Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency E Giampazolias, B Zunino, S Dhayade, F Bock, C Cloix, K Cao, A Roca, ... Nature cell biology 19 (9), 1116-1129, 2017 | 241 | 2017 |
Fam49/CYRI interacts with Rac1 and locally suppresses protrusions L Fort, JM Batista, PA Thomason, HJ Spence, JA Whitelaw, L Tweedy, ... Nature cell biology 20 (10), 1159-1171, 2018 | 80 | 2018 |
NFκB is a central regulator of protein quality control in response to protein aggregation stresses via autophagy modulation M Nivon, L Fort, P Muller, E Richet, S Simon, B Guey, M Fournier, ... Molecular biology of the cell 27 (11), 1712-1727, 2016 | 51 | 2016 |
N-WASP control of LPAR1 trafficking establishes response to self-generated LPA gradients to promote pancreatic cancer cell metastasis A Juin, HJ Spence, KJ Martin, E McGhee, M Neilson, MFA Cutiongco, ... Developmental cell 51 (4), 431-445. e7, 2019 | 46 | 2019 |
Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility X Zhang, G Lavoie, L Fort, EL Huttlin, J Tcherkezian, JA Galan, H Gu, ... Molecular and cellular biology, 2013 | 45 | 2013 |
CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation AH Le, T Yelland, NR Paul, L Fort, S Nikolaou, S Ismail, LM Machesky Journal of Cell Biology 220 (9), e202012114, 2021 | 30 | 2021 |
Loss of N‐WASP drives early progression in an Apc model of intestinal tumourigenesis HT Morris, L Fort, HJ Spence, R Patel, DF Vincent, JH Park, SB Snapper, ... The Journal of Pathology 245 (3), 337-348, 2018 | 21 | 2018 |
Stem cell conversion to the cardiac lineage requires nucleotide signalling from apoptosing cells L Fort, V Gama, IG Macara Nature cell biology 24 (4), 434-447, 2022 | 17 | 2022 |
CYRI/Fam49 proteins represent a new class of Rac1 interactors JA Whitelaw, S Lilla, NR Paul, L Fort, S Zanivan, LM Machesky Communicative & Integrative Biology 12 (1), 112-118, 2019 | 11 | 2019 |
Apoptotic Find-me Signals are an Essential Driver of Stem Cell Conversion To The Cardiac Lineage L Fort, V Gama, IG Macara bioRxiv, 2021.06. 21.449262, 2021 | 3 | 2021 |
Chemotaxis in Pacreatic Ductal Adenocarcinoma Metastasis: An Unexpected Role of NWASP in Maintaining Self-Generated Gradients and LPA Receptor Recycling A Juin, HJ Spence, KJ Martin, E McGhee, M Neilson, MFA Cutiongco, ... | 2 | 2018 |
Actomyosin Contractility is a Potent Suppressor of Mesoderm Induction by Human Pluripotent Stem Cells L Fort, W Wang, I Macara bioRxiv, 2024.09. 30.615859, 2024 | | 2024 |
CYRI-B mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake S Nikolaou, A Juin, JA Whitelaw, NR Paul, L Fort, C Nixon, HJ Spence, ... Elife 13, e83712, 2024 | | 2024 |
CYRI-B loss promotes enlarged mature focal adhesions and restricts microtubule and ERC1 access to the cell leading edge JA Whitelaw, S Lilla, S Nikolaou, L Tweedy, L Fort, NR Paul, S Zanivan, ... bioRxiv, 2024.03. 26.586838, 2024 | | 2024 |
Pathway to Independence: the future of developmental biology P Agarwal, C Cadart, L Fort, J Gahan, L Greenspan, T Juan, P Kameneva, ... Development 150 (19), 2023 | | 2023 |
Messenger functions of cell death during development and homeostasis L Fort Biochemical Society Transactions 51 (2), 759-769, 2023 | | 2023 |
Effect of N-Wasp knockout on tumour burden and survival in murine models of intestinal tumorigenesis and its potential as a prognostic biomarker in human colorectal cancer HT Morris, L Fort, RA Ridgway, OJ Sansom, FA Carey, LM Machesky The Lancet 389, S71, 2017 | | 2017 |
CYRIPS (Fam49) proteins are local inhibitors of Rac1 and Scar/WAVE induced lamellipodia. L Fort, J Batista, P Thomason, H Spence, J Greaves, K Martin, K Anderson, ... Molecular Biology Of The Cell 28, 2017 | | 2017 |
FAM49B: first negative regulator of the Scar/WAVE complex. From evolution to an in vivo analysis L Fort University of Glasgow, 2017 | | 2017 |
A Highlights from MBoC Selection: NFκB is a central regulator of protein quality control in response to protein aggregation stresses via autophagy modulation M Nivon, L Fort, P Muller, E Richet, S Simon, B Guey, M Fournier, ... Molecular Biology of the Cell 27 (11), 1712, 2016 | | 2016 |