An engineered CRISPR-Cas12a variant and DNA-RNA hybrid guides enable robust and rapid COVID-19 testing KH Ooi, MM Liu, JWD Tay, SY Teo, P Kaewsapsak, S Jin, CK Lee, J Hou, ... Nature communications 12 (1), 1739, 2021 | 163 | 2021 |
Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells Y Wang, KI Liu, NAB Sutrisnoh, H Srinivasan, J Zhang, J Li, F Zhang, ... Genome biology 19, 1-16, 2018 | 100 | 2018 |
An Expanded Synthetic Biology Toolkit for Gene Expression Control in Acetobacteraceae MY Teh, KH Ooi, SX Danny Teo, ME Bin Mansoor, WZ Shaun Lim, ... ACS synthetic biology 8 (4), 708-723, 2019 | 67 | 2019 |
A sensitive and specific fluorescent RT-LAMP assay for SARS-CoV-2 detection in clinical samples KH Ooi, MM Liu, JR Moo, P Nimsamer, S Payungporn, P Kaewsapsak, ... ACS Synthetic Biology 11 (1), 448-463, 2022 | 22 | 2022 |
A CRISPR-based SARS-CoV-2 diagnostic assay that is robust against viral evolution and RNA editing KH Ooi, JWD Tay, SY Teo, MM Liu, P Kaewsapsak, S Jin, YG Gao, ... bioRxiv, 2020.07. 03.185850, 2020 | 13 | 2020 |
A circularly permuted CasRx platform for efficient, site-specific RNA editing Y Wang, KI Liu, MM Liu, KH Ooi, TA Nguyen, JE Chee, SXD Teo, S He, ... Nature Biotechnology, 1-14, 2024 | | 2024 |
A method for detection of target nucleic acid using isothermal amplification MH Tan, KH Ooi US Patent App. 18/577,860, 2024 | | 2024 |
Programmable rna editing platform MH Tan, W Yuanming, KI Liu, KH Ooi US Patent App. 17/769,047, 2024 | | 2024 |
Truncated CRISPR-Cas proteins for DNA targeting MH Tan, KH Ooi US Patent 11,840,694, 2023 | | 2023 |
Crispr-based methods for the detection of nucleic acids in a sample MH Tan, KH Ooi, JWD Tay, SY Teo US Patent App. 18/003,126, 2023 | | 2023 |
A method for detection of point mutations in target nucleic acid using loop-mediated isothermal amplification MH TAN, KH OOI | | 2023 |
3’end hydrolysis activity of the Bst polymerase enables rapid and sensitive identification of SARS-CoV-2 variants KH Ooi, MM Liu, MSB Burhanudin, S Thirunavukarasu, ZQV Oh, SNS Kwa, ... | | 2023 |
VaNGuard assay protocol for SARS-CoV-2 detection KH Ooi, MM Liu, JWD Tay, SY Teo, P Kaewsapsak, S Jin, CK Lee, J Hou, ... | | 2021 |