Ikuti
Michael L. Stitzel
Michael L. Stitzel
Associate Professor, The Jackson Laboratory for Genomic Medicine
Email yang diverifikasi di jax.org
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Dikutip oleh
Dikutip oleh
Tahun
The genetic architecture of type 2 diabetes
C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ...
Nature 536 (7614), 41-47, 2016
13102016
Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
SCJ Parker, ML Stitzel, DL Taylor, JM Orozco, MR Erdos, JA Akiyama, ...
Proceedings of the National Academy of Sciences 110 (44), 17921-17926, 2013
7202013
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type–specific expression changes in type 2 diabetes
N Lawlor, J George, M Bolisetty, R Kursawe, L Sun, V Sivakamasundari, ...
Genome research 27 (2), 208-222, 2017
5322017
Regulation of the oocyte-to-zygote transition
ML Stitzel, G Seydoux
Science 316 (5823), 407-408, 2007
3222007
Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci
ML Stitzel, P Sethupathy, DS Pearson, PS Chines, L Song, MR Erdos, ...
Cell metabolism 12 (5), 443-455, 2010
2352010
Targeted disruption of the methionine synthase gene in mice
DA Swanson, ML Liu, PJ Baker, L Garrett, M Stitzel, J Wu, M Harris, ...
Molecular and cellular biology, 2001
2142001
Genetic regulatory signatures underlying islet gene expression and type 2 diabetes
A Varshney, LJ Scott, RP Welch, MR Erdos, PS Chines, N Narisu, ...
Proceedings of the National Academy of Sciences 114 (9), 2301-2306, 2017
2132017
Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma
JJ Gartner, SCJ Parker, TD Prickett, K Dutton-Regester, ML Stitzel, JC Lin, ...
Proceedings of the National Academy of Sciences 110 (33), 13481-13486, 2013
2002013
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
AR Majithia, J Flannick, P Shahinian, M Guo, MA Bray, P Fontanillas, ...
Proceedings of the National Academy of Sciences 111 (36), 13127-13132, 2014
1912014
The chromatin accessibility signature of human immune aging stems from CD8+ T cells
D Ucar, EJ Márquez, CH Chung, R Marches, RJ Rossi, A Uyar, TC Wu, ...
Journal of Experimental Medicine 214 (10), 3123-3144, 2017
1822017
Autosomal dominant diabetes arising from a Wolfram syndrome 1 mutation
LL Bonnycastle, PS Chines, T Hara, JR Huyghe, AJ Swift, P Heikinheimo, ...
Diabetes 62 (11), 3943-3950, 2013
1312013
The C. elegans DYRK kinase MBK-2 marks oocyte proteins for degradation in response to meiotic maturation
ML Stitzel, J Pellettieri, G Seydoux
Current Biology 16 (1), 56-62, 2006
1262006
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D
A Viñuela, A Varshney, M van de Bunt, RB Prasad, O Asplund, A Bennett, ...
Nature communications 11 (1), 4912, 2020
1192020
A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell
JR Kulzer, ML Stitzel, MA Morken, JR Huyghe, C Fuchsberger, J Kuusisto, ...
The American Journal of Human Genetics 94 (2), 186-197, 2014
1022014
National Institutes of Health Intramural Sequencing Center Comparative Sequencing Program Authors; NISC Comparative Sequencing Program Authors (2013). Chromatin stretch …
SC Parker, ML Stitzel, DL Taylor, JM Orozco, MR Erdos, JA Akiyama, ...
Proc. Natl. Acad. Sci. USA 110, 17921-17926, 0
79
Multiomic profiling identifies cis-regulatory networks underlying human pancreatic β cell identity and function
N Lawlor, EJ Marquez, P Orchard, N Narisu, MS Shamim, A Thibodeau, ...
Cell reports 26 (3), 788-801. e6, 2019
772019
Type 2 diabetes–associated genetic variants regulate chromatin accessibility in human islets
S Khetan, R Kursawe, A Youn, N Lawlor, A Jillette, EJ Marquez, D Ucar, ...
Diabetes 67 (11), 2466-2477, 2018
762018
Genomics of islet (dys) function and type 2 diabetes
N Lawlor, S Khetan, D Ucar, ML Stitzel
Trends in Genetics 33 (4), 244-255, 2017
752017
Regulation of MBK-2/Dyrk kinase by dynamic cortical anchoring during the oocyte-to-zygote transition
ML Stitzel, KCC Cheng, G Seydoux
Current Biology 17 (18), 1545-1554, 2007
722007
A Type 2 Diabetes–Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the ADCY5 Locus
TS Roman, ME Cannon, S Vadlamudi, ML Buchkovich, BN Wolford, ...
Diabetes 66 (9), 2521-2530, 2017
712017
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