The Ins and Outs of Cathepsins: Physiological Function and Role in Disease Management T Yadati, T Houben, A Bitorina, R Shiri-Sverdlov Cells 9 (7), 1679, 2020 | 395 | 2020 |
Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids AWF Janssen, T Houben, S Katiraei, W Dijk, L Boutens, N Van Der Bolt, ... Journal of lipid research 58 (7), 1399-1416, 2017 | 127 | 2017 |
Inflammatory Bowel Disease: A Stressed “Gut/Feeling” Y Oligschlaeger, T Yadati, T Houben, CM Condello Oliván, ... Cells 8 (7), 659, 2019 | 117 | 2019 |
Bone marrow‐specific caspase‐1/11 deficiency inhibits atherosclerosis development in Ldlr−/− mice T Hendrikx, MLJ Jeurissen, PJ van Gorp, MJ Gijbels, SMA Walenbergh, ... The FEBS journal 282 (12), 2327-2338, 2015 | 74 | 2015 |
Cathepsin D regulates lipid metabolism in murine steatohepatitis T Houben, Y Oligschlaeger, T Hendrikx, AV Bitorina, SMA Walenbergh, ... Scientific reports 7 (1), 3494, 2017 | 61 | 2017 |
The immunity–diet–microbiota axis in the development of metabolic syndrome E Brandsma, T Houben, J Fu, R Shiri-Sverdlov, MH Hofker Current opinion in lipidology 26 (2), 73-81, 2015 | 61 | 2015 |
Plasma cathepsin D levels: a novel tool to predict pediatric hepatic inflammation SMA Walenbergh, T Houben, T Hendrikx, MLJ Jeurissen, PJ Van Gorp, ... Official journal of the American College of Gastroenterology| ACG 110 (3 …, 2015 | 53 | 2015 |
Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention SMA Walenbergh, T Houben, SS Rensen, V Bieghs, T Hendrikx, ... Scientific reports 6 (1), 38278, 2016 | 44 | 2016 |
Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr−/− mice T Hendrikx, MLJ Jeurissen, V Bieghs, SMA Walenbergh, PJ van Gorp, ... Journal of hepatology 62 (2), 430-436, 2015 | 33 | 2015 |
Oxidized LDL at the crossroads of immunity in non-alcoholic steatohepatitis T Houben, E Brandsma, SMA Walenbergh, MH Hofker, R Shiri-Sverdlov Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2017 | 32 | 2017 |
Plasma cathepsin D activity rather than levels correlates with metabolic parameters of type 2 diabetes in male individuals L Ding, T Houben, Y Oligschlaeger, AV Bitorina, BJ Verwer, ... Frontiers in Endocrinology 11, 575070, 2020 | 27 | 2020 |
Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague–Dawley Rats P Khurana, T Yadati, S Goyal, A Dolas, T Houben, Y Oligschlaeger, ... Biomolecules 9 (5), 171, 2019 | 27 | 2019 |
Nonalcoholic fatty liver disease L Ding, Y Oligschlaeger, R Shiri-Sverdlov, T Houben Prevention and Treatment of Atherosclerosis: Improving State-of-the-Art …, 2020 | 26 | 2020 |
Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans L Ding, GH Goossens, Y Oligschlaeger, T Houben, EE Blaak, ... Diabetologia 63, 374-384, 2020 | 26 | 2020 |
Weekly treatment of 2-hydroxypropyl-β-cyclodextrin improves intracellular cholesterol levels in LDL receptor knockout mice SMA Walenbergh, T Houben, T Hendrikx, MLJ Jeurissen, PJ Van Gorp, ... International journal of molecular sciences 16 (9), 21056-21069, 2015 | 25 | 2015 |
Blood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammation T Houben, Y Oligschlaeger, AV Bitorina, T Hendrikx, SMA Walenbergh, ... Scientific reports 7 (1), 12550, 2017 | 24 | 2017 |
Prevention of oxLDL uptake leads to decreased atherosclerosis in hematopoietic NPC1-deficient Ldlr−/− mice MLJ Jeurissen, SMA Walenbergh, T Houben, MJJ Gijbels, J Li, T Hendrikx, ... Atherosclerosis 255, 59-65, 2016 | 23 | 2016 |
MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis D Chanda, J Li, Y Oligschlaeger, MLJ Jeurissen, T Houben, ... Experimental & molecular medicine 48 (9), e258-e258, 2016 | 23 | 2016 |
Macrophage stimulating protein enhances hepatic inflammation in a NASH model J Li, D Chanda, PJ van Gorp, MLJ Jeurissen, T Houben, ... PLoS One 11 (9), e0163843, 2016 | 19 | 2016 |
Inhibition of extracellular cathepsin D reduces hepatic lipid accumulation and leads to mild changes in inflammationin NASH mice T Yadati, T Houben, A Bitorina, Y Oligschlaeger, MJ Gijbels, R Mohren, ... Frontiers in immunology 12, 675535, 2021 | 18 | 2021 |