Early-onset colorectal cancer: initial clues and current views LJ Hofseth, JR Hebert, A Chanda, H Chen, BL Love, MM Pena, ... Nature reviews Gastroenterology & hepatology 17 (6), 352-364, 2020 | 378 | 2020 |
A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol M Sajish, P Schimmel Nature 519 (7543), 370-373, 2015 | 171 | 2015 |
Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling M Sajish, Q Zhou, S Kishi, DM Valdez Jr, M Kapoor, M Guo, S Lee, S Kim, ... Nature chemical biology 8 (6), 547-554, 2012 | 103 | 2012 |
A charge reversal differentiates (p) ppGpp synthesis by monofunctional and bifunctional Rel proteins M Sajish, D Tiwari, D Rananaware, VK Nandicoori, B Prakash Journal of Biological Chemistry 282 (48), 34977-34983, 2007 | 61 | 2007 |
The significance of EXDD and RXKD motif conservation in Rel proteins M Sajish, S Kalayil, SK Verma, VK Nandicoori, B Prakash Journal of Biological Chemistry 284 (14), 9115-9123, 2009 | 59 | 2009 |
Nicotinamide augments the anti-inflammatory properties of resveratrol through PARP1 activation M Yanez, M Jhanji, K Murphy, RM Gower, M Sajish, E Jabbarzadeh Scientific reports 9 (1), 10219, 2019 | 56 | 2019 |
E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides N Jain, N Dhimole, AR Khan, D De, SK Tomar, M Sajish, D Dutta, ... Biochemical and biophysical research communications 379 (2), 201-205, 2009 | 56 | 2009 |
Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy D Blocquel, S Li, N Wei, H Daub, M Sajish, ML Erfurth, G Kooi, J Zhou, ... Nucleic acids research 45 (13), 8091-8104, 2017 | 47 | 2017 |
Dopamine triggers CTCF-dependent morphological and genomic remodeling of astrocytes A Galloway, A Adeluyi, B O'Donovan, ML Fisher, CN Rao, P Critchfield, ... Journal of Neuroscience 38 (21), 4846-4858, 2018 | 38 | 2018 |
Towards resolving the enigma of the dichotomy of resveratrol: cis-and trans-resveratrol have opposite effects on TyrRS-regulated PARP1 activation M Jhanji, CN Rao, M Sajish GeroScience, 1171–1200, 2021 | 26 | 2021 |
Cis- and trans-resveratrol have opposite effects on histone serine-ADP-ribosylation and tyrosine induced neurodegeneration M Jhanji, CN Rao, JC Massey, MC Hope III, X Zhou, CD Keene, T Ma, ... Nature Communications 13 (1), 3244, 2022 | 19 | 2022 |
Resveratrol protects against skin inflammation through inhibition of mast cell, sphingosine Kinase-1, Stat3 and NF-κB p65 signaling activation in mice CD Carlucci, Y Hui, AP Chumanevich, PA Robida, JW Fuseler, M Sajish, ... International Journal of Molecular Sciences 24 (7), 6707, 2023 | 15 | 2023 |
Acute and short-term administrations of delta-9-tetrahydrocannabinol modulate major gut metabolomic regulatory pathways in C57BL/6 mice M Oza, W Becker, PM Gummadidala, T Dias, MH Omebeyinje, L Chen, ... Scientific Reports 9 (1), 10520, 2019 | 7 | 2019 |
Toxic PARP trapping upon cAMP-induced DNA damage reinstates the efficacy of endocrine therapy and CDK4/6 inhibitors in treatment-refractory ER+ breast cancer O Saatci, M Cetin, M Uner, UM Tokat, I Chatzistamou, PG Ersan, ... Nature Communications 14 (1), 6997, 2023 | 4 | 2023 |
Tau regulates Arc stability in neuronal dendrites via a proteasome-sensitive but ubiquitin-independent pathway DW Yakout, A Shroff, W Wei, V Thaker, ZD Allen, M Sajish, TY Nazarko, ... Journal of Biological Chemistry 300 (5), 2024 | 1 | 2024 |
Targeting PDE4D reinstates toxic PARP trapping via cAMP-ROS-DNA damage axis and restores the efficacy of standard of care in treatment-refractory ER+ breast cancer O Saatci, M Cetin, M Uner, UM Tokat, I Chatzistamou, E Montaudon, ... Cancer Research 84 (6_Supplement), 563-563, 2024 | | 2024 |
Abstract A008: Toxic PARP trapping upon cAMP-induced DNA damage reinstates the efficacy of endocrine therapy and CDK4/6 inhibitors in treatment-refractory ER+ breast cancer O Saatci, M Cetin, M Uner, UM Tokat, I Chatzistamou, PG Ersan, ... Cancer Research 84 (1_Supplement), A008-A008, 2024 | | 2024 |
Tyrosine Inhibits TyrRS-mediated DNA Repair and Induces Neuronal Oxidative DNA Damage M Jhanji, C Nageswara Rao, X Zhou, D C Keene, T Ma, J Stewart, ... https://www.researchsquare.com/article/rs-785404/v1, 2021 | | 2021 |
Compositions and Methods Comprising Tyrosyl-tRNA Synthetases and Resveratrol Compounds P Schimmel, S Mathew US Patent WO/2016/069,716, 2016 | | 2016 |
E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides B Prakash, M Sajish, N Jain, SK Tomar, P Parrack, D Dutta, D De, ... ACADEMIC PRESS INC ELSEVIER SCIENCE, 2009 | | 2009 |