Ikuti
Leland Taylor
Leland Taylor
National Human Genome Research Institute - University of Cambridge
Email yang diverifikasi di nih.gov - Beranda
Judul
Dikutip oleh
Dikutip oleh
Tahun
Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
SCJ Parker, ML Stitzel, DL Taylor, JM Orozco, MR Erdos, JA Akiyama, ...
Proceedings of the National Academy of Sciences 110 (44), 17921-17926, 2013
741*2013
Genetic regulatory signatures underlying islet gene expression and type 2 diabetes
A Varshney, LJ Scott, RP Welch, MR Erdos, PS Chines, N Narisu, ...
Proceedings of the National Academy of Sciences 114 (9), 2301-2306, 2017
2132017
The genetic regulatory signature of type 2 diabetes in human skeletal muscle
LJ Scott, MR Erdos, JR Huyghe, RP Welch, AT Beck, BN Wolford, ...
Nature communications 7 (1), 11764, 2016
1412016
Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle
DL Taylor, AU Jackson, N Narisu, G Hemani, MR Erdos, PS Chines, ...
Proceedings of the National Academy of Sciences 116 (22), 10883-10888, 2019
1372019
BoostMe accurately predicts DNA methylation values in whole-genome bisulfite sequencing of multiple human tissues
LS Zou, MR Erdos, DL Taylor, PS Chines, A Varshney, ...
BMC genomics 19, 1-15, 2018
452018
Calcification of the abdominal aorta is an under-appreciated cardiovascular disease risk factor in the general population
A Sethi, DL Taylor, JG Ruby, J Venkataraman, E Sorokin, M Cule, ...
Frontiers in Cardiovascular Medicine 9, 1003246, 2022
26*2022
Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis
HJ Taylor, YH Hung, N Narisu, MR Erdos, M Kanke, T Yan, CM Grenko, ...
Proceedings of the National Academy of Sciences 120 (7), e2206797120, 2023
222023
Interactions between genetic variation and cellular environment in skeletal muscle gene expression
DL Taylor, DA Knowles, LJ Scott, AH Ramirez, FP Casale, BN Wolford, ...
PLoS One 13 (4), e0195788, 2018
212018
Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells
D Xue, N Narisu, DL Taylor, M Zhang, C Grenko, HJ Taylor, T Yan, X Tang, ...
Cell Metabolism 35 (11), 1897-1914. e11, 2023
182023
The promise and reality of therapeutic discovery from large cohorts
E Melamud, DL Taylor, A Sethi, M Cule, A Baryshnikova, D Saleheen, ...
The Journal of Clinical Investigation 130 (2), 575-581, 2020
102020
Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits
S Hudaiberdiev, DL Taylor, W Song, N Narisu, RM Bhuiyan, HJ Taylor, ...
Proceedings of the National Academy of Sciences 120 (35), e2206612120, 2023
52023
Bacterial Logic Devices Reveal Unexpected Behavior of Frameshift Suppressor tRNAs
EM Sawyer, C Barta, R Clemente, M Conn, C Davis, C Doyle, M Gearing, ...
Interdisciplinary Bio Central 4 (10), 2012
52012
Illuminating the Black Box of Genome Sequence Assembly: A Free Online Tool to Introduce Students to Bioinformatics
DL Taylor, AM Campbell, LJ Heyer
The American Biology Teacher 75 (8), 572-577, 2013
32013
An integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D associated genes and regulatory signals
Z Zhao, RDO Albanus, H Taylor, X Tang, Y Han, P Orchard, A Varshney, ...
Research Square, 2023
22023
Single-cell RNA sequencing reveals dysregulated cellular programmes in the inflamed epithelium of Crohn’s disease patients
M Krzak, T Alegbe, DL Taylor, M Ghouraba, M Strickland, R Satti, ...
medRxiv, 2023.09. 06.23295056, 2023
22023
Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h
CM Grenko, HJ Taylor, LL Bonnycastle, D Xue, BN Lee, Z Weiss, T Yan, ...
Diabetologia 67 (10), 2246-2259, 2024
12024
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