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Tyler Starr
Tyler Starr
Department of Biochemistry, University of Utah
Email yang diverifikasi di biochem.utah.edu - Beranda
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Dikutip oleh
Tahun
Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
TN Starr, AJ Greaney, SK Hilton, D Ellis, KHD Crawford, AS Dingens, ...
Cell 182 (5), 1295-1310. e20, 2020
20482020
Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies
AJ Greaney, AN Loes, KHD Crawford, TN Starr, KD Malone, HY Chu, ...
Cell host & microbe, 2021
12852021
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition
AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein, AN Loes, SK Hilton, ...
Cell host & microbe 29 (1), 44-57. e9, 2021
11432021
Prospective mapping of viral mutations that escape antibodies used to treat COVID-19
TN Starr, AJ Greaney, A Addetia, WW Hannon, MC Choudhary, ...
Science 371 (6531), 850-854, 2021
7892021
Epistasis in protein evolution
TN Starr, JW Thornton
Protein Science, 2016
5332016
Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016
TN Starr, AJ Greaney, AS Dingens, JD Bloom
Cell Reports Medicine 2 (4), 100255, 2021
5112021
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape
TN Starr, N Czudnochowski, Z Liu, F Zatta, YJ Park, A Addetia, D Pinto, ...
Nature 597 (7874), 97-102, 2021
4842021
Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies
AJ Greaney, TN Starr, CO Barnes, Y Weisblum, F Schmidt, M Caskey, ...
Nature Communications 12 (1), 1-14, 2021
431*2021
Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail
J Dong, SJ Zost, AJ Greaney, TN Starr, AS Dingens, EC Chen, RE Chen, ...
Nature Microbiology 6 (10), 1233-1244, 2021
412*2021
Broad sarbecovirus neutralization by a human monoclonal antibody
MA Tortorici, N Czudnochowski, TN Starr, R Marzi, AC Walls, F Zatta, ...
Nature 597 (7874), 103-108, 2021
2492021
Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection
AJ Greaney, AN Loes, LE Gentles, KHD Crawford, TN Starr, KD Malone, ...
Science translational medicine 13 (600), eabi9915, 2021
2472021
Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution
TN Starr, AJ Greaney, WW Hannon, AN Loes, K Hauser, JR Dillen, E Ferri, ...
Science 377 (6604), 420-424, 2022
2262022
Alternative evolutionary histories in the sequence space of an ancient protein
TN Starr, LK Picton, JW Thornton
Nature 549 (7672), 409-413, 2017
2142017
Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models
AA Cohen, N van Doremalen, AJ Greaney, H Andersen, A Sharma, ...
Science 377 (6606), eabq0839, 2022
1922022
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines
AC Walls, MC Miranda, A Schäfer, MN Pham, A Greaney, ...
Cell 184 (21), 5432-5447. e16, 2021
1692021
ACE2 binding is an ancestral and evolvable trait of sarbecoviruses
TN Starr, SK Zepeda, AC Walls, AJ Greaney, S Alkhovsky, D Veesler, ...
Nature 603 (7903), 913-918, 2022
1622022
Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA. 1 and BA. 2 receptor-binding domains
TN Starr, AJ Greaney, CM Stewart, AC Walls, WW Hannon, D Veesler, ...
PLoS pathogens 18 (11), e1010951, 2022
1392022
Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry
YJ Park, A De Marco, TN Starr, Z Liu, D Pinto, AC Walls, F Zatta, ...
Science 375 (6579), 449-454, 2022
1372022
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice
AC Hunt, JB Case, YJ Park, L Cao, K Wu, AC Walls, Z Liu, JE Bowen, ...
Science Translational Medicine, eabn1252, 2022
125*2022
Systematic Mutant Analyses Elucidate General and Client-Specific Aspects of Hsp90 Function
P Mishra, JM Flynn, TN Starr, DNA Bolon
Cell Reports 15 (3), 588-598, 2016
1252016
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