Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts TK Karikari, TA Pascoal, NJ Ashton, S Janelidze, AL Benedet, ... The Lancet Neurology 19 (5), 422-433, 2020 | 1074 | 2020 |
Plasma p-tau231: a new biomarker for incipient Alzheimer’s disease pathology NJ Ashton, TA Pascoal, TK Karikari, AL Benedet, J Lantero-Rodriguez, ... Acta neuropathologica 141, 709-724, 2021 | 508 | 2021 |
Microglial activation and tau propagate jointly across Braak stages TA Pascoal, AL Benedet, NJ Ashton, MS Kang, J Therriault, M Chamoun, ... Nature medicine 27 (9), 1592-1599, 2021 | 397 | 2021 |
A multicentre validation study of the diagnostic value of plasma neurofilament light NJ Ashton, S Janelidze, A Al Khleifat, A Leuzy, EL van der Ende, ... Nature communications 12 (1), 3400, 2021 | 379 | 2021 |
Differences between plasma and cerebrospinal fluid glial fibrillary acidic protein levels across the Alzheimer disease continuum AL Benedet, M Milà-Alomà, A Vrillon, NJ Ashton, TA Pascoal, F Lussier, ... JAMA neurology 78 (12), 1471-1483, 2021 | 357 | 2021 |
Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain KP Ng, TA Pascoal, S Mathotaarachchi, J Therriault, MS Kang, M Shin, ... Alzheimer's research & therapy 9, 1-9, 2017 | 353 | 2017 |
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer’s Disease Neuroimaging Initiative TK Karikari, AL Benedet, NJ Ashton, J Lantero Rodriguez, A Snellman, ... Molecular psychiatry 26 (2), 429-442, 2021 | 297 | 2021 |
Association of apolipoprotein E ε4 with medial temporal tau independent of amyloid-β J Therriault, AL Benedet, TA Pascoal, S Mathotaarachchi, M Chamoun, ... JAMA neurology 77 (4), 470-479, 2020 | 220 | 2020 |
Diagnostic accuracy of a plasma phosphorylated tau 217 immunoassay for Alzheimer disease pathology NJ Ashton, WS Brum, G Di Molfetta, AL Benedet, B Arslan, E Jonaitis, ... JAMA neurology 81 (3), 255-263, 2024 | 214 | 2024 |
18F-MK-6240 PET for early and late detection of neurofibrillary tangles TA Pascoal, J Therriault, AL Benedet, M Savard, FZ Lussier, M Chamoun, ... Brain 143 (9), 2818-2830, 2020 | 210 | 2020 |
Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical utility TK Karikari, NJ Ashton, G Brinkmalm, WS Brum, AL Benedet, ... Nature Reviews Neurology 18 (7), 400-418, 2022 | 209 | 2022 |
Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer’s disease NM Lyra e Silva, RA Gonçalves, TA Pascoal, RAS Lima-Filho, ... Translational psychiatry 11 (1), 251, 2021 | 208 | 2021 |
Biomarker modeling of Alzheimer’s disease using PET-based Braak staging J Therriault, TA Pascoal, FZ Lussier, C Tissot, M Chamoun, G Bezgin, ... Nature aging 2 (6), 526-535, 2022 | 185 | 2022 |
In vivo quantification of neurofibrillary tangles with [18F]MK-6240 TA Pascoal, M Shin, MS Kang, M Chamoun, D Chartrand, ... Alzheimer's research & therapy 10, 1-14, 2018 | 168 | 2018 |
Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease B Bellaver, G Povala, PCL Ferreira, JP Ferrari-Souza, DT Leffa, ... Nature medicine 29 (7), 1775-1781, 2023 | 167 | 2023 |
Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer’s disease TA Pascoal, S Mathotaarachchi, S Mohades, AL Benedet, CO Chung, ... Molecular psychiatry 22 (2), 306-311, 2017 | 147 | 2017 |
Mild behavioral impairment is associated with β‐amyloid but not tau or neurodegeneration in cognitively intact elderly individuals FZ Lussier, TA Pascoal, M Chamoun, J Therriault, C Tissot, M Savard, ... Alzheimer's & dementia 16 (1), 192-199, 2020 | 146 | 2020 |
Association of phosphorylated tau biomarkers with amyloid positron emission tomography vs tau positron emission tomography J Therriault, M Vermeiren, S Servaes, C Tissot, NJ Ashton, AL Benedet, ... JAMA neurology 80 (2), 188-199, 2023 | 141 | 2023 |
Identifying incipient dementia individuals using machine learning and amyloid imaging S Mathotaarachchi, TA Pascoal, M Shin, AL Benedet, MS Kang, ... Neurobiology of aging 59, 80-90, 2017 | 125 | 2017 |
Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease NJ Ashton, AL Benedet, TA Pascoal, TK Karikari, J Lantero-Rodriguez, ... EBioMedicine 76, 2022 | 123 | 2022 |