Epithelial-mesenchymal transitions in development and disease JP Thiery, H Acloque, RYJ Huang, MA Nieto cell 139 (5), 871-890, 2009 | 11631 | 2009 |
EMT: 2016 MA Nieto, RYJ Huang, RA Jackson, JP Thiery cell 166 (1), 21-45, 2016 | 4577 | 2016 |
Guidelines and definitions for research on epithelial–mesenchymal transition J Yang, P Antin, G Berx, C Blanpain, T Brabletz, M Bronner, K Campbell, ... Nature reviews Molecular cell biology 21 (6), 341-352, 2020 | 1725 | 2020 |
Epithelial‐mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients TZ Tan, QH Miow, Y Miki, T Noda, S Mori, RYJ Huang, JP Thiery EMBO molecular medicine 6 (10), 1279-1293, 2014 | 717 | 2014 |
Dual role of autophagy in hallmarks of cancer SS Singh, S Vats, AYQ Chia, TZ Tan, S Deng, MS Ong, F Arfuso, CT Yap, ... Oncogene 37 (9), 1142-1158, 2018 | 535 | 2018 |
Early events in cell adhesion and polarity during epithelial-mesenchymal transition RYJ Huang, P Guilford, JP Thiery Journal of cell science 125 (19), 4417-4422, 2012 | 495 | 2012 |
An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor … RYJ Huang, MK Wong, TZ Tan, KT Kuay, AHC Ng, VY Chung, YS Chu, ... Cell death & disease 4 (11), e915-e915, 2013 | 460 | 2013 |
Molecular subtypes of urothelial bladder cancer: results from a meta-cohort analysis of 2411 tumors TZ Tan, M Rouanne, KT Tan, RYJ Huang, JP Thiery European urology 75 (3), 423-432, 2019 | 279 | 2019 |
Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma HL Penny, JL Sieow, G Adriani, WH Yeap, P See Chi Ee, B San Luis, ... Oncoimmunology 5 (8), e1191731, 2016 | 250 | 2016 |
Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer TZ Tan, QH Miow, RYJ Huang, MK Wong, J Ye, JA Lau, MC Wu, ... EMBO molecular medicine 5 (7), 1051-1066, 2013 | 236 | 2013 |
Lgr5 marks stem/progenitor cells in ovary and tubal epithelia A Ng, S Tan, G Singh, P Rizk, Y Swathi, TZ Tan, RYJ Huang, ... Nature cell biology 16 (8), 745-757, 2014 | 235 | 2014 |
Screening therapeutic EMT blocking agents in a three-dimensional microenvironment AR Aref, RYJ Huang, W Yu, KN Chua, W Sun, TY Tu, J Bai, WJ Sim, ... Integrative Biology 5 (2), 381-389, 2013 | 210 | 2013 |
AXL-driven EMT state as a targetable conduit in cancer J Antony, RYJ Huang Cancer research 77 (14), 3725-3732, 2017 | 180 | 2017 |
Thymoquinone inhibits bone metastasis of breast cancer cells through abrogation of the CXCR4 signaling axis MK Shanmugam, KS Ahn, A Hsu, CC Woo, Y Yuan, KHB Tan, ... Frontiers in pharmacology 9, 1294, 2018 | 176 | 2018 |
GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification VY Chung, TZ Tan, M Tan, MK Wong, KT Kuay, Z Yang, J Ye, J Muller, ... Scientific reports 6 (1), 19943, 2016 | 173 | 2016 |
FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway M Asad, MK Wong, TZ Tan, M Choolani, J Low, S Mori, D Virshup, ... Cell death & disease 5 (7), e1346-e1346, 2014 | 148 | 2014 |
Pure-type clear cell carcinoma of the ovary as a distinct histological type and improved survival in patients treated with paclitaxel-platinum-based chemotherapy in pure-type … CM Ho, YJ Huang, TC Chen, SH Huang, FS Liu, CCC Chien, MH Yu, ... Gynecologic oncology 94 (1), 197-203, 2004 | 123 | 2004 |
The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype–specific therapeutic target for ovarian cancer J Antony, TZ Tan, Z Kelly, J Low, M Choolani, C Recchi, H Gabra, ... Science signaling 9 (448), ra97-ra97, 2016 | 118 | 2016 |
A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets D Jia, Z Liu, N Deng, TZ Tan, RYJ Huang, B Taylor-Harding, DJ Cheon, ... Cancer letters 382 (2), 203-214, 2016 | 117 | 2016 |
Up-regulation of interleukin-6 in human ovarian cancer cell via a Gi/PI3K–Akt/NF-κB pathway by lysophosphatidic acid, an ovarian cancer-activating factor CH Chou, LH Wei, ML Kuo, YJ Huang, KP Lai, CA Chen, CY Hsieh Carcinogenesis 26 (1), 45-52, 2005 | 117 | 2005 |