Extreme disorder in an ultrahigh-affinity protein complex A Borgia, MB Borgia, K Bugge, VM Kissling, PO Heidarsson, ... Nature 555 (7694), 61-66, 2018 | 668 | 2018 |
Binding without folding–the biomolecular function of disordered polyelectrolyte complexes B Schuler, A Borgia, MB Borgia, PO Heidarsson, ED Holmstrom, D Nettels, ... Current opinion in structural biology 60, 66-76, 2020 | 90 | 2020 |
Polyelectrolyte interactions enable rapid association and dissociation in high-affinity disordered protein complexes A Sottini, A Borgia, MB Borgia, K Bugge, D Nettels, A Chowdhury, ... Nature communications 11 (1), 5736, 2020 | 85 | 2020 |
Direct single-molecule observation of calcium-dependent misfolding in human neuronal calcium sensor-1 PO Heidarsson, MM Naqvi, MR Otazo, A Mossa, BB Kragelund, ... Proceedings of the National Academy of Sciences 111 (36), 13069-13074, 2014 | 65 | 2014 |
Release of linker histone from the nucleosome driven by polyelectrolyte competition with a disordered protein PO Heidarsson, D Mercadante, A Sottini, D Nettels, MB Borgia, A Borgia, ... Nature Chemistry 14 (2), 224-231, 2022 | 51 | 2022 |
Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands S Erlendsson, M Rathje, PO Heidarsson, FM Poulsen, KL Madsen, ... Journal of Biological Chemistry 289 (36), 25327-25340, 2014 | 48 | 2014 |
The C-terminal Tail of Human Neuronal Calcium Sensor 1 Regulates the Conformational Stability of the Ca< sup> 2+</sup>-Activated State PO Heidarsson, IJ Bjerrum-Bohr, GA Jensen, O Pongs, BE Finn, ... Journal of Molecular Biology 417 (1-2), 51-64, 2012 | 48 | 2012 |
Multifunctional Intrinsically Disordered Regions in Transcription Factors M Már, K Nitsenko, PO Heidarsson Chemistry–A European Journal, 2023 | 38 | 2023 |
A Highly Compliant Protein Native State with a Spontaneous-like Mechanical Unfolding Pathway PO Heidarsson, I Valpapuram, C Camilloni, A Imparato, G Tiana, ... Journal of the American Chemical Society 134 (41), 17068-17075, 2012 | 37 | 2012 |
Single-molecule folding mechanism of an EF-hand neuronal calcium sensor PO Heidarsson, MR Otazo, L Bellucci, A Mossa, A Imparato, E Paci, ... Structure 21 (10), 1812-1821, 2013 | 33 | 2013 |
PED in 2024: improving the community deposition of structural ensembles for intrinsically disordered proteins H Ghafouri, T Lazar, A Del Conte, LG Tenorio Ku, P Tompa, SCE Tosatto, ... Nucleic acids research 52 (D1), D536-D544, 2024 | 32 | 2024 |
Exploring the minimally frustrated energy landscape of unfolded ACBP V Ozenne, JK Noel, PO Heidarsson, S Brander, FM Poulsen, MR Jensen, ... Journal of Molecular Biology 426 (3), 722-734, 2014 | 25 | 2014 |
Single-molecule folding mechanisms of the apo-and Mg2+-bound states of human neuronal calcium sensor-1 MM Naqvi, PO Heidarsson, MR Otazo, A Mossa, BB Kragelund, ... Biophysical journal 109 (1), 113-123, 2015 | 21 | 2015 |
Effects of ligand binding on the energy landscape of Acyl-CoA-binding protein P Sonar, L Bellucci, A Mossa, PO Heidarsson, BB Kragelund, C Cecconi Biophysical Journal 119 (9), 1821-1832, 2020 | 20 | 2020 |
Structural features and dynamics of a cold‐adapted alkaline phosphatase studied by EPR spectroscopy PO Heidarsson, ST Sigurdsson, B Asgeirsson The FEBS Journal 276 (10), 2725-2735, 2009 | 19 | 2009 |
DNA binding redistributes activation domain ensemble and accessibility in pioneer factor Sox2 S Bjarnason, J McIvor, A Prestel, K Demeny, J Bullerjahn, BB Kragelund, ... Nature Communications 123 (3), 73a, 2024 | 14 | 2024 |
Solution properties of the archaeal CRISPR DNA repeat-binding homeodomain protein Cbp2 CS Kenchappa, PO Heidarsson, BB Kragelund, RA Garrett, FM Poulsen Nucleic acids research 41 (5), 3424-3435, 2013 | 14 | 2013 |
Disordered proteins enable histone chaperoning on the nucleosome PO Heidarsson, D Mercadante, A Sottini, D Nettels, MB Borgia, A Borgia, ... BioRxiv, 2020.04. 17.046243, 2020 | 13 | 2020 |
From folding to function: complex macromolecular reactions unraveled one-by-one with optical tweezers PO Heidarsson, C Cecconi Essays in Biochemistry 65 (1), 129-142, 2021 | 9 | 2021 |
The complex conformational dynamics of neuronal calcium sensor-1: a single molecule perspective D Choudhary, BB Kragelund, PO Heidarsson, C Cecconi Frontiers in molecular neuroscience 11, 468, 2018 | 9 | 2018 |