Autophagy in Parkinson's disease X Hou, JO Watzlawik, FC Fiesel, W Springer Journal of molecular biology 432 (8), 2651-2672, 2020 | 314 | 2020 |
PINK1, Parkin, and mitochondrial quality control: what can we learn about Parkinson’s disease pathobiology? D Truban, X Hou, TR Caulfield, FC Fiesel, W Springer Journal of Parkinson’s disease 7 (1), 13-29, 2017 | 251 | 2017 |
Heterozygous PINK1 p. G411S increases risk of Parkinson’s disease via a dominant-negative mechanism A Puschmann, FC Fiesel, TR Caulfield, R Hudec, M Ando, D Truban, ... Brain 140 (1), 98-117, 2017 | 149 | 2017 |
Age-and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease X Hou, FC Fiesel, D Truban, M Castanedes Casey, W Lin, AI Soto, P Tacik, ... Autophagy 14 (8), 1404-1418, 2018 | 124 | 2018 |
Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease SO Adeosun, X Hou, Y Jiao, B Zheng, S Henry, R Hill, Z He, A Pani, ... PLoS One 7 (11), e50040, 2012 | 67 | 2012 |
Hexokinases link DJ-1 to the PINK1/parkin pathway DN Hauser, A Mamais, MM Conti, CT Primiani, R Kumaran, AA Dillman, ... Molecular neurodegeneration 12, 1-17, 2017 | 56 | 2017 |
Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology X Hou, JO Watzlawik, C Cook, CC Liu, SS Kang, WL Lin, M DeTure, ... Alzheimer's & Dementia 17 (3), 417-430, 2021 | 51 | 2021 |
Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples JO Watzlawik, X Hou, D Fricova, C Ramnarine, SK Barodia, TF Gendron, ... Autophagy 17 (9), 2613-2628, 2021 | 45 | 2021 |
Cognitive deficits and disruption of neurogenesis in a mouse model of apolipoprotein E4 domain interaction SO Adeosun, X Hou, B Zheng, C Stockmeier, X Ou, I Paul, T Mosley, ... Journal of Biological Chemistry 289 (5), 2946-2959, 2014 | 45 | 2014 |
A dominant negative ERβ splice variant determines the effectiveness of early or late estrogen therapy after ovariectomy in rats JM Wang, X Hou, S Adeosun, R Hill, S Henry, I Paul, RW Irwin, XM Ou, ... PloS one 7 (3), e33493, 2012 | 45 | 2012 |
Diverse immunostaining patterns of mineralocorticoid receptor monoclonal antibodies CE Gomez-Sanchez, M Warden, MT Gomez-Sanchez, X Hou, ... Steroids 76 (14), 1541-1545, 2011 | 30 | 2011 |
Differential contributions of ApoE4 and female sex to BACE1 activity and expression mediate Aβ deposition and learning and memory in mouse models of … X Hou, SO Adeosun, Q Zhang, B Barlow, M Brents, B Zheng, J Wang Frontiers in aging neuroscience 7, 207, 2015 | 23 | 2015 |
Alpha‐synuclein‐associated changes in PINK1‐PRKN‐mediated mitophagy are disease context dependent X Hou, THY Chen, S Koga, JM Bredenberg, AH Faroqi, M Delenclos, ... Brain Pathology 33 (5), e13175, 2023 | 20 | 2023 |
Substitution of PINK1 Gly411 modulates substrate receptivity and turnover FC Fiesel, D Fričová, CS Hayes, MA Coban, R Hudec, JM Bredenberg, ... Autophagy 19 (6), 1711-1732, 2023 | 19 | 2023 |
Human LRRK2 G2019S mutation represses post-synaptic protein PSD95 and causes cognitive impairment in transgenic mice SO Adeosun, X Hou, B Zheng, HL Melrose, T Mosley, JM Wang Neurobiology of learning and memory 142, 182-189, 2017 | 18 | 2017 |
Systematic Functional Analysis of PINK1 and PRKN Coding Variants BJ Broadway, PK Boneski, JM Bredenberg, A Kolicheski, X Hou, ... Cells 11 (15), 2426, 2022 | 16 | 2022 |
Cathepsin B p. Gly284Val variant in Parkinson’s disease pathogenesis LM Milanowski, X Hou, JM Bredenberg, FC Fiesel, LT Cocker, ... International journal of molecular sciences 23 (13), 7086, 2022 | 15 | 2022 |
Basal activity of PINK1 and PRKN in cell models and rodent brain JO Watzlawik, FC Fiesel, G Fiorino, BA Bustillos, Z Baninameh, ... Autophagy 20 (5), 1147-1158, 2024 | 11 | 2024 |
Role of GBA variants in Lewy body disease neuropathology RL Walton, S Koga, AI Beasley, LJ White, T Griesacker, ME Murray, ... Acta neuropathologica 147 (1), 54, 2024 | 8 | 2024 |
Female mice with apolipoprotein E4 domain interaction demonstrated impairments in spatial learning and memory performance and disruption of hippocampal cyto-architecture SO Adeosun, X Hou, L Shi, CA Stockmeier, B Zheng, RL Raffai, ... Neurobiology of learning and memory 161, 106-114, 2019 | 6 | 2019 |