Margarida Amaral

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Carlos Miguel FarinhaAssociate Professor of BiochemistryEmail yang diverifikasi di fc.ul.pt
Luka A. ClarkeBIOISI: Biosystems & Integrative Sciences Institute, University of Lisbon, PortugalEmail yang diverifikasi di fc.ul.pt
Hugo M. BotelhoBioISI - Faculdade de Ciências, Universidade de LisboaEmail yang diverifikasi di ciencias.ulisboa.pt
Nikhil T AwatadeUniversity of NewcastleEmail yang diverifikasi di newcastle.edu.au
Rainer PepperkokTeamleader, EMBL, Heidelberg GermanyEmail yang diverifikasi di embl.de
Dr Daniel GrahamFaculty of Science Senior Research Officer, LJMUEmail yang diverifikasi di ljmu.ac.uk
Hugo Alexandre FerreiraIBEB, Faculdade de Ciências da Universidade de Lisboa, PortugalEmail yang diverifikasi di fc.ul.pt
Scott BellEmail yang diverifikasi di health.qld.gov.au
Philip J ThomasProfessor UT SouthwesternEmail yang diverifikasi di utsouthwestern.edu
Rachel KarchinProfessor of Biomedical Engineering, Oncology and Computer Science, Johns Hopkins UniversityEmail yang diverifikasi di jhu.edu
Neeraj SharmaAssistant Professor, Department of Genetic Medicine, Director Primary Cell CoreEmail yang diverifikasi di jh.edu
Maria de Fatima Corrêa Pimenta Servi...Medica gastropediatra Gastrocentro e FCM-UNICAMPEmail yang diverifikasi di gc.unicamp.br
Gergely L. LukacsMcGill UniversityEmail yang diverifikasi di mcgill.ca
Richard I. MorimotoBill and Gayle Cook Professor of Biology, Dept of Molecular Biosciences, NorthwesternEmail yang diverifikasi di northwestern.edu
Michael A GrayNewcastle UniversityEmail yang diverifikasi di newcastle.ac.uk
Jose Dirceu RibeiroSate University of Campinas - UNICAMP - BrazilEmail yang diverifikasi di unicamp.br
Rui MalhóEmail yang diverifikasi di fc.ul.pt
Luis P FonsecaAssociate Professor, Bioengineering Departament, Instituto Superior TécnicoEmail yang diverifikasi di tecnico.ulisboa.pt
Joaquim M S CabralDistinguished Professor of Bioengineering, Instituto Superior Técnico, University of LisbonEmail yang diverifikasi di tecnico.ulisboa.pt
Cláudio M. GomesFaculty of Sciences University of Lisbon, BioISI and Department of Chemistry and BiochemistryEmail yang diverifikasi di fc.ul.pt

Ikuti

Margarida Amaral

Professor of Molecular Biology, Faculty of Sciences, University of Lisboa

Email yang diverifikasi di fc.ul.pt - Beranda

Molecular & Cell Biology Membrane Proteins Cystic Fibrosis


Judul Urutkan menurut kutipan Urutkan menurut tahun Urutkan menurut judul	Dikutip oleh Dikutip oleh	Tahun
Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene PR Sosnay, KR Siklosi, F Van Goor, K Kaniecki, H Yu, N Sharma, ... Nature genetics 45 (10), 1160-1167, 2013	724	2013
Progress in therapies for cystic fibrosis K De Boeck, MD Amaral The Lancet Respiratory Medicine 4 (8), 662-674, 2016	548	2016
Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei D Zink, MD Amaral, A Englmann, S Lang, LA Clarke, C Rudolph, F Alt, ... Journal of Cell Biology 166 (6), 815-825, 2004	323	2004
CFTR modulator theratyping: Current status, gaps and future directions JP Clancy, CU Cotton, SH Donaldson, GM Solomon, DR VanDevanter, ... Journal of Cystic Fibrosis 18 (1), 22-34, 2019	288	2019
New pharmacological approaches for cystic fibrosis: promises, progress, pitfalls SC Bell, K De Boeck, MD Amaral Pharmacology & therapeutics 145, 19-34, 2015	258	2015
Most F508del-CFTR is targeted to degradation at an early folding checkpoint and independently of calnexin CM Farinha, MD Amaral Molecular and cellular biology 25 (12), 5242-5252, 2005	258	2005
CFTR and chaperones: processing and degradation MD Amaral Journal of Molecular Neuroscience 23, 41-48, 2004	220	2004
Five percent of normal cystic fibrosis transmembrane conductance regulator mRNA ameliorates the severity of pulmonary disease in cystic fibrosis AS Ramalho, S Beck, M Meyer, D Penque, GR Cutting, MD Amaral American journal of respiratory cell and molecular biology 27 (5), 619-627, 2002	216	2002
Revertants, low temperature, and correctors reveal the mechanism of F508del-CFTR rescue by VX-809 and suggest multiple agents for full correction CM Farinha, J King-Underwood, M Sousa, AR Correia, BJ Henriques, ... Chemistry & biology 20 (7), 943-955, 2013	196	2013
Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis MD Amaral, K Kunzelmann Trends in pharmacological sciences 28 (7), 334-341, 2007	188	2007
Novel personalized therapies for cystic fibrosis: treating the basic defect in all patients MD Amaral Journal of internal medicine 277 (2), 155-166, 2015	173	2015
The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator … CM Farinha, P Nogueira, F Mendes, D Penque, MD Amaral Biochemical Journal 366 (3), 797-806, 2002	168	2002
CFTR Cl− channel function in native human colon correlates with the genotype and phenotype in cystic fibrosis S Hirtz, T Gonska, HH Seydewitz, J Thomas, P Greiner, J Kuehr, ... Gastroenterology 127 (4), 1085-1095, 2004	161	2004
Processing of CFTR: traversing the cellular maze—how much CFTR needs to go through to avoid cystic fibrosis? MD Amaral Pediatric pulmonology 39 (6), 479-491, 2005	158	2005
Epithelial chloride transport by CFTR requires TMEM16A R Benedetto, J Ousingsawat, P Wanitchakool, Y Zhang, MJ Holtzman, ... Scientific reports 7 (1), 12397, 2017	143	2017
A genetic screening strategy identifies novel regulators of the proteostasis network MC Silva, S Fox, M Beam, H Thakkar, MD Amaral, RI Morimoto PLoS genetics 7 (12), e1002438, 2011	139	2011
Revertant mutants G550E and 4RK rescue cystic fibrosis mutants in the first nucleotide-binding domain of CFTR by different mechanisms M Roxo-Rosa, Z Xu, A Schmidt, M Neto, Z Cai, CM Soares, DN Sheppard, ... Proceedings of the National Academy of Sciences 103 (47), 17891-17896, 2006	139	2006
Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells SM Garcia, MO Casanueva, MC Silva, MD Amaral, RI Morimoto Genes & development 21 (22), 3006-3016, 2007	133	2007
Magnetic field-assisted DNA hybridisation and simultaneous detection using micron-sized spin-valve sensors and magnetic nanoparticles DL Graham, HA Ferreira, N Feliciano, PP Freitas, LA Clarke, MD Amaral Sensors and Actuators B: Chemical 107 (2), 936-944, 2005	131	2005
Cystic fibrosis F508del patients have apically localized CFTR in a reduced number of airway cells D Penque, F Mendes, S Beck, C Farinha, P Pacheco, P Nogueira, ... Laboratory investigation 80 (6), 857-868, 2000	125	2000

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