Proteins containing expanded polyglutamine tracts and neurodegenerative disease A Adegbuyiro, F Sedighi, AW Pilkington IV, S Groover, J Legleiter Biochemistry 56 (9), 1199-1217, 2017 | 161 | 2017 |
Lipid membranes influence the ability of small molecules to inhibit huntingtin fibrillization M Beasley, AR Stonebraker, I Hasan, KL Kapp, BJ Liang, G Agarwal, ... Biochemistry 58 (43), 4361-4373, 2019 | 30 | 2019 |
SUMOylation prevents huntingtin fibrillization and localization onto lipid membranes F Sedighi, A Adegbuyiro, J Legleiter ACS Chemical Neuroscience 11 (3), 328-343, 2019 | 28 | 2019 |
Mitochondrial membranes modify mutant huntingtin aggregation A Adegbuyiro, F Sedighi, P Jain, MV Pinti, C Siriwardhana, JM Hollander, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1863 (10), 183663, 2021 | 16 | 2021 |
Oxidation promotes distinct huntingtin aggregates in the presence and absence of membranes A Adegbuyiro, AR Stonebraker, F Sedighi, CK Fan, B Hodges, P Li, ... Biochemistry 61 (14), 1517-1530, 2022 | 6 | 2022 |
Oligomerization enhances huntingtin membrane activity but is suppressed by covalent crosslinking F Sedighi, A Skeens, A Adegbuyiro, J Bard, C Siriwardhana, E Donley, ... bioRxiv, 2023.03. 01.530665, 2023 | 5 | 2023 |
Blocking the ability of huntingtin to bind membranes: a therapeutic strategy for Huntington’s disease C Siriwardhana, A Adegbuyiro, F Sedighi, AR Stonebraker, S Leonard, ... bioRxiv, 2024.07. 17.603089, 2024 | | 2024 |
Oxidation of Huntingtin Modulates its Aggregation and Interaction with Membranes A Adegbuyiro, F Sedighi, J Legleiter The FASEB Journal 35, 2021 | | 2021 |
Aggregation State of Huntingtin Regulates Its Interaction with Lipid Membranes F Sedighi, A Adegbuyiro, JA Legleiter Biophysical Journal 118 (3), 540a, 2020 | | 2020 |
Cardiolipin Modulates Huntingtin Aggregation and Binding to Mitochondrial Membranes A Adegbuyiro, F Sedighi, J Legleiter Biophysical Journal 118 (3), 216a, 2020 | | 2020 |
Targeting the Nt17 of the huntingtin protein via natural and chemical modifications: impact on aggregation and membrane interactions F Sedighi West Virginia University, 2020 | | 2020 |
SUMOylation of the Nt17 domain of huntingtin influences aggregation and binding to lipid membranes F Sedighi, JA Legleiter Biophysical Journal 116 (3), 492a-493a, 2019 | | 2019 |
Ab Initio investigation of Fluorinated Oxyluciferin F Sedighi, H Sabzyan | | 2013 |
COMPUTATIONAL STUDY OF THE EFFECT OF FLUORINE SUBSTITUTION ON THE STRUCTURAL AND SPECTROSCOPIC CHARACTERISTICS OF LUCEFRIN AND ITS ROLE IN BIOLUMINESCENCE F SEDIGHI, H SABZIYAN | | 2013 |