Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ... The Lancet 397 (10269), 99-111, 2021 | 5747 | 2021 |
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four … M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ... The Lancet 397 (10277), 881-891, 2021 | 1427 | 2021 |
An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28 DR Owen, AJ Yeo, RN Gunn, K Song, G Wadsworth, A Lewis, C Rhodes, ... Journal of Cerebral Blood Flow & Metabolism 32 (1), 1-5, 2012 | 835 | 2012 |
Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [11C]PBR28 PET Brain Imaging Study PS Bloomfield, S Selvaraj, M Veronese, G Rizzo, A Bertoldo, DR Owen, ... American Journal of Psychiatry 173 (1), 44-52, 2016 | 507 | 2016 |
Roles of microglia in brain development, tissue maintenance and repair MA Michell-Robinson, H Touil, LM Healy, DR Owen, BA Durafourt, ... Brain 138 (5), 1138-1159, 2015 | 453 | 2015 |
Mixed-affinity binding in humans with 18-kDa translocator protein ligands DRJ Owen, RN Gunn, EA Rabiner, I Bennacef, M Fujita, WC Kreisl, ... Journal of nuclear medicine 52 (1), 24-32, 2011 | 431 | 2011 |
Phagocytosis in the brain: homeostasis and disease DA Galloway, AEM Phillips, DRJ Owen, CS Moore Frontiers in immunology 10, 790, 2019 | 337 | 2019 |
Imaging intraplaque inflammation in carotid atherosclerosis with 11C-PK11195 positron emission tomography/computed tomography O Gaemperli, J Shalhoub, DRJ Owen, F Lamare, S Johansson, N Fouladi, ... European heart journal 33 (15), 1902-1910, 2012 | 304 | 2012 |
Two Binding Sites for [3H]PBR28 in Human Brain: Implications for TSPO PET Imaging of Neuroinflammation DR Owen, OW Howell, SP Tang, LA Wells, I Bennacef, M Bergstrom, ... Journal of Cerebral Blood Flow & Metabolism 30 (9), 1608-1618, 2010 | 248 | 2010 |
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell stem cell 29 (2), 217-231. e8, 2022 | 215 | 2022 |
Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans DR Owen, N Narayan, L Wells, L Healy, E Smyth, EA Rabiner, ... Journal of Cerebral Blood Flow & Metabolism 37 (8), 2679-2690, 2017 | 211 | 2017 |
Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration G Scott, H Zetterberg, A Jolly, JH Cole, S De Simoni, PO Jenkins, ... Brain 141 (2), 459-471, 2018 | 199 | 2018 |
PET imaging of neuroinflammation in neurological disorders WC Kreisl, MJ Kim, JM Coughlin, ID Henter, DR Owen, RB Innis The Lancet Neurology 19 (11), 940-950, 2020 | 182 | 2020 |
Imaging of atherosclerosis DRJ Owen, AC Lindsay, RP Choudhury, ZA Fayad Annual review of medicine 62 (1), 25-40, 2011 | 168 | 2011 |
Medical consequences of pathogenic CNVs in adults: analysis of the UK Biobank K Crawford, M Bracher-Smith, D Owen, KM Kendall, E Rees, AF Pardiñas, ... Journal of Medical Genetics 56 (3), 131-138, 2019 | 167 | 2019 |
Hippocampal neuroinflammation, functional connectivity, and depressive symptoms in multiple sclerosis A Colasanti, Q Guo, P Giannetti, MB Wall, RD Newbould, C Bishop, ... Biological psychiatry 80 (1), 62-72, 2016 | 157 | 2016 |
Determination of [11C]PBR28 Binding Potential in vivo: A First Human TSPO Blocking Study DR Owen, Q Guo, NJ Kalk, A Colasanti, D Kalogiannopoulou, R Dimber, ... Journal of Cerebral Blood Flow & Metabolism 34 (6), 989-994, 2014 | 150 | 2014 |
Inflammation within carotid atherosclerotic plaque: assessment with late-phase contrast-enhanced US DR Owen, J Shalhoub, S Miller, T Gauthier, O Doryforou, AH Davies, ... Radiology 255 (2), 638-644, 2010 | 136 | 2010 |
Cellular sources of TSPO expression in healthy and diseased brain E Nutma, K Ceyzériat, S Amor, S Tsartsalis, P Millet, DR Owen, ... European journal of nuclear medicine and molecular imaging, 1-18, 2021 | 135 | 2021 |
Diverse human astrocyte and microglial transcriptional responses to Alzheimer’s pathology AM Smith, K Davey, S Tsartsalis, C Khozoie, N Fancy, SS Tang, E Liaptsi, ... Acta Neuropathologica 143 (1), 75-91, 2022 | 132 | 2022 |