BrafV600E cooperates with Pten loss to induce metastatic melanoma D Dankort, DP Curley, RA Cartlidge, B Nelson, AN Karnezis, ... Nature genetics 41 (5), 544-552, 2009 | 1403 | 2009 |
A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors D Dankort, E Filenova, M Collado, M Serrano, K Jones, M McMahon Genes & development 21 (4), 379-384, 2007 | 604 | 2007 |
β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas WE Damsky, DP Curley, M Santhanakrishnan, LE Rosenbaum, JT Platt, ... Cancer cell 20 (6), 741-754, 2011 | 432 | 2011 |
A central role for RAF→ MEK→ ERK signaling in the genesis of pancreatic ductal adenocarcinoma EA Collisson, CL Trejo, JM Silva, S Gu, JE Korkola, LM Heiser, ... Cancer discovery 2 (8), 685-693, 2012 | 365 | 2012 |
Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis LCW Vredeveld, PA Possik, MA Smit, K Meissl, C Michaloglou, ... Genes & development 26 (10), 1055-1069, 2012 | 328 | 2012 |
Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity SK Muthuswamy, PM Siegel, DL Dankort, MA Webster, WJ Muller Molecular and cellular biology 14 (1), 735-743, 1994 | 302 | 1994 |
Novel Activating Mutations in the neu Proto-oncogene Involved in Induction of Mammary Tumors PM Siegel, DL Dankort, WR Hardy, WJ Muller Molecular and cellular biology 14 (11), 7068-7077, 1994 | 298 | 1994 |
Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer D Dankort, B Maslikowski, N Warner, N Kanno, H Kim, Z Wang, MF Moran, ... Molecular and cellular biology 21 (5), 1540-1551, 2001 | 229 | 2001 |
Distinct tyrosine autophosphorylation sites negatively and positively modulate neu-mediated transformation DL Dankort, Z Wang, V Blackmore, MF Moran, WJ Muller Molecular and cellular biology 17 (9), 5410-5425, 1997 | 195 | 1997 |
Memo mediates ErbB2-driven cell motility R Marone, D Hess, D Dankort, WJ Muller, NE Hynes, A Badache Nature cell biology 6 (6), 515-522, 2004 | 166 | 2004 |
Functional relevance of the histone γH2Ax in the response to DNA damaging agents I Revet, L Feeney, S Bruguera, W Wilson, TK Dong, DH Oh, D Dankort, ... Proceedings of the National Academy of Sciences 108 (21), 8663-8667, 2011 | 157 | 2011 |
HGF converts ErbB2/Neu epithelial morphogenesis to cell invasion H Khoury, MA Naujokas, D Zuo, V Sangwan, MM Frigault, S Petkiewicz, ... Molecular biology of the cell 16 (2), 550-561, 2005 | 157 | 2005 |
mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation W Damsky, G Micevic, K Meeth, V Muthusamy, DP Curley, ... Cancer cell 27 (1), 41-56, 2015 | 144 | 2015 |
Characterization of melanoma cells capable of propagating tumors from a single cell MA Held, DP Curley, D Dankort, M McMahon, V Muthusamy, ... Cancer research 70 (1), 388-397, 2010 | 142 | 2010 |
Signal transduction in mammary tumorigenesis: a transgenic perspective DL Dankort, WJ Muller Oncogene 19 (8), 1038-1044, 2000 | 135 | 2000 |
Mutationally activated BRAFV600E elicits papillary thyroid cancer in the adult mouse RP Charles, G Iezza, E Amendola, D Dankort, M McMahon Cancer research 71 (11), 3863-3871, 2011 | 126 | 2011 |
Multiple ErbB-2/Neu phosphorylation sites mediate transformation through distinct effector proteins D Dankort, N Jeyabalan, N Jones, DJ Dumont, WJ Muller Journal of Biological Chemistry 276 (42), 38921-38928, 2001 | 125 | 2001 |
B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer J Wang, T Kobayashi, N Floc'h, CW Kinkade, A Aytes, D Dankort, ... Cancer research 72 (18), 4765-4776, 2012 | 113 | 2012 |
The Shc adaptor protein is critical for VEGF induction by Met/HGF and ErbB2 receptors and for early onset of tumor angiogenesis C Saucier, H Khoury, KMV Lai, P Peschard, D Dankort, MA Naujokas, ... Proceedings of the National Academy of Sciences 101 (8), 2345-2350, 2004 | 106 | 2004 |
The c-Src tyrosine kinase associates with the catalytic domain of ErbB-2: implications for ErbB-2 mediated signaling and transformation H Kim, R Chan, DL Dankort, D Zuo, M Najoukas, M Park, WJ Muller Oncogene 24 (51), 7599-7607, 2005 | 92 | 2005 |