| Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle DW Frederick, E Loro, L Liu, A Davila, K Chellappa, IM Silverman, ... Cell metabolism 24 (2), 269-282, 2016 | 379 | 2016 |
| Clinicogenomic Analysis of FGFR2-Rearranged Cholangiocarcinoma Identifies Correlates of Response and Mechanisms of Resistance to Pemigatinib IM Silverman, A Hollebecque, L Friboulet, S Owens, RC Newton, H Zhen, ... Cancer discovery 11 (2), 326-339, 2021 | 222 | 2021 |
| FIGHT-101, a first-in-human study of potent and selective FGFR 1-3 inhibitor pemigatinib in pan-cancer patients with FGF/FGFR alterations and advanced malignancies V Subbiah, NO Iannotti, M Gutierrez, DC Smith, L Féliz, CF Lihou, C Tian, ... Annals of Oncology 33 (5), 522-533, 2022 | 158 | 2022 |
| HAMR: high-throughput annotation of modified ribonucleotides P Ryvkin, YY Leung, IM Silverman, M Childress, O Valladares, I Dragomir, ... Rna 19 (12), 1684-1692, 2013 | 148 | 2013 |
| Global analysis of the RNA-protein interaction and RNA secondary structure landscapes of the Arabidopsis nucleus SJ Gosai, SW Foley, D Wang, IM Silverman, N Selamoglu, ADL Nelson, ... Molecular cell 57 (2), 376-388, 2015 | 122 | 2015 |
| Intratumoral heterogeneity and TERT promoter mutations in progressive/higher-grade meningiomas TA Juratli, C Thiede, MVA Koerner, SS Tummala, D Daubner, ... Oncotarget 8 (65), 109228, 2017 | 113 | 2017 |
| RNase-mediated protein footprint sequencing reveals protein-binding sites throughout the human transcriptome IM Silverman, F Li, A Alexander, L Goff, C Trapnell, JL Rinn, BD Gregory Genome biology 15, 1-16, 2014 | 98 | 2014 |
| Evaluating the impact of sequencing depth on transcriptome profiling in human adipose Y Liu, JF Ferguson, C Xue, IM Silverman, B Gregory, MP Reilly, M Li PLoS One 8 (6), e66883, 2013 | 90 | 2013 |
| DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome TA Juratli, D McCabe, N Nayyar, EA Williams, IM Silverman, SS Tummala, ... Acta neuropathologica 136, 779-792, 2018 | 85 | 2018 |
| The poly (C) binding protein Pcbp2 and its retrotransposed derivative Pcbp1 are independently essential to mouse development LR Ghanem, A Kromer, IM Silverman, P Chatterji, E Traxler, ... Molecular and cellular biology, 2016 | 81 | 2016 |
| Tissue-specific RNA-Seq in human evoked inflammation identifies blood and adipose LincRNA signatures of cardiometabolic diseases Y Liu, JF Ferguson, C Xue, RL Ballantyne, IM Silverman, SJ Gosai, ... Arteriosclerosis, thrombosis, and vascular biology 34 (4), 902-912, 2014 | 79 | 2014 |
| Cytoplasmic poly (A) binding protein-1 binds to genomically encoded sequences within mammalian mRNAs HK Kini, IM Silverman, X Ji, BD Gregory, SA Liebhaber rna 22, 61-74, 2015 | 68 | 2015 |
| Truncated FGFR2 is a clinically actionable oncogene in multiple cancers D Zingg, J Bhin, J Yemelyanenko, SM Kas, F Rolfs, C Lutz, JK Lee, ... Nature 608 (7923), 609-617, 2022 | 67 | 2022 |
| Genomic era analyses of RNA secondary structure and RNA-binding proteins reveal their significance to post-transcriptional regulation in plants IM Silverman, F Li, BD Gregory Plant Science 205, 55-62, 2013 | 59 | 2013 |
| Impact of poly(A)-tail G-content on Arabidopsis PAB binding and their role in enhancing translational efficiency T Zhao, Q Huan, J Sun, C Liu, X Hou, X Yu, IM Silverman, Y Zhang, ... Genome biology 20, 1-12, 2019 | 58 | 2019 |
| Antitumor Activity of Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor, in ETV6-NTRK3–Positive Acute Myeloid Leukemia KM Smith, PC Fagan, E Pomari, G Germano, C Frasson, C Walsh, ... Molecular Cancer Therapeutics 17 (2), 455-463, 2018 | 50 | 2018 |
| Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial results TA Yap, E Fontana, EK Lee, DR Spigel, M Højgaard, S Lheureux, ... Nature medicine 29 (6), 1400-1411, 2023 | 48 | 2023 |
| Chemical modifications mark alternatively spliced and uncapped messenger RNAs in Arabidopsis LE Vandivier, R Campos, PP Kuksa, IM Silverman, LS Wang, BD Gregory The Plant Cell 27 (11), 3024-3037, 2015 | 47 | 2015 |
| Comprehensive genomic profiling in FIGHT-202 reveals the landscape of actionable alterations in advanced cholangiocarcinoma. IM Silverman, K Murugesan, CF Lihou, L Féliz, GM Frampton, RC Newton, ... Journal of Clinical Oncology 37 (15_suppl), 4080-4080, 2019 | 43 | 2019 |
| Terpene metabolic engineering via nuclear or chloroplast genomes profoundly and globally impacts off‐target pathways through metabolite signalling EK Pasoreck, J Su, IM Silverman, SJ Gosai, BD Gregory, JS Yuan, ... Plant biotechnology journal 14 (9), 1862-1875, 2016 | 40 | 2016 |
Brian D. GregoryProfessor of Biology, University of PennsylavaniaEmail yang diverifikasi di sas.upenn.edu