Dissecting the mycobacterial cell envelope and defining the composition of the native mycomembrane L Chiaradia, C Lefebvre, J Parra, J Marcoux, O Burlet-Schiltz, G Etienne, ... Scientific reports 7 (1), 12807, 2017 | 313 | 2017 |
Structure of the TatC core of the twin-arginine protein transport system SE Rollauer, MJ Tarry, JE Graham, M Jääskeläinen, F Jäger, S Johnson, ... Nature 492 (7428), 210-214, 2012 | 216 | 2012 |
Twenty years of gas phase structural biology J Marcoux, CV Robinson Structure 21 (9), 1541-1550, 2013 | 193 | 2013 |
Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump J Marcoux, SC Wang, A Politis, E Reading, J Ma, PC Biggin, M Zhou, ... Proceedings of the National Academy of Sciences 110 (24), 9704-9709, 2013 | 192 | 2013 |
A novel mechano‐enzymatic cleavage mechanism underlies transthyretin amyloidogenesis J Marcoux, PP Mangione, R Porcari, MT Degiacomi, G Verona, GW Taylor, ... EMBO molecular medicine 7 (10), 1337-1349, 2015 | 167 | 2015 |
NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action V Jaquet, J Marcoux, E Forest, KG Leidal, S McCormick, Y Westermaier, ... British journal of pharmacology 164 (2b), 507-520, 2011 | 148 | 2011 |
Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins SC Lee, BC Bennett, WX Hong, Y Fu, KA Baker, J Marcoux, CV Robinson, ... Proceedings of the National Academy of Sciences 110 (13), E1203-E1211, 2013 | 145 | 2013 |
Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine‐linked antibody drug conjugate J Marcoux, T Champion, O Colas, E Wagner‐Rousset, N Corvaïa, ... Protein Science 24 (8), 1210-1223, 2015 | 142 | 2015 |
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis PP Mangione, R Porcari, JD Gillmore, P Pucci, M Monti, M Porcari, ... Proceedings of the National Academy of Sciences 111 (4), 1539-1544, 2014 | 137 | 2014 |
Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells R Planès, M Pinilla, K Santoni, A Hessel, C Passemar, K Lay, P Paillette, ... Molecular cell 82 (13), 2385-2400. e9, 2022 | 119 | 2022 |
Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates A Beck, G Terral, F Debaene, E Wagner-Rousset, J Marcoux, ... Expert review of proteomics 13 (2), 157-183, 2016 | 114 | 2016 |
Charge reduction stabilizes intact membrane protein complexes for mass spectrometry S Mehmood, J Marcoux, JTS Hopper, TM Allison, I Liko, AJ Borysik, ... Journal of the American Chemical Society 136 (49), 17010-17012, 2014 | 103 | 2014 |
Plasminogen activation triggers transthyretin amyloidogenesis in vitro PP Mangione, G Verona, A Corazza, J Marcoux, D Canetti, S Giorgetti, ... Journal of Biological Chemistry 293 (37), 14192-14199, 2018 | 96 | 2018 |
Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24 S Mehmood, J Marcoux, J Gault, A Quigley, S Michaelis, SG Young, ... Nature chemistry 8 (12), 1152-1158, 2016 | 73 | 2016 |
Characterisation of Shigella Spa33 and Thermotoga FliM/N reveals a new model for C‐ring assembly in T3SS MA McDowell, J Marcoux, G McVicker, S Johnson, YH Fong, R Stevens, ... Molecular microbiology 99 (4), 749-766, 2016 | 73 | 2016 |
Mass spectrometry defines the C-terminal dimerization domain and enables modeling of the structure of full-length OmpA J Marcoux, A Politis, D Rinehart, DP Marshall, MI Wallace, LK Tamm, ... Structure 22 (5), 781-790, 2014 | 66 | 2014 |
p47phox molecular activation for assembly of the neutrophil NADPH oxidase complex J Marcoux, P Man, I Petit-Haertlein, C Vivès, E Forest, F Fieschi Journal of Biological Chemistry 285 (37), 28980-28990, 2010 | 66 | 2010 |
Native desorption electrospray ionization liberates soluble and membrane protein complexes from surfaces S Ambrose, NG Housden, K Gupta, J Fan, P White, HY Yen, J Marcoux, ... Angewandte Chemie 129 (46), 14655-14660, 2017 | 61 | 2017 |
Human Stress-inducible Hsp70 Has a High Propensity to Form ATP-dependent Antiparallel Dimers That Are Differentially Regulated by Cochaperone Binding*[S] F Trcka, M Durech, P Vankova, J Chmelik, V Martinkova, J Hausner, ... Molecular & Cellular Proteomics 18 (2), 320-337, 2019 | 51 | 2019 |
Investigating alternative acidic proteases for H/D exchange coupled to mass spectrometry: plasmepsin 2 but not plasmepsin 4 is active under quenching conditions J Marcoux, E Thierry, C Vivès, L Signor, F Fieschi, E Forest Journal of the American Society for Mass Spectrometry 21, 76-79, 2010 | 47 | 2010 |