Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq L Chen, JW Lee, CL Chou, AV Nair, MA Battistone, TG Păunescu, ... Proceedings of the National Academy of Sciences 114 (46), E9989-E9998, 2017 | 250 | 2017 |
A comprehensive map of mRNAs and their isoforms across all 14 renal tubule segments of mouse L Chen, CL Chou, MA Knepper Journal of the American Society of Nephrology 32 (4), 897-912, 2021 | 173 | 2021 |
Representation and relative abundance of cell-type selective markers in whole-kidney RNA-Seq data JZ Clark, L Chen, CL Chou, HJ Jung, JW Lee, MA Knepper Kidney international 95 (4), 787-796, 2019 | 128 | 2019 |
Renal-tubule epithelial cell nomenclature for single-cell RNA-sequencing studies L Chen, JZ Clark, JW Nelson, B Kaissling, DH Ellison, MA Knepper Journal of the American Society of Nephrology 30 (8), 1358-1364, 2019 | 101 | 2019 |
Targeted single-cell RNA-seq identifies minority cell types of kidney distal nephron L Chen, CL Chou, MA Knepper Journal of the American Society of Nephrology 32 (4), 886-896, 2021 | 94 | 2021 |
Aqp2-expressing cells give rise to renal intercalated cells H Wu, L Chen, Q Zhou, X Zhang, S Berger, J Bi, DE Lewis, Y Xia, ... Journal of the American Society of Nephrology 24 (2), 243-252, 2013 | 82 | 2013 |
Aqp5 is a new transcriptional target of Dot1a and a regulator of Aqp2 H Wu, L Chen, X Zhang, Q Zhou, JM Li, S Berger, Z Borok, B Zhou, Z Xiao, ... PloS one 8 (1), e53342, 2013 | 65 | 2013 |
Does SARS-CoV-2 infect the kidney? S Khan, L Chen, CR Yang, V Raghuram, SJ Khundmiri, MA Knepper Journal of the American Society of Nephrology 31 (12), 2746-2748, 2020 | 62 | 2020 |
Transcriptomes of major proximal tubule cell culture models SJ Khundmiri, L Chen, ED Lederer, CR Yang, MA Knepper Journal of the American Society of Nephrology 32 (1), 86-97, 2021 | 52 | 2021 |
Loss of histone H3 K79 methyltransferase Dot1l facilitates kidney fibrosis by upregulating endothelin 1 through histone deacetylase 2 L Zhang, L Chen, C Gao, E Chen, AR Lightle, L Foulke, B Zhao, ... Journal of the American Society of Nephrology 31 (2), 337-349, 2020 | 42 | 2020 |
Emerging role of the calcium-activated, small conductance, SK3 K+ channel in distal tubule function: regulation by TRPV4 J Berrout, M Mamenko, OL Zaika, L Chen, W Zang, O Pochynyuk, ... PloS one 9 (4), e95149, 2014 | 39 | 2014 |
“SLC-omics” of the kidney: solute transporters along the nephron S Lewis, L Chen, V Raghuram, SJ Khundmiri, CL Chou, CR Yang, ... American Journal of Physiology-Cell Physiology 321 (3), C507-C518, 2021 | 34 | 2021 |
RNA-Seq and protein mass spectrometry in microdissected kidney tubules reveal signaling processes initiating lithium-induced nephrogenic diabetes insipidus CC Sung, L Chen, K Limbutara, HJ Jung, GG Gilmer, CR Yang, SH Lin, ... Kidney international 96 (2), 363-377, 2019 | 33 | 2019 |
Af17 deficiency increases sodium excretion and decreases blood pressure L Chen, H Wu, M Pochynyuk, MR Reisenauer, Z Zhang, L Huang, ... Journal of the American Society of Nephrology 22 (6), 1076-1086, 2011 | 31 | 2011 |
An Af9 cis-element directly targets Dot1a to mediate transcriptional repression of the αENaC gene W Zhang, Z Yu, H Wu, L Chen, Q Kong, BC Kone American Journal of Physiology-Renal Physiology 304 (4), F367-F375, 2013 | 25 | 2013 |
Spironolactone rescues Dot1a-Af9-mediated repression of endothelin-1 and improves kidney injury in streptozotocin-induced diabetic rats Q Zhou, K Liu, H Wu, L Chen, V Pouranan, M Yuan, Z Xiao, W Peng, ... Public Library of Science 7 (10), e47360, 2012 | 24 | 2012 |
Dot1l deficiency leads to increased intercalated cells and upregulation of V-ATPase B1 in mice Z Xiao, L Chen, Q Zhou, W Zhang Experimental cell research 344 (2), 167-175, 2016 | 22 | 2016 |
Multiomics analyses reveal sex differences in mouse renal proximal subsegments L Chen, CL Chou, CR Yang, MA Knepper Journal of the American Society of Nephrology 34 (5), 829-845, 2023 | 21 | 2023 |
AF17 facilitates Dot1a nuclear export and upregulates ENaC-mediated Na+ transport in renal collecting duct cells H Wu, L Chen, Q Zhou, W Zhang PLoS One 6 (11), e27429, 2011 | 20 | 2011 |
Landscape of GPCR expression along the mouse nephron BG Poll, L Chen, CL Chou, V Raghuram, MA Knepper American Journal of Physiology-Renal Physiology 321 (1), F50-F68, 2021 | 17 | 2021 |