| Rapid blue-light–mediated induction of protein interactions in living cells MJ Kennedy, RM Hughes, LA Peteya, JW Schwartz, MD Ehlers, ... Nature methods 7 (12), 973-975, 2010 | 1280 | 2010 |
| Optimized second-generation CRY2–CIB dimerizers and photoactivatable Cre recombinase A Taslimi, B Zoltowski, JG Miranda, GP Pathak, RM Hughes, CL Tucker Nature chemical biology 12 (6), 425-430, 2016 | 289 | 2016 |
| Model systems for β-hairpins and β-sheets RM Hughes, ML Waters Current opinion in structural biology 16 (4), 514-524, 2006 | 227 | 2006 |
| Recognition of trimethyllysine by a chromodomain is not driven by the hydrophobic effect RM Hughes, KR Wiggins, S Khorasanizadeh, ML Waters Proceedings of the National Academy of Sciences 104 (27), 11184-11188, 2007 | 201 | 2007 |
| Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival PA Gagliardi, M Dobrzyński, MA Jacques, C Dessauges, P Ender, Y Blum, ... Developmental cell 56 (12), 1712-1726. e6, 2021 | 125 | 2021 |
| Influence of N-Methylation on a Cation−π Interaction Produces a Remarkably Stable β-Hairpin Peptide RM Hughes, ML Waters Journal of the American Chemical Society 127 (18), 6518-6519, 2005 | 116 | 2005 |
| Light-mediated control of DNA transcription in yeast RM Hughes, S Bolger, H Tapadia, CL Tucker Methods 58 (4), 385-391, 2012 | 111 | 2012 |
| Arginine Methylation in a β-Hairpin Peptide: Implications for Arg−π Interactions, ΔCp°, and the Cold Denatured State RM Hughes, ML Waters Journal of the American Chemical Society 128 (39), 12735-12742, 2006 | 105 | 2006 |
| Effects of Lysine Acetylation in a β-Hairpin Peptide: Comparison of an Amide− π and a Cation− π Interaction RM Hughes, ML Waters Journal of the American Chemical Society 128 (41), 13586-13591, 2006 | 83 | 2006 |
| Effects of Chain Length and N‐Methylation on a Cation–π Interaction in a β‐Hairpin Peptide RM Hughes, ML Benshoff, ML Waters Chemistry–A European Journal 13 (20), 5753-5764, 2007 | 79 | 2007 |
| Optogenetic apoptosis: light‐triggered cell death RM Hughes, DJ Freeman, KN Lamb, RM Pollet, WJ Smith, DS Lawrence Angewandte Chemie 127 (41), 12232-12236, 2015 | 69 | 2015 |
| Orientation and alkylation effects on cation-π interactions in aqueous solution MJ Rashkin, RM Hughes, NT Calloway, ML Waters Journal of the American Chemical Society 126 (41), 13320-13325, 2004 | 62 | 2004 |
| B12-Mediated, Long Wavelength Photopolymerization of Hydrogels ZL Rodgers, RM Hughes, LM Doherty, JR Shell, BP Molesky, AM Brugh, ... Journal of the American Chemical Society 137 (9), 3372-3378, 2015 | 57 | 2015 |
| Cell‐mediated assembly of phototherapeutics WJ Smith, NP Oien, RM Hughes, CM Marvin, ZL Rodgers, J Lee, ... Angewandte Chemie 126 (41), 11125-11128, 2014 | 57 | 2014 |
| Transthyretin aggregation pathway toward the formation of distinct cytotoxic oligomers AKR Dasari, RM Hughes, S Wi, I Hung, Z Gan, JW Kelly, KH Lim Scientific reports 9 (1), 33, 2019 | 54 | 2019 |
| Light-dependent, Dark-promoted Interaction between Arabidopsis Cryptochrome 1 and Phytochrome B Proteins*♦ RM Hughes, JD Vrana, J Song, CL Tucker Journal of Biological Chemistry 287 (26), 22165-22172, 2012 | 46 | 2012 |
| Design and profiling of a subcellular targeted optogenetic cAMP-dependent protein kinase CP O'Banion, MA Priestman, RM Hughes, LE Herring, SJ Capuzzi, ... Cell Chemical Biology 25 (1), 100-109. e8, 2018 | 36 | 2018 |
| Optogenetic Engineering: Light‐Directed Cell Motility RM Hughes, DS Lawrence Angewandte Chemie 126 (41), 11084-11087, 2014 | 33 | 2014 |
| Phototriggered secretion of membrane compartmentalized bioactive agents RM Hughes, CM Marvin, ZL Rodgers, S Ding, NP Oien, WJ Smith, ... Angewandte Chemie International Edition 55 (52), 16080-16083, 2016 | 31 | 2016 |
| A compendium of chemical and genetic approaches to light-regulated gene transcription RM Hughes Critical reviews in biochemistry and molecular biology 53 (5), 453-474, 2018 | 27 | 2018 |
