| Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells IA Akkouh, T Ueland, L Hansson, E Inderhaug, T Hughes, NE Steen, ... Brain, behavior, and immunity 87, 634-644, 2020 | 61 | 2020 |
| Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway S Wang, JR van Rhijn, I Akkouh, N Kogo, N Maas, A Bleeck, IS Ortiz, ... Cell reports 39 (5), 2022 | 45 | 2022 |
| Lithium increases mitochondrial respiration in iPSC-derived neural precursor cells from lithium responders JR Osete, IA Akkouh, DR de Assis, A Szabo, E Frei, T Hughes, ... Molecular Psychiatry 26 (11), 6789-6805, 2021 | 44 | 2021 |
| Exploring lithium’s transcriptional mechanisms of action in bipolar disorder: a multi-step study IA Akkouh, S Skrede, A Holmgren, KM Ersland, L Hansson, S Bahrami, ... Neuropsychopharmacology 45 (6), 947-955, 2020 | 36 | 2020 |
| Systemic cell adhesion molecules in severe mental illness: potential role of intercellular CAM-1 in linking peripheral and neuroinflammation MA Sheikh, KS O’Connell, T Lekva, A Szabo, IA Akkouh, JR Osete, ... Biological psychiatry 93 (2), 187-196, 2023 | 33 | 2023 |
| Derivation and molecular characterization of a morphological subpopulation of human iPSC astrocytes reveal a potential role in schizophrenia and clozapine response IA Akkouh, H Hribkova, M Grabiec, E Budinska, A Szabo, T Kasparek, ... Schizophrenia bulletin 48 (1), 190-198, 2022 | 29 | 2022 |
| Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia IA Akkouh, T Hughes, VM Steen, JC Glover, OA Andreassen, S Djurovic, ... Brain, behavior, and immunity 94, 235-244, 2021 | 29 | 2021 |
| Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids JR Osete, IA Akkouh, O Ievglevskyi, M Vandenberghe, DR de Assis, ... Molecular Psychiatry 28 (7), 3033-3043, 2023 | 21 | 2023 |
| A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia A Szabo, IA Akkouh, M Vandenberghe, JR Osete, T Hughes, V Heine, ... Translational psychiatry 11 (1), 554, 2021 | 21 | 2021 |
| Expression of TCN1 in Blood is Negatively Associated with Verbal Declarative Memory Performance IA Akkouh, T Ueland, OA Andreassen, HR Brattbakk, VM Steen, T Hughes, ... Scientific reports 8 (1), 12654, 2018 | 17 | 2018 |
| All-optical electrophysiology in hiPSC-derived neurons with synthetic voltage sensors F Puppo, S Sadegh, CA Trujillo, M Thunemann, EP Campbell, ... Frontiers in Cellular Neuroscience 15, 671549, 2021 | 15 | 2021 |
| Elevated systemic levels of markers reflecting intestinal barrier dysfunction and inflammasome activation are correlated in severe mental illness SB Jensen, MA Sheikh, IA Akkouh, A Szabo, KS O’Connell, T Lekva, ... Schizophrenia bulletin 49 (3), 635-645, 2023 | 13 | 2023 |
| Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia KS O'Connell, E Koch, HÇ Lenk, IA Akkouh, G Hindley, P Jaholkowski, ... Psychiatry research 325, 115217, 2023 | 9 | 2023 |
| Dose-dependent transcriptional effects of lithium and adverse effect burden in a psychiatric cohort F Krull, I Akkouh, T Hughes, F Bettella, L Athanasiu, OB Smeland, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 112, 110408, 2022 | 8 | 2022 |
| Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder A Szabo, IA Akkouh, T Ueland, TV Lagerberg, I Dieset, T Bjella, P Aukrust, ... Frontiers in Psychiatry 11, 642, 2020 | 8 | 2020 |
| Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations T Hughes, L Hansson, I Akkouh, R Hajdarevic, JS Bringsli, A Torsvik, ... Scientific Reports 10 (1), 9101, 2020 | 7 | 2020 |
| Cognitive and inflammatory heterogeneity in severe mental illness: Translating findings from blood to brain LS Sæther, A Szabo, IA Akkouh, B Haatveit, C Mohn, A Vaskinn, ... Brain, Behavior, and Immunity 118, 287-299, 2024 | 6 | 2024 |
| Increased ferroptosis in leukocytes from preeclamptic women involving the long non‐coding taurine upregulated gene 1 (TUG1) T Lekva, AE Michelsen, MCP Roland, ER Norwitz, ME Estensen, ... Journal of Internal Medicine 295 (2), 181-195, 2024 | 6 | 2024 |
| Longitudinal transcriptomic analysis of human cortical spheroids identifies axonal dysregulation in the prenatal brain as a mediator of genetic risk for schizophrenia IA Akkouh, T Ueland, A Szabo, T Hughes, OB Smeland, OA Andreassen, ... Biological Psychiatry 95 (7), 687-698, 2024 | 4 | 2024 |
| Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders M Aas, OA Andreassen, J Gjerstad, L Rødevand, G Hjell, IT Johansen, ... Scientific Reports 13 (1), 13845, 2023 | 3 | 2023 |
