Alzheimer disease: an update on pathobiology and treatment strategies JM Long, DM Holtzman Cell 179 (2), 312-339, 2019 | 2615 | 2019 |
Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model Y Shi, M Manis, J Long, K Wang, PM Sullivan, J Remolina Serrano, ... Journal of Experimental Medicine 216 (11), 2546-2561, 2019 | 364 | 2019 |
MicroRNA-101 downregulates Alzheimer’s amyloid-β precursor protein levels in human cell cultures and is differentially expressed JM Long, DK Lahiri Biochemical and biophysical research communications 404 (4), 889-895, 2011 | 262 | 2011 |
MicroRNA-153 physiologically inhibits expression of amyloid-β precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients JM Long, B Ray, DK Lahiri Journal of Biological Chemistry 287 (37), 31298-31310, 2012 | 232 | 2012 |
MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue … JM Long, B Ray, DK Lahiri Journal of Biological Chemistry 289 (8), 5184-5198, 2014 | 209 | 2014 |
Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links DK Sokol, B Maloney, JM Long, B Ray, DK Lahiri Neurology 76 (15), 1344-1352, 2011 | 176 | 2011 |
Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5′-untranslated region: Implications in Alzheimer’s disease JM Long, B Maloney, JT Rogers, DK Lahiri Molecular psychiatry 24 (3), 345-363, 2019 | 147 | 2019 |
Increased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarker B Ray, JM Long, DK Sokol, DK Lahiri PLoS One 6 (6), e20405, 2011 | 134 | 2011 |
Lessons from a BACE1 inhibitor trial: off‐site but not off base DK Lahiri, B Maloney, JM Long, NH Greig Alzheimer's & Dementia 10, S411-S419, 2014 | 108 | 2014 |
Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research B Ray, N Chopra, JM Long, DK Lahiri Molecular brain 7 (1), 63, 2014 | 58 | 2014 |
Select Atrophied Regions in Alzheimer disease (SARA): An improved volumetric model for identifying Alzheimer disease dementia LN Koenig, GS Day, A Salter, S Keefe, LM Marple, J Long, P LaMontagne, ... NeuroImage: Clinical, 102248, 2020 | 53 | 2020 |
Advances in microRNA experimental approaches to study physiological regulation of gene products implicated in CNS disorders JM Long, DK Lahiri Experimental neurology 235 (2), 402-418, 2012 | 47 | 2012 |
Regulation of astrocyte lipid metabolism and ApoE secretion by the microglial oxysterol, 25-hydroxycholesterol AG Cashikar, D Toral-Rios, D Timm, J Romero, M Strickland, JM Long, ... Journal of lipid research 64 (4), 2023 | 37 | 2023 |
Current drug targets for modulating Alzheimer's amyloid precursor protein: role of specific micro-RNA species JM Long, DK Lahiri Current medicinal chemistry 18 (22), 3314-3321, 2011 | 36 | 2011 |
Preclinical Alzheimer’s disease biomarkers accurately predict cognitive and neuropathological outcomes JM Long, DW Coble, C Xiong, SE Schindler, RJ Perrin, BA Gordon, ... Brain, 2022 | 30 | 2022 |
Autoimmune dementia JM Long, GS Day Seminars in neurology 38 (03), 303-315, 2018 | 26 | 2018 |
Cognitively normal APOE ε4 carriers have specific elevation of CSF SNAP-25 OH Butt, JM Long, RL Henson, E Herries, CL Sutphen, AM Fagan, ... Neurobiology of aging 102, 64-72, 2021 | 14 | 2021 |
Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy D Toral-Rios, JM Long, JD Ulrich, J Yu, MR Strickland, X Han, ... Rockefeller University Press 221 (4), e20232000, 2024 | 10 | 2024 |
Biochemical evidence for the dysregulation of Alzheimer’s amyloid precursor protein (APP) expression and metabolism in Fragile X syndrome (FXS) and severe autism DK Lahiri, JM Long, B Ray, DK Sokol Society of Biological Psychiatry, 2011 | 5 | 2011 |
P3‐157: A novel microRNA interaction relevant to alzheimer's disease pathogenesis and drug target discovery: miR‐346 induces expression of amyloid precursor protein J Long, D Lahiri Alzheimer's & Dementia 7, S566-S567, 2011 | 3 | 2011 |