Receptor tyrosine kinases and cancer: oncogenic mechanisms and therapeutic approaches P Saraon, S Pathmanathan, J Snider, A Lyakisheva, V Wong, I Stagljar Oncogene 40 (24), 4079-4093, 2021 | 151 | 2021 |
Diverse epigenetic profile of novel human embryonic stem cell lines MA Lagarkova, PY Volchkov, AV Lyakisheva, ES Philonenko, SL Kiselev Cell cycle 5 (4), 416-420, 2006 | 145 | 2006 |
Split Intein-Mediated Protein Ligation for detecting protein-protein interactions and their inhibition Z Yao, F Aboualizadeh, J Kroll, I Akula, J Snider, A Lyakisheva, P Tang, ... Nature communications 11 (1), 2440, 2020 | 47 | 2020 |
A drug discovery platform to identify compounds that inhibit EGFR triple mutants P Saraon, J Snider, Y Kalaidzidis, LE Wybenga-Groot, K Weiss, A Rai, ... Nature chemical biology 16 (5), 577-586, 2020 | 42 | 2020 |
Paroxysmal nocturnal hemoglobinuria: differential gene expression of EGR-1 and TAXREB107 A Lyakisheva, O Felda, A Ganser, RE Schmidt, J Schubert Experimental hematology 30 (1), 18-25, 2002 | 39 | 2002 |
CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system SH Lim, J Snider, L Birimberg‐Schwartz, W Ip, JC Serralha, HM Botelho, ... Molecular systems biology 18 (2), e10629, 2022 | 28 | 2022 |
Drugging the undruggable proteins in cancer: A systems biology approach S Pathmanathan, I Grozavu, A Lyakisheva, I Stagljar Current opinion in chemical biology 66, 102079, 2022 | 28 | 2022 |
Homogeneous surrogate virus neutralization assay to rapidly assess neutralization activity of anti-SARS-CoV-2 antibodies SJ Kim, Z Yao, MC Marsh, DM Eckert, MS Kay, A Lyakisheva, M Pasic, ... Nature communications 13 (1), 3716, 2022 | 23 | 2022 |
MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis VV Phadnis, J Snider, V Varadharajan, I Ramachandiran, AA Deik, ... Cell reports 42 (9), 2023 | 22 | 2023 |
D154Q mutation does not alter KRAS dimerization I Grozavu, S Stuart, A Lyakisheva, Z Yao, S Pathmanathan, M Ohh, ... Journal of molecular biology 434 (2), 167392, 2022 | 17 | 2022 |
Chemical genetics screen identifies COPB2 tool compounds that alters ER stress response and induces RTK dysregulation in lung cancer cells P Saraon, J Snider, W Schormann, A Rai, N Radulovich, ... Journal of molecular biology 433 (23), 167294, 2021 | 12 | 2021 |
Characteristics of human bone marrow mesenchymal stem cells isolated by immunomagnetic selection MA Lagar’kova, AV Lyakisheva, ES Filonenko, PY Volchkov, KV Rubtsova, ... Bulletin of Experimental Biology and Medicine 141, 112-116, 2006 | 12 | 2006 |
Quantum computing-enhanced algorithm unveils novel inhibitors for KRAS MG Vakili, C Gorgulla, AK Nigam, D Bezrukov, D Varoli, A Aliper, ... arXiv preprint arXiv:2402.08210, 2024 | 11 | 2024 |
A split intein and split luciferase-coupled system for detecting protein-protein interactions Z Yao, J Kim, B Geng, J Chen, V Wong, A Lyakisheva, J Snider, ... Molecular Systems Biology, 1-19, 2024 | 1 | 2024 |
Abstract A37: Mapping KRAS signaling pathways using the Mammalian-Membrane Two-Hybrid (MaMTH) assay to elucidate novel therapeutic targets IC Grozavu, J Snider, A Lyakisheva, I Stagljar Molecular Cancer Research 18 (5_Supplement), A37-A37, 2020 | 1 | 2020 |
Quantum-computing-enhanced algorithm unveils potential KRAS inhibitors M Ghazi Vakili, C Gorgulla, J Snider, AK Nigam, D Bezrukov, D Varoli, ... Nature Biotechnology, 1-6, 2025 | | 2025 |
Quantum Computing-Enhanced Algorithm Unveils Novel Inhibitors for KRAS M Ghazi Vakili, C Gorgulla, AK Nigam, D Bezrukov, D Varoli, A Aliper, ... arXiv e-prints, arXiv: 2402.08210, 2024 | | 2024 |
Elucidating Met receptor tyrosine kinase interactome to identify novel regulators of Met biology S Pathmanathan University of Toronto (Canada), 2022 | | 2022 |
Investigating the Dynamic CFTR Interactome using the Mammalian Membrane Two-Hybrid (MaMTH) platform SH Lim University of Toronto (Canada), 2021 | | 2021 |
Mapping KRAS signaling pathways using the Mammalian-Membrane Two-Hybrid (MaMTH) assay to elucidate novel therapeutic targets. IC Grozavu, J Snider, A Lyakisheva, I Stagljar MOLECULAR CANCER RESEARCH 18 (5), 49-49, 2020 | | 2020 |