Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes Y Tanaka, G Suzuki, T Matsuwaki, M Hosokawa, G Serrano, TG Beach, ... Human molecular genetics 26 (5), 969-988, 2017 | 181 | 2017 |
Bovine C-terminal octapeptide of RFamide-related peptide-3 suppresses luteinizing hormone (LH) secretion from the pituitary as well as pulsatile LH secretion in bovines H Kadokawa, M Shibata, Y Tanaka, T Kojima, K Matsumoto, K Oshima, ... Domestic animal endocrinology 36 (4), 219-224, 2009 | 175 | 2009 |
Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice Y Tanaka, JK Chambers, T Matsuwaki, K Yamanouchi, M Nishihara Acta neuropathologica communications 2, 1-15, 2014 | 158 | 2014 |
Increased lysosomal biogenesis in activated microglia and exacerbated neuronal damage after traumatic brain injury in progranulin-deficient mice Y Tanaka, T Matsuwaki, K Yamanouchi, M Nishihara Neuroscience 250, 8-19, 2013 | 149 | 2013 |
Phosphorylation of TAR DNA-binding protein of 43 kDa (TDP-43) by truncated casein kinase 1δ triggers mislocalization and accumulation of TDP-43 T Nonaka, G Suzuki, Y Tanaka, F Kametani, S Hirai, H Okado, T Miyashita, ... Journal of Biological Chemistry 291 (11), 5473-5483, 2016 | 140 | 2016 |
Exacerbated inflammatory responses related to activated microglia after traumatic brain injury in progranulin-deficient mice Y Tanaka, T Matsuwaki, K Yamanouchi, M Nishihara Neuroscience 231, 49-60, 2013 | 131 | 2013 |
Multiple therapeutic effects of progranulin on experimental acute ischaemic stroke M Kanazawa, K Kawamura, T Takahashi, M Miura, Y Tanaka, M Koyama, ... Brain 138 (7), 1932-1948, 2015 | 126 | 2015 |
Gain-of-function profilin 1 mutations linked to familial amyotrophic lateral sclerosis cause seed-dependent intracellular TDP-43 aggregation Y Tanaka, T Nonaka, G Suzuki, F Kametani, M Hasegawa Human molecular genetics 25 (7), 1420-1433, 2016 | 75 | 2016 |
Profilin 1 mutants form aggregates that induce accumulation of prion-like TDP-43 Y Tanaka, M Hasegawa Prion 10 (4), 283-289, 2016 | 33 | 2016 |
Progranulin haploinsufficiency reduces amyloid beta deposition in Alzheimer’s disease model mice M Hosokawa, Y Tanaka, T Arai, H Kondo, H Akiyama, M Hasegawa Experimental animals 67 (1), 63-70, 2018 | 19 | 2018 |
Taurine counteracts the suppressive effect of lipopolysaccharide on neurogenesis in the hippocampus of rats G Wu, T Matsuwaki, Y Tanaka, K Yamanouchi, J Hu, M Nishihara Taurine 8: Volume 1: The Nervous System, Immune System, Diabetes and the …, 2013 | 16 | 2013 |
Kinase activity-tagged western blotting assay M Eto, S Katsuki, Y Tanaka, K Takeya BioTechniques 68 (4), 211-213, 2020 | 7 | 2020 |
Dysregulation of the progranulin-driven autophagy-lysosomal pathway mediates secretion of the nuclear protein TDP-43 Y Tanaka, S Ito, Y Honma, M Hasegawa, F Kametani, G Suzuki, ... Journal of Biological Chemistry 299 (11), 2023 | 5 | 2023 |
Overexpression of progranulin increases pathological protein accumulation by suppressing autophagic flux Y Tanaka, S Kusumoto, Y Honma, K Takeya, M Eto Biochemical and Biophysical Research Communications 611, 78-84, 2022 | 5 | 2022 |
Abemaciclib and Vacuolin-1 induce vacuole-like autolysosome formation–A new tool to study autophagosome-lysosome fusion Y Tanaka, H Hino, K Takeya, M Eto Biochemical and Biophysical Research Communications 614, 191-197, 2022 | 3 | 2022 |
Possible roles of N-and C-terminal unstructured tails of CPI-17 in regulating Ca2+ sensitization force of smooth muscle M Eto, S Katsuki, M Ohashi, Y Miyagawa, Y Tanaka, K Takeya, T Kitazawa Journal of Smooth Muscle Research 58, 22-33, 2022 | 3 | 2022 |
TDP-43 Secretion via Extracellular Vesicles Is Regulated by Macroautophagy Y Tanaka, S Ito, G Suzuki Autophagy Reports 3 (1), 2291250, 2024 | 2 | 2024 |
Evaluation of LC3-II Release via Extracellular Vesicles in Relation to the Accumulation of Intracellular LC3-positive Vesicles S Ito, Y Tanaka Journal of Visualized Experiments (JoVE), e67385, 2024 | 2 | 2024 |
Convulsive responses to seizure-inducible drugs are exacerbated in progranulin-deficient mice M Kuroda, T Matsuwaki, Y Tanaka, K Yamanouchi, M Nishihara NeuroReport 31 (6), 478-483, 2020 | 2 | 2020 |
Progranulin regulations of lysosomal homeostasis and its involvement in neurodegenerative diseases Y Tanaka Progranulin and Central Nervous System Disorders, 85-103, 2019 | 1 | 2019 |