Adaptation of Pseudomonas aeruginosa in Cystic Fibrosis Airways Influences Virulence of Staphylococcus aureus In Vitro and Murine Models of Co-Infection R Baldan, C Cigana, F Testa, I Bianconi, M De Simone, D Pellin, ... PloS one 9 (3), e89614, 2014 | 204 | 2014 |
Pseudomonas aeruginosa exploits lipid A and muropeptides modification as a strategy to lower innate immunity during cystic fibrosis lung infection C Cigana, L Curcurù, MR Leone, T Ieranò, NI Lorè, I Bianconi, A Silipo, ... PloS one 4 (12), e8439, 2009 | 190 | 2009 |
Anti-inflammatory effects of azithromycin in cystic fibrosis airway epithelial cells C Cigana, E Nicolis, M Pasetto, BM Assael, P Melotti Biochemical and biophysical research communications 350 (4), 977-982, 2006 | 156 | 2006 |
Azithromycin selectively reduces tumor necrosis factor alpha levels in cystic fibrosis airway epithelial cells C Cigana, BM Assael, P Melotti Antimicrobial Agents and Chemotherapy 51 (3), 975-981, 2007 | 148 | 2007 |
Cystic Fibrosis-Niche Adaptation of Pseudomonas aeruginosa Reduces Virulence in Multiple Infection Hosts NI Lorè, C Cigana, I De Fino, C Riva, M Juhas, S Schwager, L Eberl, ... PloS one 7 (4), e35648, 2012 | 142 | 2012 |
Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease C Rigauts, J Aizawa, SL Taylor, GB Rogers, M Govaerts, P Cos, L Ostyn, ... European Respiratory Journal 59 (5), 2022 | 115 | 2022 |
Host-pathogen interplay in the respiratory environment of cystic fibrosis LM Yonker, C Cigana, BP Hurley, A Bragonzi Journal of cystic fibrosis 14 (4), 431-439, 2015 | 91 | 2015 |
Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections C Cigana, NI Lorè, C Riva, I De Fino, L Spagnuolo, B Sipione, G Rossi, ... Scientific reports 6 (1), 21465, 2016 | 87 | 2016 |
Positive Signature-Tagged Mutagenesis in Pseudomonas aeruginosa: Tracking Patho-Adaptive Mutations Promoting Airways Chronic Infection I Bianconi, A Milani, C Cigana, M Paroni, RC Levesque, G Bertoni, ... PLoS pathogens 7 (2), e1001270, 2011 | 75 | 2011 |
BIIL 284 reduces neutrophil numbers but increases P. aeruginosa bacteremia and inflammation in mouse lungs G Döring, A Bragonzi, M Paroni, FF Aktürk, C Cigana, A Schmidt, D Gilpin, ... Journal of Cystic Fibrosis 13 (2), 156-163, 2014 | 71 | 2014 |
Activation of Human Toll-like receptor 4 (TLR4)· myeloid differentiation factor 2 (MD-2) by hypoacylated lipopolysaccharide from a clinical isolate of Burkholderia cenocepacia F Di Lorenzo, Ł Kubik, A Oblak, NI Lore, C Cigana, R Lanzetta, M Parrilli, ... Journal of Biological Chemistry 290 (35), 21305-21319, 2015 | 65 | 2015 |
Integrated whole‐genome screening for Pseudomonas aeruginosa virulence genes using multiple disease models reveals that pathogenicity is host specific JF Dubern, C Cigana, M De Simone, J Lazenby, M Juhas, S Schwager, ... Environmental microbiology 17 (11), 4379-4393, 2015 | 61 | 2015 |
Dampening Host Sensing and Avoiding Recognition in Pseudomonas aeruginosa Pneumonia C Cigana, NI Lore, ML Bernardini, A Bragonzi BioMed Research International 2011 (1), 852513, 2011 | 59 | 2011 |
Efficacy of the novel antibiotic POL7001 in preclinical models of Pseudomonas aeruginosa pneumonia C Cigana, F Bernardini, M Facchini, B Alcalá-Franco, C Riva, I De Fino, ... Antimicrobial agents and chemotherapy 60 (8), 4991-5000, 2016 | 56 | 2016 |
IL-17A impairs host tolerance during airway chronic infection by Pseudomonas aeruginosa NI Lorè, C Cigana, C Riva, I De Fino, A Nonis, L Spagnuolo, B Sipione, ... Scientific reports 6 (1), 25937, 2016 | 56 | 2016 |
Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis A Rimessi, C Pozzato, L Carparelli, A Rossi, S Ranucci, I De Fino, ... Science advances 6 (19), eaax9093, 2020 | 52 | 2020 |
Staphylococcus aureus Impacts Pseudomonas aeruginosa Chronic Respiratory Disease in Murine Models C Cigana, I Bianconi, R Baldan, M De Simone, C Riva, B Sipione, G Rossi, ... The Journal of infectious diseases 217 (6), 933-942, 2018 | 47 | 2018 |
Assessing Pseudomonas aeruginosa Virulence and the Host Response Using Murine Models of Acute and Chronic Lung Infection I Kukavica-Ibrulj, M Facchini, C Cigana, RC Levesque, A Bragonzi Pseudomonas Methods and Protocols, 757-771, 2014 | 42 | 2014 |
The IL-17A/IL-17RA axis in pulmonary defence and immunopathology NI Lorè, A Bragonzi, C Cigana Cytokine & growth factor reviews 30, 19-27, 2016 | 41 | 2016 |
Host genetic background influences the response to the opportunistic Pseudomonas aeruginosa infection altering cell-mediated immunity and bacterial replication M De Simone, L Spagnuolo, NI Lorè, G Rossi, C Cigana, I De Fino, ... PloS one 9 (9), e106873, 2014 | 39 | 2014 |