| Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin DL Farrens, C Altenbach, K Yang, WL Hubbell, HG Khorana science 274 (5288), 768-770, 1996 | 1550 | 1996 |
| Functionally different agonists induce distinct conformations in the G protein coupling domain of the β2Adrenergic receptor P Ghanouni, Z Gryczynski, JJ Steenhuis, TW Lee, DL Farrens, ... Journal of Biological Chemistry 276 (27), 24433-24436, 2001 | 482 | 2001 |
| Agonist-induced conformational changes in the G-protein-coupling domain of the β2 adrenergic receptor P Ghanouni, JJ Steenhuis, DL Farrens, BK Kobilka Proceedings of the National Academy of Sciences 98 (11), 5997-6002, 2001 | 440 | 2001 |
| Coupling ligand structure to specific conformational switches in the β2-adrenoceptor X Yao, C Parnot, X Deupi, VRP Ratnala, G Swaminath, D Farrens, ... Nature chemical biology 2 (8), 417-422, 2006 | 432 | 2006 |
| Structure of a signaling cannabinoid receptor 1-G protein complex KK Kumar, M Shalev-Benami, MJ Robertson, H Hu, SD Banister, ... Cell 176 (3), 448-458. e12, 2019 | 415 | 2019 |
| Biosensor reveals multiple sources for mitochondrial NAD+ XA Cambronne, ML Stewart, DH Kim, AM Jones-Brunette, RK Morgan, ... Science 352 (6292), 1474-1477, 2016 | 390 | 2016 |
| Structural features and light-dependent changes in the cytoplasmic interhelical E− F loop region of rhodopsin: a site-directed spin-labeling study C Altenbach, K Yang, DL Farrens, ZT Farahbakhsh, HG Khorana, ... Biochemistry 35 (38), 12470-12478, 1996 | 385 | 1996 |
| Domains responsible for constitutive and Ca2+-dependent interactions between calmodulin and small conductance Ca2+-activated potassium channels JE Keen, R Khawaled, DL Farrens, T Neelands, A Rivard, CT Bond, ... Journal of Neuroscience 19 (20), 8830-8838, 1999 | 293 | 1999 |
| Structure and Function in Rhodopsin: MEASUREMENT OF THE RATE OF METARHODOPSIN II DECAY BY FLUORESCENCE SPECTROSCOPY (∗) DL Farrens, HG Khorana Journal of Biological Chemistry 270 (10), 5073-5076, 1995 | 233 | 1995 |
| Conformational changes in rhodopsin: movement of helix F detected by site-specific chemical labeling and fluorescence spectroscopy TD Dunham, DL Farrens Journal of Biological Chemistry 274 (3), 1683-1690, 1999 | 215 | 1999 |
| Rhodopsin activation exposes a key hydrophobic binding site for the transducin α-subunit C terminus JM Janz, DL Farrens Journal of Biological Chemistry 279 (28), 29767-29773, 2004 | 140 | 2004 |
| Mapping proximity within proteins using fluorescence spectroscopy. A study of T4 lysozyme showing that tryptophan residues quench bimane fluorescence SE Mansoor, HS Mchaourab, DL Farrens Biochemistry 41 (8), 2475-2484, 2002 | 129 | 2002 |
| Structure and function in rhodopsin. Single cysteine substitution mutants in the cytoplasmic interhelical E− F loop region show position-specific effects in transducin activation K Yang, DL Farrens, WL Hubbell, HG Khorana Biochemistry 35 (38), 12464-12469, 1996 | 127 | 1996 |
| Structure and function in rhodopsin. Cysteines 65 and 316 are in proximity in a rhodopsin mutant as indicated by disulfide formation and interactions between attached spin labels K Yang, DL Farrens, C Altenbach, ZT Farahbakhsh, WL Hubbell, ... Biochemistry 35 (45), 14040-14046, 1996 | 123 | 1996 |
| Rhodopsin self-associates in asolectin liposomes SE Mansoor, K Palczewski, DL Farrens Proceedings of the National Academy of Sciences 103 (9), 3060-3065, 2006 | 118 | 2006 |
| Monomeric rhodopsin is the minimal functional unit required for arrestin binding H Tsukamoto, A Sinha, M DeWitt, DL Farrens Journal of molecular biology 399 (3), 501-511, 2010 | 115 | 2010 |
| Distance mapping in proteins using fluorescence spectroscopy: the tryptophan-induced quenching (TrIQ) method SE Mansoor, MA DeWitt, DL Farrens Biochemistry 49 (45), 9722-9731, 2010 | 108 | 2010 |
| Stability of dark state rhodopsin is mediated by a conserved ion pair in intradiscal loop E-2 JM Janz, JF Fay, DL Farrens Journal of Biological Chemistry 278 (19), 16982-16991, 2003 | 106 | 2003 |
| Fluorescence spectroscopy of rhodopsins: Insights and approaches U Alexiev, DL Farrens Biochimica et Biophysica Acta (BBA)-Bioenergetics 1837 (5), 694-709, 2014 | 101 | 2014 |
| Consensus and variant cAMP-regulated enhancers have distinct CREB-binding properties JC Craig, MA Schumacher, SE Mansoor, DL Farrens, RG Brennan, ... Journal of Biological Chemistry 276 (15), 11719-11728, 2001 | 98 | 2001 |
