Sp1 transcription factor: A long-standing target in cancer chemotherapy C Vizcaíno, S Mansilla, J Portugal Pharmacology & therapeutics 152, 111-124, 2015 | 407 | 2015 |
Assignment of DNA binding sites for 4′, 6-diamidine-2-phenylindole and bisbenzimide (Hoechst 33258). A comparative footprinting study J Portugal, MJ Waring Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 949 (2 …, 1988 | 311 | 1988 |
The antimalarial and cytotoxic drug cryptolepine intercalates into DNA at cytosine-cytosine sites JN Lisgarten, M Coll, J Portugal, CW Wright, J Aymami Nature Structural & Molecular Biology 9 (1), 57, 2002 | 265 | 2002 |
Mitotic catastrophe results in cell death by caspase-dependentand caspase-independent mechanisms S Mansilla, W Priebe, J Portugal Cell Cycle 5 (1), 53-60, 2006 | 167 | 2006 |
Mechanisms of drug-induced mitotic catastrophe in cancer cells J Portugal, S Mansilla, M Bataller Current pharmaceutical design 16 (1), 69-78, 2010 | 156 | 2010 |
Comparison of binding sites in DNA for berenil, netropsin and distamycin: a footprinting study J PORTUGAL, MJ WARING European journal of biochemistry 167 (2), 281-289, 1987 | 150 | 1987 |
Thermodynamic characterization of the multivalent binding of chartreusin to DNA F Barceló, D Capó, J Portugal Nucleic acids research 30 (20), 4567-4573, 2002 | 104 | 2002 |
Mitotic catastrophe as a consequence of chemotherapy S Mansilla, M Bataller, J Portugal Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2006 | 89 | 2006 |
Bisanthracycline WP631 inhibits basal and Sp1-activated transcription initiation in vitro B Martín, A Vaquero, W Priebe, J Portugal Nucleic acids research 27 (17), 3402-3409, 1999 | 87 | 1999 |
T7 RNA polymerase cannot transcribe through a highly knotted DNA template J Portugal, A Rodríguez-Campos Nucleic acids research 24 (24), 4890-4894, 1996 | 87 | 1996 |
A new bisintercalating anthracycline with picomolar DNA binding affinity J Portugal, DJ Cashman, JO Trent, N Ferrer-Miralles, T Przewloka, I Fokt, ... Journal of medicinal chemistry 48 (26), 8209-8219, 2005 | 82 | 2005 |
Hydroxyl radical footprinting of the sequence-selective binding of netropsin and distamycin to DNA J Portugal, MJ Waring FEBS letters 225 (1-2), 195-200, 1987 | 81 | 1987 |
Cell death pathways in response to antitumor therapy J Portugal, M Bataller, S Mansilla Tumori Journal 95 (4), 409-421, 2009 | 77 | 2009 |
Daunorubicin-induced variations in gene transcription: commitment to proliferation arrest, senescence and apoptosis S Mansilla, B Piña, J Portugal Biochemical Journal 372 (3), 703-711, 2003 | 66 | 2003 |
DNA binding characteristics of mithramycin and chromomycin analogues obtained by combinatorial biosynthesis F Barceló, M Ortiz-Lombardía, M Martorell, M Oliver, C Méndez, JA Salas, ... Biochemistry 49 (49), 10543-10552, 2010 | 63 | 2010 |
Chemotherapeutic targeting of cell death pathways S Mansilla, L Llovera, J Portugal Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2012 | 62 | 2012 |
Entropically-driven binding of mithramycin in the minor groove of C/G-rich DNA sequences F Barceló, C Scotta, M Ortiz-Lombardía, C Méndez, JA Salas, J Portugal Nucleic acids research 35 (7), 2215-2226, 2007 | 62 | 2007 |
Analysis of the effects of daunorubicin and WP631 on transcription J Portugal, B Martin, A Vaquero, N Ferrer, S Villamarin, W Priebe Current medicinal chemistry 8 (1), 1-8, 2001 | 62 | 2001 |
Diethyl pyrocarbonate can detect a modified DNA structure induced by the binding of quinoxaline antibioties J Portugal, KR Fox, MJ McLean, JL Richenberg, MJ Waring Nucleic acids research 16 (9), 3655-3670, 1988 | 61 | 1988 |
Chartreusin, elsamicin A and related anti-cancer antibiotics J Portugal Current Medicinal Chemistry-Anti-Cancer Agents 3 (6), 411-420, 2003 | 60 | 2003 |