017 | 79 | 2017 |
Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors D Sanchez-Martinez, N Allende-Vega, S Orecchioni, G Talarico, ... Theranostics 8 (14), 3856, 2018 | 64 | 2018 |
SPARC is a new myeloid-derived suppressor cell marker licensing suppressive activities S Sangaletti, G Talarico, C Chiodoni, B Cappetti, L Botti, P Portararo, ... Frontiers in immunology 10, 1369, 2019 | 63 | 2019 |
Aspirin and atenolol enhance metformin activity against breast cancer by targeting both neoplastic and microenvironment cells G Talarico, S Orecchioni, K Dallaglio, F Reggiani, P Mancuso, A Calleri, ... Scientific reports 6 (1), 18673, 2016 | 63 | 2016 |
Human leukemic cells performing oxidative phosphorylation (OXPHOS) generate an antioxidant response independently of reactive oxygen species (ROS) production AUH Khan, MG Rathore, N Allende-Vega, DN Vo, S Belkhala, ... EBioMedicine 3, 43-53, 2016 | 62 | 2016 |
Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells’ vulnerability to DNA-damaging agents A Cagnetta, D Soncini, S Orecchioni, G Talarico, P Minetto, F Guolo, ... haematologica 103 (1), 80, 2017 | 60 | 2017 |
Extracellular ATP induces apoptosis through P2X7R activation in acute myeloid leukemia cells but not in normal hematopoietic stem cells V Salvestrini, S Orecchioni, G Talarico, F Reggiani, C Mazzetti, F Bertolini, ... Oncotarget 8 (4), 5895, 2016 | 56 | 2016 |
The pan-class I phosphatidyl-inositol-3 kinase inhibitor NVP-BKM120 demonstrates anti-leukemic activity in acute myeloid leukemia M Allegretti, MR Ricciardi, R Licchetta, S Mirabilii, S Orecchioni, ... Scientific reports 5 (1), 18137, 2015 | 48 | 2015 |
The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism N Allende-Vega, E Krzywinska, S Orecchioni, N Lopez-Royuela, ... Oncotarget 6 (22), 19228, 2015 | 41 | 2015 |
Mitochondrial Complex I activity signals antioxidant response through ERK5 AUH Khan, N Allende-Vega, D Gitenay, J Garaude, DN Vo, S Belkhala, ... Scientific reports 8 (1), 7420, 2018 | 39 | 2018 |
The PDK1 inhibitor dichloroacetate controls cholesterol homeostasis through the ERK5/MEF2 pathway AUH Khan, N Allende-Vega, D Gitenay, S Gerbal-Chaloin, C Gondeau, ... Scientific reports 7 (1), 10654, 2017 | 29 | 2017 |
Mechanisms of obesity in the development of breast cancer S Orecchioni, F Reggiani, G Talarico, F Bertolini Discovery medicine 20 (109), 121-128, 2015 | 29 | 2015 |
Changes in metabolism affect expression of ABC transporters through ERK5 and depending on p53 status S Belkahla, AUH Khan, D Gitenay, C Alexia, C Gondeau, DN Vo, ... Oncotarget 9 (1), 1114, 2017 | 28 | 2017 |
SCD5-dependent inhibition of SPARC secretion hampers metastatic spreading and favors host immunity in a TNBC murine model M Bellenghi, G Talarico, L Botti, R Puglisi, C Tabolacci, P Portararo, ... Oncogene 41 (34), 4055-4065, 2022 | 19 | 2022 |
Impact of immune cell heterogeneity on HER2+ breast cancer prognosis and response to therapy M Perrone, G Talarico, C Chiodoni, S Sangaletti Cancers 13 (24), 6352, 2021 | 7 | 2021 |
BET inhibitors drive Natural Killer activation in non-small cell lung cancer via BRD4 and SMAD3 F Reggiani, G Talarico, G Gobbi, E Sauta, F Torricelli, V Manicardi, ... Nature Communications 15 (1), 2567, 2024 | 5 | 2024 |