| Experimental comparison and cross-validation of the Affymetrix and Illumina gene expression analysis platforms M Barnes, J Freudenberg, S Thompson, B Aronow, P Pavlidis Nucleic acids research 33 (18), 5914-5923, 2005 | 318 | 2005 |
| Histone-fold domain protein NF-Y promotes chromatin accessibility for cell type-specific master transcription factors AJ Oldfield, P Yang, AE Conway, S Cinghu, JM Freudenberg, ... Molecular cell 55 (5), 708-722, 2014 | 199 | 2014 |
| Fip1 regulates mRNA alternative polyadenylation to promote stem cell self‐renewal B Lackford, C Yao, GM Charles, L Weng, X Zheng, EA Choi, X Xie, J Wan, ... The EMBO journal 33 (8), 878-889, 2014 | 189 | 2014 |
| Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells D Menendez, TA Nguyen, JM Freudenberg, VJ Mathew, CW Anderson, ... Nucleic acids research 41 (15), 7286-7301, 2013 | 187 | 2013 |
| Human and mouse skeletal muscle stem cells: convergent and divergent mechanisms of myogenesis A Bareja, JA Holt, G Luo, C Chang, J Lin, AC Hinken, JM Freudenberg, ... PloS one 9 (2), e90398, 2014 | 115 | 2014 |
| Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity JM Freudenberg, S Ghosh, BL Lackford, S Yellaboina, X Zheng, R Li, ... Nucleic acids research 40 (8), 3364-3377, 2012 | 108 | 2012 |
| Retinoic acid-related orphan receptor γ (RORγ): a novel participant in the diurnal regulation of hepatic gluconeogenesis and insulin sensitivity Y Takeda, HS Kang, J Freudenberg, LM DeGraff, R Jothi, AM Jetten PLoS genetics 10 (5), e1004331, 2014 | 98 | 2014 |
| Ldb1-nucleated transcription complexes function as primary mediators of global erythroid gene activation LQ Li, J Freudenberg, K Cui, R Dale, SH Song, A Dean, K Zhao, R Jothi, ... Blood, The Journal of the American Society of Hematology 121 (22), 4575-4585, 2013 | 97 | 2013 |
| Effect of Roux-en-Y gastric bypass surgery on bile acid metabolism in normal and obese diabetic rats HY Bhutta, N Rajpal, W White, JM Freudenberg, Y Liu, J Way, D Rajpal, ... PloS one 10 (3), e0122273, 2015 | 90 | 2015 |
| Clean: Clustering enrichment analysis JM Freudenberg, VK Joshi, Z Hu, M Medvedovic BMC bioinformatics 10, 1-15, 2009 | 87 | 2009 |
| Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiation X Zheng, R Dumitru, BL Lackford, JM Freudenberg, AP Singh, TK Archer, ... Stem cells 30 (5), 910-922, 2012 | 86 | 2012 |
| The epigenetic signature of systemic insulin resistance in obese women P Arner, AS Sahlqvist, I Sinha, H Xu, X Yao, D Waterworth, D Rajpal, ... Diabetologia 59, 2393-2405, 2016 | 76 | 2016 |
| Network-based identification and prioritization of key regulators of coronary artery disease loci Y Zhao, J Chen, JM Freudenberg, Q Meng, CARDIoGRAM Consortium, ... Arteriosclerosis, thrombosis, and vascular biology 36 (5), 928-941, 2016 | 68 | 2016 |
| Evaluation of analytical methods for connectivity map data J Cheng, Q Xie, V Kumar, M Hurle, JM Freudenberg, L Yang, P Agarwal Biocomputing 2013, 5-16, 2013 | 64 | 2013 |
| Assessment of rosacea symptom severity by genome-wide association study and expression analysis highlights immuno-inflammatory and skin pigmentation genes JL Aponte, MN Chiano, LM Yerges-Armstrong, DA Hinds, C Tian, A Gupta, ... Human Molecular Genetics 27 (15), 2762-2772, 2018 | 47 | 2018 |
| Expression profiling of human donor lungs to understand primary graft dysfunction after lung transplantation M Ray, S Dharmarajan, J Freudenberg, W Zhang, GA Patterson American Journal of Transplantation 7 (10), 2396-2405, 2007 | 47 | 2007 |
| A semi-parametric Bayesian model for unsupervised differential co-expression analysis JM Freudenberg, S Sivaganesan, M Wagner, M Medvedovic BMC bioinformatics 11, 1-15, 2010 | 46 | 2010 |
| Pharmacological SIRT1 activation improves mortality and markedly alters transcriptional profiles that accompany experimental sepsis SM Opal, JL Ellis, V Suri, JM Freudenberg, GP Vlasuk, Y Li, AB Chahin, ... Shock 45 (4), 411-418, 2016 | 44 | 2016 |
| Assessing colonic exposure, safety, and clinical activity of SRT2104, a novel oral SIRT1 activator, in patients with mild to moderate ulcerative colitis BE Sands, S Joshi, J Haddad, JM Freudenberg, DE Oommen, ... Inflammatory bowel diseases 22 (3), 607-614, 2016 | 43 | 2016 |
| A phase I randomized controlled trial to evaluate safety and clinical effect of topically applied GSK2981278 ointment in a psoriasis plaque test EG Kang, S Wu, A Gupta, YL von Mackensen, H Siemetzki, ... British Journal of Dermatology 178 (6), 1427-1429, 2018 | 36 | 2018 |
