Ikuti
Justin Long
Justin Long
Assistant Professor, Washington University School of Medicine
Email yang diverifikasi di wustl.edu
Judul
Dikutip oleh
Dikutip oleh
Tahun
Alzheimer disease: an update on pathobiology and treatment strategies
JM Long, DM Holtzman
Cell 179 (2), 312-339, 2019
26152019
Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model
Y Shi, M Manis, J Long, K Wang, PM Sullivan, J Remolina Serrano, ...
Journal of Experimental Medicine 216 (11), 2546-2561, 2019
3642019
MicroRNA-101 downregulates Alzheimer’s amyloid-β precursor protein levels in human cell cultures and is differentially expressed
JM Long, DK Lahiri
Biochemical and biophysical research communications 404 (4), 889-895, 2011
2622011
MicroRNA-153 physiologically inhibits expression of amyloid-β precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients
JM Long, B Ray, DK Lahiri
Journal of Biological Chemistry 287 (37), 31298-31310, 2012
2322012
MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue …
JM Long, B Ray, DK Lahiri
Journal of Biological Chemistry 289 (8), 5184-5198, 2014
2092014
Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links
DK Sokol, B Maloney, JM Long, B Ray, DK Lahiri
Neurology 76 (15), 1344-1352, 2011
1762011
Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5′-untranslated region: Implications in Alzheimer’s disease
JM Long, B Maloney, JT Rogers, DK Lahiri
Molecular psychiatry 24 (3), 345-363, 2019
1472019
Increased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarker
B Ray, JM Long, DK Sokol, DK Lahiri
PLoS One 6 (6), e20405, 2011
1342011
Lessons from a BACE1 inhibitor trial: off‐site but not off base
DK Lahiri, B Maloney, JM Long, NH Greig
Alzheimer's & Dementia 10, S411-S419, 2014
1082014
Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research
B Ray, N Chopra, JM Long, DK Lahiri
Molecular brain 7 (1), 63, 2014
582014
Select Atrophied Regions in Alzheimer disease (SARA): An improved volumetric model for identifying Alzheimer disease dementia
LN Koenig, GS Day, A Salter, S Keefe, LM Marple, J Long, P LaMontagne, ...
NeuroImage: Clinical, 102248, 2020
532020
Advances in microRNA experimental approaches to study physiological regulation of gene products implicated in CNS disorders
JM Long, DK Lahiri
Experimental neurology 235 (2), 402-418, 2012
472012
Regulation of astrocyte lipid metabolism and ApoE secretion by the microglial oxysterol, 25-hydroxycholesterol
AG Cashikar, D Toral-Rios, D Timm, J Romero, M Strickland, JM Long, ...
Journal of lipid research 64 (4), 2023
372023
Current drug targets for modulating Alzheimer's amyloid precursor protein: role of specific micro-RNA species
JM Long, DK Lahiri
Current medicinal chemistry 18 (22), 3314-3321, 2011
362011
Preclinical Alzheimer’s disease biomarkers accurately predict cognitive and neuropathological outcomes
JM Long, DW Coble, C Xiong, SE Schindler, RJ Perrin, BA Gordon, ...
Brain, 2022
302022
Autoimmune dementia
JM Long, GS Day
Seminars in neurology 38 (03), 303-315, 2018
262018
Cognitively normal APOE ε4 carriers have specific elevation of CSF SNAP-25
OH Butt, JM Long, RL Henson, E Herries, CL Sutphen, AM Fagan, ...
Neurobiology of aging 102, 64-72, 2021
142021
Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy
D Toral-Rios, JM Long, JD Ulrich, J Yu, MR Strickland, X Han, ...
Rockefeller University Press 221 (4), e20232000, 2024
102024
Biochemical evidence for the dysregulation of Alzheimer’s amyloid precursor protein (APP) expression and metabolism in Fragile X syndrome (FXS) and severe autism
DK Lahiri, JM Long, B Ray, DK Sokol
Society of Biological Psychiatry, 2011
52011
P3‐157: A novel microRNA interaction relevant to alzheimer's disease pathogenesis and drug target discovery: miR‐346 induces expression of amyloid precursor protein
J Long, D Lahiri
Alzheimer's & Dementia 7, S566-S567, 2011
32011
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