Ikuti
Isabelle Capell-Hattam
Isabelle Capell-Hattam
Email yang diverifikasi di unsw.edu.au
Judul
Dikutip oleh
Dikutip oleh
Tahun
Oxysterols: old tale, new twists
W Luu, LJ Sharpe, I Capell-Hattam, IC Gelissen, AJ Brown
Annual review of pharmacology and toxicology 56 (1), 447-467, 2016
1572016
The cholesterol synthesis enzyme lanosterol 14α-demethylase is post-translationally regulated by the E3 ubiquitin ligase MARCH6
NA Scott, LJ Sharpe, IM Capell-Hattam, SJ Gullo, W Luu, AJ Brown
Biochemical Journal 477 (2), 541-555, 2020
322020
The mammalian cholesterol synthesis enzyme squalene monooxygenase is proteasomally truncated to a constitutively active form
HW Coates, IM Capell-Hattam, AJ Brown
Journal of Biological Chemistry 296, 2021
262021
Twin enzymes, divergent control: The cholesterogenic enzymes DHCR14 and LBR are differentially regulated transcriptionally and post-translationally
IM Capell-Hattam, LJ Sharpe, L Qian, G Hart-Smith, AV Prabhu, AJ Brown
Journal of Biological Chemistry 295 (9), 2850-2865, 2020
262020
Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase
HW Coates, IM Capell-Hattam, EM Olzomer, X Du, R Farrell, H Yang, ...
Elife 12, e82843, 2023
162023
Sterol evolution: cholesterol synthesis in animals is less a required trait than an acquired taste
IM Capell-Hattam, AJ Brown
Current Biology 30 (15), R886-R888, 2020
152020
Cholesterol synthesis enzyme SC4MOL is fine-tuned by sterols and targeted for degradation by the E3 ligase MARCHF6
L Qian, NA Scott, IM Capell-Hattam, EA Draper, NM Fenton, W Luu, ...
Journal of Lipid Research 64 (5), 100362, 2023
132023
The non catalytic protein ERG28 has a functional role in cholesterol synthesis and is coregulated transcriptionally
IM Capell-Hattam, NM Fenton, HW Coates, LJ Sharpe, AJ Brown
Journal of Lipid Research 63 (12), 100295, 2022
112022
Cholesterol synthesis unleashed: hypoxia induces the proteasomal truncation and constitutive activation of squalene monooxygenase
H Coates, I Capell-Hattam, A Brown
FEBS OPEN BIO 12, 59-60, 2022
2022
A new kid in the Bloch? The non-catalytic protein ERG28 plays a functional role in mammalian cholesterol synthesis and is co-regulated transcriptionally
IM Capell-Hattam, NM Fenton, LJ Sharpe, AJ Brow
FEBS OPEN BIO 12, 267-267, 2022
2022
Spotlighting two neglected components in cholesterol biosynthesis
IM Capell-Hattam
PQDT-Global, 2022
2022
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