| Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics P Song, LR Wu, YH Yan, JX Zhang, T Chu, LN Kwong, AA Patel, ... Nature biomedical engineering 6 (3), 232-245, 2022 | 187 | 2022 |
| Molecular hybridization probes for complex sequence capture and analysis D Zhang, J Wang, Y Yan WO Patent US20200080136A1, 2020 | 71 | 2020 |
| Selective multiplexed enrichment for the detection and quantitation of low-fraction DNA variants via low-depth sequencing P Song, SX Chen, YH Yan, A Pinto, LY Cheng, P Dai, AA Patel, DY Zhang Nature biomedical engineering 5 (7), 690-701, 2021 | 42 | 2021 |
| Modular probes for enriching and detecting complex nucleic acid sequences JS Wang*, YH Yan*, DY Zhang Nature chemistry 9 (12), 1222, 2017 | 40 | 2017 |
| Low-level parental somatic mosaic SNVs in exomes from a large cohort of trios with diverse suspected Mendelian conditions T Gambin, Q Liu, JA Karolak, CM Grochowski, NG Xie, LR Wu, YH Yan, ... Genetics in Medicine 22 (11), 1768-1776, 2020 | 38 | 2020 |
| Confirming putative variants at≤ 5% allele frequency using allele enrichment and Sanger sequencing YH Yan, SX Chen, LY Cheng, AY Rodriguez, R Tang, K Cabrera, ... Scientific reports 11 (1), 11640, 2021 | 31 | 2021 |
| RNA Scaffold: Designed to Co-localize Enzymes. ZTGEM 2012), M Chen Methods in molecular biology (Clifton, NJ) 1316, 105-112, 2014 | 4* | 2014 |
| Detecting and quantitating low fraction DNA variants with low-depth sequencing P Song, SX Chen, YH Yan, A Pinto, LY Cheng, P Dai, AA Patel, DY Zhang bioRxiv, 2020.04. 26.061747, 2020 | 3 | 2020 |
| Microsatellite Instability Detection in Clinical Cancer Samples: A Multiplex qPCR Approach without Matching Normal Samples W Chen*, YH Yan*, B Young, A Pinto, Q Jiang, N Song, W Yao, DY Zhang, ... medRxiv, 2023 | 1 | 2023 |
| 925P Analytical performance of a next-generation sequencing (NGS) assay kit for assessing homologous recombination deficiency (HRD) from solid tumor samples L Liu, K Roessler, S Bilke, Y Ding, D Erlandson, Y Fu, B Hariharan, S Katz, ... Annals of Oncology 33, S969, 2022 | 1 | 2022 |
| Encoding multiple digital DNA signals in a single analog channel YH Yan, DY Zhang, LR Wu Nucleic Acids Research 48 (11), e65-e65, 2020 | 1 | 2020 |
| Microsatellite Instability Detection in Cancer: A Multiplex qPCR Approach that Obviates the Need for Matching Normal Samples W Chen*, YH Yan*, B Young, A Pinto, Q Jiang, N Song, A Yaseen, W Yao, ... Clinical Chemistry, hvae045, 2024 | | 2024 |
| High sensitivity detection of microsatellite loci by blocker displacement amplification with multiple blockers and its use in microsatellite instability detection Y Yan US Patent US20220298564A1, 2022 | | 2022 |
| High sensitivity qPCR microsatellite instability detection in FFPE tissue YH Yan, B Young, Z Wang, A Yaseen, A Pinto, D Zhang Cancer Research 82 (12_Supplement), 2806-2806, 2022 | | 2022 |
| Symbolic Sequencing of DNA and RNA via sequence encoding DY Zhang, Y Yan WO Patent WO2019046768A1, 2019 | | 2019 |
| Rationally Designed Hybridization Systems for Nucleic Acid Diagnostics and Sequence Analysis YH Yan Rice University, 2019 | | 2019 |
