Mitochondrial degeneration precedes the development of muscle atrophy in progression of cancer cachexia in tumour‐bearing mice JL Brown, ME Rosa‐Caldwell, DE Lee, TA Blackwell, LA Brown, RA Perry, ... Journal of cachexia, sarcopenia and muscle 8 (6), 926-938, 2017 | 288 | 2017 |
Mitochondrial quality control, promoted by PGC‐1α, is dysregulated by Western diet‐induced obesity and partially restored by moderate physical activity in mice NP Greene, DE Lee, JL Brown, ME Rosa, LA Brown, RA Perry, JN Henry, ... Physiological reports 3 (7), e12470, 2015 | 205 | 2015 |
Protein imbalance in the development of skeletal muscle wasting in tumour‐bearing mice JL Brown, DE Lee, ME Rosa‐Caldwell, LA Brown, RA Perry, WS Haynie, ... Journal of cachexia, sarcopenia and muscle 9 (5), 987-1002, 2018 | 110 | 2018 |
microRNA‐16 is downregulated during insulin resistance and controls skeletal muscle protein accretion DE Lee, JL Brown, ME Rosa, LA Brown, RA Perry Jr, MP Wiggs, ... Journal of cellular biochemistry 117 (8), 1775-1787, 2016 | 74 | 2016 |
Diet‐induced obesity alters anabolic signalling in mice at the onset of skeletal muscle regeneration LA Brown, DE Lee, JF Patton, RA Perry Jr, JL Brown, JI Baum, ... Acta physiologica 215 (1), 46-57, 2015 | 68 | 2015 |
Moderate physical activity promotes basal hepatic autophagy in diet-induced obese mice ME Rosa-Caldwell, DE Lee, JL Brown, LA Brown, RA Perry Jr, ES Greene, ... Applied Physiology, Nutrition, and Metabolism 42 (2), 148-156, 2017 | 67 | 2017 |
Cancer cachexia-induced muscle atrophy: evidence for alterations in microRNAs important for muscle size DE Lee, JL Brown, ME Rosa-Caldwell, TA Blackwell, RA Perry Jr, ... Physiological genomics 49 (5), 253-260, 2017 | 66 | 2017 |
Development and progression of cancer cachexia: Perspectives from bench to bedside S Lim, JL Brown, TA Washington, NP Greene Sports medicine and health science 2 (4), 177-185, 2020 | 56 | 2020 |
Cancer cachexia in a mouse model of oxidative stress JL Brown, MM Lawrence, B Ahn, P Kneis, KM Piekarz, R Qaisar, R Ranjit, ... Journal of Cachexia, Sarcopenia and Muscle 11 (6), 1688-1704, 2020 | 49 | 2020 |
Transcriptomic analysis of the development of skeletal muscle atrophy in cancer-cachexia in tumor-bearing mice TA Blackwell, I Cervenka, B Khatri, JL Brown, ME Rosa-Caldwell, DE Lee, ... Physiological genomics 50 (12), 1071-1082, 2018 | 48 | 2018 |
Neuron‐specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice S Bhaskaran, N Pollock, P C Macpherson, B Ahn, KM Piekarz, ... Aging Cell 19 (10), e13225, 2020 | 46 | 2020 |
Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy ME Rosa‐Caldwell, S Lim, WA Haynie, JL Brown, JW Deaver, ... Journal of cachexia, sarcopenia and muscle 12 (3), 717-730, 2021 | 44 | 2021 |
Hepatic alterations during the development and progression of cancer cachexia ME Rosa-Caldwell, JL Brown, DE Lee, MP Wiggs, RA Perry Jr, ... Applied Physiology, Nutrition, and Metabolism 45 (5), 500-512, 2020 | 40 | 2020 |
Targeting cPLA2 derived lipid hydroperoxides as a potential intervention for sarcopenia G Pharaoh, JL Brown, K Sataranatarajan, P Kneis, J Bian, R Ranjit, ... Scientific reports 10 (1), 13968, 2020 | 31 | 2020 |
Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia K Sataranatarajan, G Pharaoh, JL Brown, R Ranjit, KM Piekarz, K Street, ... Geroscience 42, 1101-1118, 2020 | 29 | 2020 |
PGC‐1α4 gene expression is suppressed by the IL‐6—MEK—ERK 1/2 MAPK signalling axis and altered by resistance exercise, obesity and muscle injury JL Brown, ME Rosa‐Caldwell, DE Lee, LA Brown, RA Perry, KL Shimkus, ... Acta Physiologica 220 (2), 275-288, 2017 | 29 | 2017 |
Translational machinery of mitochondrial mRNA is promoted by physical activity in Western diet‐induced obese mice DE Lee, JL Brown, ME Rosa, LA Brown, RA Perry, TA Washington, ... Acta Physiologica 218 (3), 167-177, 2016 | 27 | 2016 |
Differential effects of leucine supplementation in young and aged mice at the onset of skeletal muscle regeneration RA Perry Jr, LA Brown, DE Lee, JL Brown, JI Baum, NP Greene, ... Mechanisms of ageing and development 157, 7-16, 2016 | 26 | 2016 |
Cancer‐induced cardiac atrophy adversely affects myocardial redox state and mitochondrial oxidative characteristics DE Lee, JL Brown, ME Rosa‐Caldwell, RA Perry, LA Brown, WS Haynie, ... JCSM rapid communications 4 (1), 3-15, 2021 | 20 | 2021 |
Regulation of mitochondrial quality following repeated bouts of hindlimb unloading ME Rosa-Caldwell, JL Brown, RA Perry Jr, KL Shimkus, Y Shirazi-Fard, ... Applied Physiology, Nutrition, and Metabolism 45 (3), 264-274, 2020 | 20 | 2020 |