| MicroRNA expression profiles classify human cancers J Lu, G Getz, EA Miska, E Alvarez-Saavedra, J Lamb, D Peck, ... nature 435 (7043), 834-838, 2005 | 12073 | 2005 |
| Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals M Guttman, I Amit, M Garber, C French, MF Lin, D Feldser, M Huarte, ... Nature 458 (7235), 223-227, 2009 | 4916 | 2009 |
| A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia MB Kastan, Q Zhan, WS El-Deiry, F Carrier, T Jacks, WV Walsh, ... Cell 71 (4), 587-597, 1992 | 4157 | 1992 |
| p53-dependent apoptosis modulates the cytotoxicity of anticancer agents SW Lowe, HE Ruley, T Jacks, DE Housman Cell 74 (6), 957-967, 1993 | 3998 | 1993 |
| p53 is required for radiation-induced apoptosis in mouse thymocytes SW Lowe, EM Schmitt, SW Smith, BA Osborne, T Jacks Nature 362 (6423), 847-849, 1993 | 3873 | 1993 |
| Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 DA Barbie, P Tamayo, JS Boehm, SY Kim, SE Moody, IF Dunn, ... Nature 462 (7269), 108-112, 2009 | 3430 | 2009 |
| Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours TG Graeber, C Osmanian, T Jacks, DE Housman, CJ Koch, SW Lowe, ... nature 379 (6560), 88-91, 1996 | 3146 | 1996 |
| Identification of bronchioalveolar stem cells in normal lung and lung cancer CFB Kim, EL Jackson, AE Woolfenden, S Lawrence, I Babar, S Vogel, ... Cell 121 (6), 823-835, 2005 | 2933 | 2005 |
| Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse SR Hingorani, EF Petricoin, A Maitra, V Rajapakse, C King, MA Jacobetz, ... Cancer cell 4 (6), 437-450, 2003 | 2912 | 2003 |
| Tumor spectrum analysis in p53-mutant mice T Jacks, L Remington, BO Williams, EM Schmitt, S Halachmi, RT Bronson, ... Current biology 4 (1), 1-7, 1994 | 2494 | 1994 |
| A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response M Huarte, M Guttman, D Feldser, M Garber, MJ Koziol, ... Cell 142 (3), 409-419, 2010 | 2458 | 2010 |
| Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras EL Jackson, N Willis, K Mercer, RT Bronson, D Crowley, R Montoya, ... Genes & development 15 (24), 3243-3248, 2001 | 2263 | 2001 |
| Effects of an Rb mutation in the mouse T Jacks, A Fazeli, EM Schmitt, RT Bronson, MA Goodell, RA Weinberg Nature 359 (6393), 295-300, 1992 | 2254 | 1992 |
| Restoration of p53 function leads to tumour regression in vivo A Ventura, DG Kirsch, ME McLaughlin, DA Tuveson, J Grimm, L Lintault, ... Nature 445 (7128), 661-665, 2007 | 2206 | 2007 |
| Targeted deletion reveals essential and overlapping functions of the miR-17∼ 92 family of miRNA clusters A Ventura, AG Young, MM Winslow, L Lintault, A Meissner, SJ Erkeland, ... Cell 132 (5), 875-886, 2008 | 2055 | 2008 |
| p53 status and the efficacy of cancer therapy in vivo SW Lowe, S Bodis, A McClatchey, L Remington, HE Ruley, DE Fisher, ... Science 266 (5186), 807-810, 1994 | 2041 | 1994 |
| Sunburn and p53 in the onset of skin cancer A Ziegler, AS Jonason, DJ Leffellt, JA Simon, HW Sharma, J Kimmelman, ... Nature 372 (6508), 773-776, 1994 | 1873 | 1994 |
| Impaired microRNA processing enhances cellular transformation and tumorigenesis MS Kumar, J Lu, KL Mercer, TR Golub, T Jacks Nature genetics 39 (5), 673-677, 2007 | 1831 | 2007 |
| Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53 LR Livingstone, A White, J Sprouse, E Livanos, T Jacks, TD Tlsty Cell 70 (6), 923-935, 1992 | 1729 | 1992 |
| Radiation-induced cell cycle arrest compromised by p21 deficiency J Brugarolas, C Chandrasekaran, JI Gordon, D Beach, T Jacks, ... Nature 377 (6549), 552-557, 1995 | 1691 | 1995 |
