Ikuti
Lihe Chen
Lihe Chen
Staff Scientist at the National Institutes of Health (NIH)
Email yang diverifikasi di nih.gov
Judul
Dikutip oleh
Dikutip oleh
Tahun
Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq
L Chen, JW Lee, CL Chou, AV Nair, MA Battistone, TG Păunescu, ...
Proceedings of the National Academy of Sciences 114 (46), E9989-E9998, 2017
2502017
A comprehensive map of mRNAs and their isoforms across all 14 renal tubule segments of mouse
L Chen, CL Chou, MA Knepper
Journal of the American Society of Nephrology 32 (4), 897-912, 2021
1732021
Representation and relative abundance of cell-type selective markers in whole-kidney RNA-Seq data
JZ Clark, L Chen, CL Chou, HJ Jung, JW Lee, MA Knepper
Kidney international 95 (4), 787-796, 2019
1282019
Renal-tubule epithelial cell nomenclature for single-cell RNA-sequencing studies
L Chen, JZ Clark, JW Nelson, B Kaissling, DH Ellison, MA Knepper
Journal of the American Society of Nephrology 30 (8), 1358-1364, 2019
1012019
Targeted single-cell RNA-seq identifies minority cell types of kidney distal nephron
L Chen, CL Chou, MA Knepper
Journal of the American Society of Nephrology 32 (4), 886-896, 2021
942021
Aqp2-expressing cells give rise to renal intercalated cells
H Wu, L Chen, Q Zhou, X Zhang, S Berger, J Bi, DE Lewis, Y Xia, ...
Journal of the American Society of Nephrology 24 (2), 243-252, 2013
822013
Aqp5 is a new transcriptional target of Dot1a and a regulator of Aqp2
H Wu, L Chen, X Zhang, Q Zhou, JM Li, S Berger, Z Borok, B Zhou, Z Xiao, ...
PloS one 8 (1), e53342, 2013
652013
Does SARS-CoV-2 infect the kidney?
S Khan, L Chen, CR Yang, V Raghuram, SJ Khundmiri, MA Knepper
Journal of the American Society of Nephrology 31 (12), 2746-2748, 2020
622020
Transcriptomes of major proximal tubule cell culture models
SJ Khundmiri, L Chen, ED Lederer, CR Yang, MA Knepper
Journal of the American Society of Nephrology 32 (1), 86-97, 2021
522021
Loss of histone H3 K79 methyltransferase Dot1l facilitates kidney fibrosis by upregulating endothelin 1 through histone deacetylase 2
L Zhang, L Chen, C Gao, E Chen, AR Lightle, L Foulke, B Zhao, ...
Journal of the American Society of Nephrology 31 (2), 337-349, 2020
422020
Emerging role of the calcium-activated, small conductance, SK3 K+ channel in distal tubule function: regulation by TRPV4
J Berrout, M Mamenko, OL Zaika, L Chen, W Zang, O Pochynyuk, ...
PloS one 9 (4), e95149, 2014
392014
“SLC-omics” of the kidney: solute transporters along the nephron
S Lewis, L Chen, V Raghuram, SJ Khundmiri, CL Chou, CR Yang, ...
American Journal of Physiology-Cell Physiology 321 (3), C507-C518, 2021
342021
RNA-Seq and protein mass spectrometry in microdissected kidney tubules reveal signaling processes initiating lithium-induced nephrogenic diabetes insipidus
CC Sung, L Chen, K Limbutara, HJ Jung, GG Gilmer, CR Yang, SH Lin, ...
Kidney international 96 (2), 363-377, 2019
332019
Af17 deficiency increases sodium excretion and decreases blood pressure
L Chen, H Wu, M Pochynyuk, MR Reisenauer, Z Zhang, L Huang, ...
Journal of the American Society of Nephrology 22 (6), 1076-1086, 2011
312011
An Af9 cis-element directly targets Dot1a to mediate transcriptional repression of the αENaC gene
W Zhang, Z Yu, H Wu, L Chen, Q Kong, BC Kone
American Journal of Physiology-Renal Physiology 304 (4), F367-F375, 2013
252013
Spironolactone rescues Dot1a-Af9-mediated repression of endothelin-1 and improves kidney injury in streptozotocin-induced diabetic rats
Q Zhou, K Liu, H Wu, L Chen, V Pouranan, M Yuan, Z Xiao, W Peng, ...
Public Library of Science 7 (10), e47360, 2012
242012
Dot1l deficiency leads to increased intercalated cells and upregulation of V-ATPase B1 in mice
Z Xiao, L Chen, Q Zhou, W Zhang
Experimental cell research 344 (2), 167-175, 2016
222016
Multiomics analyses reveal sex differences in mouse renal proximal subsegments
L Chen, CL Chou, CR Yang, MA Knepper
Journal of the American Society of Nephrology 34 (5), 829-845, 2023
212023
AF17 facilitates Dot1a nuclear export and upregulates ENaC-mediated Na+ transport in renal collecting duct cells
H Wu, L Chen, Q Zhou, W Zhang
PLoS One 6 (11), e27429, 2011
202011
Landscape of GPCR expression along the mouse nephron
BG Poll, L Chen, CL Chou, V Raghuram, MA Knepper
American Journal of Physiology-Renal Physiology 321 (1), F50-F68, 2021
172021
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